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The influence of initial shape imperfections on the post-buckling and translational behavior of encapsulated microbubbles is investigated subject to acoustic excitation in an unbounded flow. Bifurcation analysis reveals that imperfections…

Fluid Dynamics · Physics 2025-08-26 Maria Vlachomitrou , Georges Chabouh , Alkmini Lytra , Nikos Pelekasis

Traditional surface cleaning methods often suffer from drawbacks such as chemical harshness, potential for surface damage, and high energy consumption. This study investigates an alternative approach: acoustic-driven surface cleaning using…

Soft Condensed Matter · Physics 2025-06-10 Yan Jun Lin , Zhengyang Liu , Sunghwan Jung

Powered by acoustics, existing therapeutic and diagnostic procedures will become less invasive and new methods will become available that have never been available before. Acoustically driven microrobot navigation based on microbubbles is a…

Robotics · Computer Science 2023-08-04 Matthijs Schrage , Mahmoud Medany , Daniel Ahmed

Understanding the shell rheology of ultrasound contrast agent microbubbles is vital for anticipating their bioeffects in clinical practice. Past studies using sophisticated acoustic and optical techniques have made enormous progress in this…

Fluid Dynamics · Physics 2023-08-14 Marco Cattaneo , Outi Supponen

Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…

Medical Physics · Physics 2019-02-07 S. Harput , L. Nie , D. M. J. Cowell , T. Carpenter , B. Raiton , J. McLaughlan , S. Freear

The translation of a bubble under the action of an acoustic forcing finds applications in fields ranging from drug delivery to sonoluminesce. This phenomenon has been widely studied for cases where the amplitude of the forcing remains…

Yield-stress fluids naturally trap small bubbles when their buoyancy applies an insufficient stress to induce local yielding of the material. Under acoustic excitation, trapped bubbles can be driven into volumetric oscillations and apply an…

Soft Condensed Matter · Physics 2020-11-02 Brice Saint-Michel , Valeria Garbin

A variety of numerical methods exist for the study of deformable particles in dense suspensions. None of the standard tools, however, currently include volume-changing objects such as oscillating microbubbles in three-dimensional periodic…

Biological Physics · Physics 2017-08-14 Achim Guckenberger , Stephan Gekle

Direct numerical simulations are utilised to investigate mass transfer processes at gas-evolving electrodes that experience successive formation and detachment of bubbles. The gas-liquid interface is modeled employing an Immersed Boundary…

Fluid Dynamics · Physics 2023-10-23 Farzan Sepahi , Roberto Verzicco , Detlef Lohse , Dominik Krug

Bubbles in complex fluids are often desirable, and sometimes simply inevitable, in the processing of formulated products. Bubbles can rise by buoyancy, grow or dissolve by mass transfer, and readily respond to changes in pressure, thereby…

Fluid Dynamics · Physics 2020-11-02 Brice Saint-Michel , Valeria Garbin

In-body communication is an upcoming field with significant implications for medical diagnostics and therapeutic interventions. Microbubbles have gained attention due to their distinct physical properties, making them promising candidates…

Signal Processing · Electrical Eng. & Systems 2026-03-23 Annika Tjabben , Lea Bergkemper , Carolin Conrad , Michael Gundall , Hans D. Schotten

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

The non-linear dynamics of driven oscillations in the size of a spherical bubble are mapped to the dynamics of a Newtonian particle in a potential within the incompressible liquid regime. The compressible liquid regime, which is important…

Fluid Dynamics · Physics 2024-12-30 Uri Shimon , Ady Stern

Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…

Fluid Dynamics · Physics 2010-10-19 Cheng Wang , Shreyas Jalikop , Sascha Hilgenfeldt

Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of the encapsulated microbubbles under the action of an ultrasound field are…

Soft Condensed Matter · Physics 2018-11-29 Farzan Ghalichi , Sohrab Behnia , Farshad Mottaghi , Mohammad Yahyavi

Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…

Medical Physics · Physics 2022-11-23 Prashant Pandey

We investigate by direct numerical simulations the flow that rising bubbles cause in an originally quiescent fluid. We employ the Eulerian-Lagrangian method with two-way coupling and periodic boundary conditions. In order to be able to…

Fluid Dynamics · Physics 2009-12-29 Irene Mazzitelli , Detlef Lohse

Ultrasound is known to enhance surface bubble growth and removal in catalytic and microfluidic applications, yet the contributions of rectified diffusion and microstreaming phenomena towards mass transfer remain unclear. We quantify the…

We investigate the effect of microbubbles on Taylor-Couette flow by means of direct numerical simulations. We employ an Eulerian-Lagrangian approach with a gas-fluid coupling based on the point-force approximation. Added mass, drag, lift,…

Fluid Dynamics · Physics 2015-06-26 Kazuyasu Sugiyama , Enrico Calzavarini , Detlef Lohse

The spatio-temporal dynamics of separation bubbles induced to form in a fully-developed turbulent boundary layer (with Reynolds number based on momentum thickness of the boundary layer of 490) over a flat plate are studied via direct…

Fluid Dynamics · Physics 2019-12-04 Wen Wu , Charles Meneveau , Rajat Mittal
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