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The infrequent occurrence of overfit in deep neural networks is perplexing. On the one hand, theory predicts that as models get larger they should eventually become too specialized for a specific training set, with ensuing decrease in…

Machine Learning · Computer Science 2023-12-29 Uri Stern , Daphna Weinshall

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Over-parameterized neural network models often lead to significant performance discrepancies between training and test sets, a phenomenon known as overfitting. To address this, researchers have proposed numerous regularization techniques…

Machine Learning · Computer Science 2025-01-27 RuiZhe Jiang , Haotian Lei

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Histologic examination plays a crucial role in oncology research and diagnostics. The adoption of digital scanning of whole slide images (WSI) has created an opportunity to leverage deep learning-based image classification methods to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Md Zahangir Alom , Quynh T. Tran , Brent A. Orr

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Training a deep learning model to classify histopathological images is challenging, because of the color and shape variability of the cells and tissues, and the reduced amount of available data, which does not allow proper learning of those…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Saypraseuth Mounsaveng , Issam Laradji , David Vázquez , Marco Perdersoli , Ismail Ben Ayed

In the context of medical imaging and machine learning, one of the most pressing challenges is the effective adaptation of pre-trained models to specialized medical contexts. Despite the availability of advanced pre-trained models, their…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Ana Davila , Jacinto Colan , Yasuhisa Hasegawa

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

While previous studies have demonstrated the potential of AI to diagnose diseases in imaging data, clinical implementation is still lagging behind. This is partly because AI models require training with large numbers of examples only…

This paper presents a study on few-shot classification in the context of histopathology images. While few-shot learning has been studied for natural image classification, its application to histopathology is relatively unexplored. Given the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Ardhendu Sekhar , Ravi Kant Gupta , Amit Sethi

Histopathology images are gigapixel-sized and include features and information at different resolutions. Collecting annotations in histopathology requires highly specialized pathologists, making it expensive and time-consuming.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Jin Li , Deepta Rajan , Chintan Shah , Dinkar Juyal , Shreya Chakraborty , Chandan Akiti , Filip Kos , Janani Iyer , Anand Sampat , Ali Behrooz

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

The integration of deep learning based systems in clinical practice is often impeded by challenges rooted in limited and heterogeneous medical datasets. In addition, the field has increasingly prioritized marginal performance gains on a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Sebastian Doerrich , Francesco Di Salvo , Julius Brockmann , Christian Ledig

Deep neural networks demonstrate to have a high performance on image classification tasks while being more difficult to train. Due to the complexity and vanishing gradient problem, it normally takes a lot of time and more computational…

Computer Vision and Pattern Recognition · Computer Science 2018-05-02 Mohammad Sadegh Ebrahimi , Hossein Karkeh Abadi

Adversarial training (AT) with projected gradient descent is the most popular method to improve model robustness under adversarial attacks. However, computational overheads become prohibitively large when AT is applied to large backbone…

Machine Learning · Computer Science 2025-08-26 Quanwei Wu , Jun Guo , Wei Wang , Yi Wang

In software engineering, deep learning models are increasingly deployed for critical tasks such as bug detection and code review. However, overfitting remains a challenge that affects the quality, reliability, and trustworthiness of…

Software Engineering · Computer Science 2024-05-21 Hao Li , Gopi Krishnan Rajbahadur , Dayi Lin , Cor-Paul Bezemer , Zhen Ming , Jiang

The difficulties in both data acquisition and annotation substantially restrict the sample sizes of training datasets for 3D medical imaging applications. As a result, constructing high-performance 3D convolutional neural networks from…

Image and Video Processing · Electrical Eng. & Systems 2022-01-06 Shu Zhang , Zihao Li , Hong-Yu Zhou , Jiechao Ma , Yizhou Yu

Neural network architectures for image demosaicing have been become more and more complex. This results in long training periods of such deep networks and the size of the networks is huge. These two factors prevent practical implementation…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Eric L. Wisotzky , Lara Wallburg , Anna Hilsmann , Peter Eisert , Thomas Wittenberg , Stephan Göb
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