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As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Automated lesion segmentation in PET/CT scans is crucial for improving clinical workflows and advancing cancer diagnostics. However, the task is challenging due to physiological variability, different tracers used in PET imaging, and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Maximilian Rokuss , Balint Kovacs , Yannick Kirchhoff , Shuhan Xiao , Constantin Ulrich , Klaus H. Maier-Hein , Fabian Isensee

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Diffusion probabilistic model (DPM) recently becomes one of the hottest topic in computer vision. Its image generation application such as Imagen, Latent Diffusion Models and Stable Diffusion have shown impressive generation capabilities,…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Junde Wu , Rao Fu , Huihui Fang , Yu Zhang , Yehui Yang , Haoyi Xiong , Huiying Liu , Yanwu Xu

Transforming the resistive plate chambers from charged-particle into gamma-quanta detectors opens the way towards their application as a basic element of a hybrid imaging system, which combines positron emission tomography (PET) with…

Instrumentation and Detectors · Physics 2015-06-12 Georgi Georgiev , Nevena Ilieva , Venelin Kozhuharov , Iglika Lessigiarska , Leandar Litov , Borislav Pavlov , Peicho Petkov

Deep learning has proven to be important for CT image denoising. However, such models are usually trained under supervision, requiring paired data that may be difficult to obtain in practice. Diffusion models offer unsupervised means of…

Proton therapy's full potential is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatment planning. Spatiotemporal Emission Reconstruction from…

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

Small animal Positron Emission Tomography (PET) is dedicated to small animal imaging. Animals used in experiments, such as rats and monkeys, are often much smaller than human bodies, which requires higher position and energy precision of…

Signal Processing · Electrical Eng. & Systems 2018-06-26 Jiaming Lu , Lei Zhao , Peipei Deng , Bowen Li , Kairen Chen , Shubin Liu , Qi An

Building large-scale foundation model for PET imaging is hindered by limited access to labeled data and insufficient computational resources. To overcome data scarcity and efficiency limitations, we propose ALL-PET, a low-resource, low-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Bin Huang , Kang Chen , Bingxuan Li , Huafeng Liu , Qiegen Liu

Direct reconstruction methods have been developed to estimate parametric images directly from the measured PET sinograms by combining the PET imaging model and tracer kinetics in an integrated framework. Due to limited counts received,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Kuang Gong , Ciprian Catana , Jinyi Qi , Quanzheng Li

Potential radioactive hazards in full-dose positron emission tomography (PET) imaging remain a concern, whereas the quality of low-dose images is never desirable for clinical use. So it is of great interest to translate low-dose PET images…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Yang Zhou , Zhiwen Yang , Hui Zhang , Eric I-Chao Chang , Yubo Fan , Yan Xu

The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

Purpose: Neural network image reconstruction directly from measurement data is a relatively new field of research, that until now has been limited to producing small single-slice images (e.g., 1x128x128). This paper proposes a novel and…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 William Whiteley , Wing K. Luk , Jens Gregor

This paper presents a novel image reconstruction pipeline for three-gamma (3-{\gamma}) positron emission tomography (PET) aimed at improving spatial resolution and reducing noise in nuclear medicine; the proposed Direct3{\gamma} pipeline…

Medical Physics · Physics 2025-06-23 Youness Mellak , Alexandre Bousse , Thibaut Merlin , Debora Giovagnoli , Dimitris Visvikis

Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub

Low-count reconstruction remains a challenge for Positron Emission Tomography (PET) even with the recent progress in time-of-flight (TOF) resolution. In this context, the bias between the acquired histogram, consisting of low values or…

Medical Physics · Physics 2023-01-12 Maxime Toussaint , Francis Loignon-Houle , Roger Lecomte , Jean-Pierre Dussault

Accurate characterization of ferroelectric properties in polymer piezoelectrics is critical for optimizing the performance of flexible and wearable ultrasound transducers, such as screen-printed PVDF devices. Standard charge measurement…

Systems and Control · Electrical Eng. & Systems 2024-10-23 Marc-Andre Wessner , Federico Villani , Sofia Papa , Kirill Keller , Laura Ferrari , Francesco Greco , Luca Benini , Christoph Leitner
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