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Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

The field of hypothesis generation promises to reduce costs in neuroscience by narrowing the range of interventional studies needed to study various phenomena. Existing machine learning methods can generate scientific hypotheses from…

Machine Learning · Computer Science 2025-07-04 Zachary C. Brown , David Carlson

Learning causal relationships between variables from data is a fundamental research area with many applications across disciplines. Most existing causal discovery algorithms rely on the assumptions that (i) the underlying system is acyclic,…

Machine Learning · Computer Science 2026-05-19 Alpar Turkoglu , Muralikrishnna G. Sethuraman , Faramarz Fekri

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these…

Machine Learning · Computer Science 2026-05-21 Jianhong Chen , Naichen Shi , Xubo Yue

Causal discovery is a difficult problem that typically relies on strong assumptions on the data-generating model, such as non-Gaussianity. In practice, many modern applications provide multiple related views of the same system, which has…

Machine Learning · Computer Science 2025-09-29 Ambroise Heurtebise , Omar Chehab , Pierre Ablin , Alexandre Gramfort , Aapo Hyvärinen

The widespread availability of complex time series data in various domains such as environmental science, epidemiology, and economics demands robust causal discovery methods that can identify intricate contemporaneous and lagged…

Machine Learning · Computer Science 2026-05-12 Omar Faruque , Sahara Ali , Xue Zheng , Jianwu Wang

Causal learning is a fundamental problem in statistics and science, offering insights into predicting the effects of unseen treatments on a system. Despite recent advances in this topic, most existing causal discovery algorithms operate…

Machine Learning · Statistics 2024-02-27 Muralikrishnna G. Sethuraman , Faramarz Fekri

Discovering causal relations from observational data becomes possible with additional assumptions such as considering the functional relations to be constrained as nonlinear with additive noise (ANM). Even with strong assumptions, causal…

Machine Learning · Computer Science 2023-06-27 Pedro Sanchez , Xiao Liu , Alison Q O'Neil , Sotirios A. Tsaftaris

Real world systems evolve in continuous-time according to their underlying causal relationships, yet their dynamics are often unknown. Existing approaches to learning such dynamics typically either discretize time -- leading to poor…

Machine Learning · Computer Science 2025-12-17 Nicholas Tagliapietra , Katharina Ensinger , Christoph Zimmer , Osman Mian

Streamflow forecasting is crucial for water resource management and risk mitigation. While deep learning models have achieved strong predictive performance, they often overlook underlying physical processes, limiting interpretability and…

Machine Learning · Computer Science 2025-12-19 Shu Wan , Reepal Shah , John Sabo , Huan Liu , K. Selçuk Candan

This paper studies causal discovery in irregularly sampled time series-a key challenge in risk-sensitive domains like finance, healthcare, and climate science, where missing data and inconsistent sampling frequencies distort causal…

Machine Learning · Computer Science 2026-05-12 Weihong Li , Baohong Li , Anpeng Wu , Zhihan Li , Ming Ma , Keting Yin , Kun Kuang

In this study, we address causal inference when only observational data and a valid causal ordering from the causal graph are available. We introduce a set of flow models that can recover component-wise, invertible transformation of…

Machine Learning · Computer Science 2024-12-16 Minh Khoa Le , Kien Do , Truyen Tran

Heterogeneity in medical data, e.g., from data collected at different sites and with different protocols in a clinical study, is a fundamental hurdle for accurate prediction using machine learning models, as such models often fail to…

Machine Learning · Computer Science 2021-07-13 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

We develop a novel identification strategy as well as a new estimator for context-dependent causal inference in non-parametric triangular models with non-separable disturbances. Departing from the common practice, our analysis does not rely…

Econometrics · Economics 2024-04-09 Nir Billfeld , Moshe Kim

Causal inference in spatio-temporal settings is critically hindered by unmeasured confounders with complex spatio-temporal dynamics and the prevalence of multi-resolution data. While diffusion models present a promising avenue for…

Machine Learning · Statistics 2026-04-07 Xinwen Liu , Lei Qian , Song Xi Chen , Niansheng Tang

In causal discovery, non-Gaussianity has been used to characterize the complete configuration of a Linear Non-Gaussian Acyclic Model (LiNGAM), encompassing both the causal ordering of variables and their respective connection strengths.…

Machine Learning · Computer Science 2025-08-08 Tian-Le Yang , Kuang-Yao Lee , Kun Zhang , Joe Suzuki

Predicting causal structure from time series data is crucial for understanding complex phenomena in physiology, brain connectivity, climate dynamics, and socio-economic behaviour. Causal discovery in time series is hindered by the…

Machine Learning · Computer Science 2026-01-06 Pedro P. Sanchez , Damian Machlanski , Steven McDonagh , Sotirios A. Tsaftaris

Causal discovery aims to uncover causal structure among a set of variables. Score-based approaches mainly focus on searching for the best Directed Acyclic Graph (DAG) based on a predefined score function. However, most of them are not…

Machine Learning · Computer Science 2023-03-13 Wenqian Li , Yinchuan Li , Shengyu Zhu , Yunfeng Shao , Jianye Hao , Yan Pang

It is commonplace to encounter heterogeneous or nonstationary data, of which the underlying generating process changes across domains or over time. Such a distribution shift feature presents both challenges and opportunities for causal…

Machine Learning · Computer Science 2020-06-26 Biwei Huang , Kun Zhang , Jiji Zhang , Joseph Ramsey , Ruben Sanchez-Romero , Clark Glymour , Bernhard Schölkopf

Structural causal models (SCMs) are widely used in various disciplines to represent causal relationships among variables in complex systems. Unfortunately, the underlying causal structure is often unknown, and estimating it from data…

Machine Learning · Computer Science 2024-01-17 Tianyu Chen , Kevin Bello , Bryon Aragam , Pradeep Ravikumar