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A pretrain-finetune strategy is widely used to reduce the overfitting that can occur when data is insufficient for CNN training. First few layers of a CNN pretrained on a large-scale RGB dataset are capable of acquiring general image…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Hyungtae Lee , Sungmin Eum , Heesung Kwon

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

In this paper, we investigate the problem of overfitting in deep reinforcement learning. Among the most common benchmarks in RL, it is customary to use the same environments for both training and testing. This practice offers relatively…

Machine Learning · Computer Science 2019-07-16 Karl Cobbe , Oleg Klimov , Chris Hesse , Taehoon Kim , John Schulman

The use of Deep Learning (DL) based methods in medical histopathology images have been one of the most sought after solutions to classify, segment, and detect diseased biopsy samples. However, given the complex nature of medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Suvidha Tripathi , Satish Kumar Singh

Learning in deep weight spaces (DWS), where neural networks process the weights of other neural networks, is an emerging research direction, with applications to 2D and 3D neural fields (INRs, NeRFs), as well as making inferences about…

Machine Learning · Computer Science 2024-11-12 Aviv Shamsian , Aviv Navon , David W. Zhang , Yan Zhang , Ethan Fetaya , Gal Chechik , Haggai Maron

Personalizing diffusion models using limited data presents significant challenges, including overfitting, loss of prior knowledge, and degradation of text alignment. Overfitting leads to shifts in the noise prediction distribution,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 JungWoo Chae , Jiyoon Kim , JaeWoong Choi , Kyungyul Kim , Sangheum Hwang

A substantial body of research has focused on developing systems that assist medical professionals during labor-intensive early screening processes, many based on convolutional deep-learning architectures. Recently, multiple studies…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Tristan Piater , Niklas Penzel , Gideon Stein , Joachim Denzler

The accuracy and robustness of image classification with supervised deep learning are dependent on the availability of large-scale, annotated training data. However, there is a paucity of annotated data available due to the complexity of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

Deep learning has revolutionized medical image analysis, playing a vital role in modern clinical applications. However, the deployment of large-scale models in real-world clinical settings remains challenging due to high computational…

Machine Learning · Computer Science 2026-02-03 Cuong Manh Nguyen , Truong-Son Hy

Feature representations from pre-trained deep neural networks have been known to exhibit excellent generalization and utility across a variety of related tasks. Fine-tuning is by far the simplest and most widely used approach that seeks to…

Computer Vision and Pattern Recognition · Computer Science 2017-10-09 Donghyun Yoo , Haoqi Fan , Vishnu Naresh Boddeti , Kris M. Kitani

Deep learning models for survival analysis have gained significant attention in the literature, but they suffer from severe performance deficits when the dataset contains many irrelevant features. We give empirical evidence for this problem…

Machine Learning · Computer Science 2019-03-08 Carl Rietschel , Jinsung Yoon , Mihaela van der Schaar

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

We present a new latent model of natural images that can be learned on large-scale datasets. The learning process provides a latent embedding for every image in the training dataset, as well as a deep convolutional network that maps the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 ShahRukh Athar , Evgeny Burnaev , Victor Lempitsky

Adversarial training is widely used to improve the robustness of deep neural networks to adversarial attack. However, adversarial training is prone to overfitting, and the cause is far from clear. This work sheds light on the mechanisms…

Machine Learning · Computer Science 2022-12-12 Lin Li , Michael Spratling

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Accurately predicting the performance of architecture with small sample training is an important but not easy task. How to analysis and train dataset to overcome overfitting is the core problem we should deal with. Meanwhile if there is the…

Machine Learning · Computer Science 2023-05-04 Ke Zhang

The growing volume of high-resolution Whole Slide Images in digital histopathology poses significant storage, transmission, and computational efficiency challenges. Standard compression methods, such as JPEG, reduce file sizes but often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Srikar Yellapragada , Alexandros Graikos , Kostas Triaridis , Zilinghan Li , Tarak Nath Nandi , Ravi K Madduri , Prateek Prasanna , Joel Saltz , Dimitris Samaras

Excessive reuse of holdout data can lead to overfitting. However, there is little concrete evidence of significant overfitting due to holdout reuse in popular multiclass benchmarks today. Known results show that, in the worst-case,…

Machine Learning · Computer Science 2019-05-27 Vitaly Feldman , Roy Frostig , Moritz Hardt