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Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

Machine Learning · Computer Science 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

Populations and Evolution · Quantitative Biology 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

Forecasts of hospitalisations of infectious diseases play an important role for allocating healthcare resources during epidemics and pandemics. Large-scale analysis of model forecasts during the COVID-19 pandemic has shown that the model…

Populations and Evolution · Quantitative Biology 2025-05-20 Grégoire Béchade , Torbjörn Lundh , Philip Gerlee

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

Applications · Statistics 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

The need to forecast COVID-19 related variables continues to be pressing as the epidemic unfolds. Different efforts have been made, with compartmental models in epidemiology and statistical models such as AutoRegressive Integrated Moving…

Applications · Statistics 2020-10-07 Bahman Rostami-Tabar , Juan F. Rendon-Sanchez

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

Machine Learning · Computer Science 2022-07-21 Alexander Rodríguez , Harshavardhan Kamarthi , Pulak Agarwal , Javen Ho , Mira Patel , Suchet Sapre , B. Aditya Prakash

Hospitalisations from COVID-19 with Omicron sub-lineages have put a sustained pressure on the English healthcare system. Understanding the expected healthcare demand enables more effective and timely planning from public health. We collect…

Epidemiological models are an important tool in coping with epidemics, as they offer a forecast, even if often simplistic, of the behavior of the disease in the population. This allows responsible health agencies to organize themselves and…

Populations and Evolution · Quantitative Biology 2023-08-03 Eliza Maria Ferreira , Ricardo Edem Ferreira , Chiara Mocenni

Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…

Physics and Society · Physics 2018-10-11 Samuel V. Scarpino , Giovanni Petri

Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction. The mechanistic structure helps keep trajectories epidemiologically plausible,…

Machine Learning · Computer Science 2026-02-09 Yiqi Su , Ray Lee , Jiaming Cui , Naren Ramakrishnan

The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…

Populations and Evolution · Quantitative Biology 2024-01-15 Marianna Karapitta , Andreas Kasis , Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

The accurate forecasting of infectious epidemic diseases is the key to effective control of the epidemic situation in a region. Most existing methods ignore potential dynamic dependencies between regions or the importance of temporal…

Machine Learning · Computer Science 2022-08-25 Feng Xie , Zhong Zhang , Xuechen Zhao , Bin Zhou , Yusong Tan

Mathematical modeling is one of the key factors of the effective control of newly found infectious diseases, such as COVID-19. Our knowledge about the parameters and the course of the infection is highly limited in the beginning of the…

Quantitative Methods · Quantitative Biology 2021-10-13 Péter Boldog , Norbert Bogya , Zsolt Vizi

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

The worldwide impact of the recent COVID-19 pandemic has been substantial, necessitating the development of accurate forecasting models to predict the spread and course of a pandemic. Previous methods for outbreak forecasting have faced…

Machine Learning · Computer Science 2024-08-28 Ashutosh Anshul , Jhalak Gupta , Mohammad Zia Ur Rehman , Nagendra Kumar

Forecasting influenza like illnesses (ILI) has rapidly progressed in recent years from an art to a science with a plethora of data-driven methods. While these methods have achieved qualified success, their applicability is limited due to…

Machine Learning · Computer Science 2021-01-26 Alexander Rodríguez , Bijaya Adhikari , Naren Ramakrishnan , B. Aditya Prakash

Background: Seasonal influenza causes a substantial burden on healthcare services over the winter period when these systems are already under pressure. Policies during the COVID-19 pandemic supressed the transmission of season influenza,…

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