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Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…

Computation and Language · Computer Science 2026-04-28 Yimin Deng , Zhenxi Lin , Yejing Wang , Guoshuai Zhao , Pengyue Jia , Zichuan Fu , Derong Xu , Yefeng Zheng , Xiangyu Zhao , Li Zhu , Xian Wu , Xueming Qian

Effectiveness and interpretability are two essential properties for trustworthy AI systems. Most recent studies in visual reasoning are dedicated to improving the accuracy of predicted answers, and less attention is paid to explaining the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Shi Chen , Qi Zhao

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang

English-centric large language models (LLMs) often show strong multilingual capabilities. However, their multilingual performance remains unclear and is under-evaluated for many other languages. Most benchmarks for multilinguality focus on…

Computation and Language · Computer Science 2025-06-03 Amir Hossein Kargaran , Ali Modarressi , Nafiseh Nikeghbal , Jana Diesner , François Yvon , Hinrich Schütze

The ability to organically reason over and with both text and images is a pillar of human intelligence, yet the ability of Multimodal Large Language Models (MLLMs) to perform such multimodal reasoning remains under-explored. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Yunzhuo Hao , Jiawei Gu , Huichen Will Wang , Linjie Li , Zhengyuan Yang , Lijuan Wang , Yu Cheng

Multimodal recommender systems leverage diverse data sources, such as user interactions, content features, and contextual information, to address challenges like cold-start and data sparsity. However, existing methods often suffer from one…

Information Retrieval · Computer Science 2026-02-24 Adamya Shyam , Venkateswara Rao Kagita , Bharti Rana , Vikas Kumar

The reasoning capabilities of LLM (Large Language Model) are widely acknowledged in recent research, inspiring studies on tool learning and autonomous agents. LLM serves as the "brain" of the agent, orchestrating multiple tools for…

Machine Learning · Computer Science 2024-03-26 Xiangyan Liu , Rongxue Li , Wei Ji , Tao Lin

Despite impressive advancements in recent multimodal reasoning approaches, they are still limited in flexibility and efficiency, as these models typically process only a few fixed modality inputs and require updates to numerous parameters.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Shoubin Yu , Jaehong Yoon , Mohit Bansal

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

Artificial Intelligence · Computer Science 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

Multimodal clinical prediction faces three challenges: multiple foundation models (FMs) with complementary strengths per modality, pervasive missing modalities at training and test time, and sample-specific variation in modality…

Machine Learning · Computer Science 2026-05-19 Seungik Cho , Anqi Li , Wei Qiu

Explainable deep learning models are advantageous in many situations. Prior work mostly provide unimodal explanations through post-hoc approaches not part of the original system design. Explanation mechanisms also ignore useful textual…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Varun Nagaraj Rao , Xingjian Zhen , Karen Hovsepian , Mingwei Shen

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Understanding the contents of multimodal documents is essential to accurately extract relevant evidence and use it for reasoning. Existing document understanding models tend to generate answers with a single word or phrase directly,…

Information Retrieval · Computer Science 2024-08-15 Jinxu Zhang

Temporal knowledge graph reasoning aims to predict future events with knowledge of existing facts and plays a key role in various downstream tasks. Previous methods focused on either graph structure learning or semantic reasoning, failing…

Computation and Language · Computer Science 2025-06-18 Yimin Deng , Yuxia Wu , Yejing Wang , Guoshuai Zhao , Li Zhu , Qidong Liu , Derong Xu , Zichuan Fu , Xian Wu , Yefeng Zheng , Xiangyu Zhao , Xueming Qian

We present MedXIAOHE, a medical vision-language foundation model designed to advance general-purpose medical understanding and reasoning in real-world clinical applications. MedXIAOHE achieves state-of-the-art performance across diverse…

Effective clinical decision-making depends on iterative, multimodal reasoning across diverse sources of evidence. The recent emergence of multimodal reasoning models has significantly transformed the landscape of solving complex tasks.…

Computation and Language · Computer Science 2025-11-04 Zhongzhen Huang , Linjie Mu , Yakun Zhu , Xiangyu Zhao , Shaoting Zhang , Xiaofan Zhang

Deep models that are both effective and explainable are desirable in many settings; prior explainable models have been unimodal, offering either image-based visualization of attention weights or text-based generation of post-hoc…

Artificial Intelligence · Computer Science 2018-02-23 Dong Huk Park , Lisa Anne Hendricks , Zeynep Akata , Anna Rohrbach , Bernt Schiele , Trevor Darrell , Marcus Rohrbach
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