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Stochastic neural networks are a prototypical computational device able to build a probabilistic representation of an ensemble of external stimuli. Building on the relationship between inference and learning, we derive a synaptic plasticity…
Molecular Communication (MC) channels are characterized by significant memory and nonlinear dynamics arising from diffusion and receptor kinetics. While often viewed as impairments to reliable data transmission, this work introduces a…
The central dogma of molecular biology, formulated more than five decades ago, compartmentalized information exchange in the cell into the DNA, RNA and protein domains. This formalization has served as an implicit thematic distinguisher for…
Cyclic patterns of neuronal activity are ubiquitous in animal nervous systems, and partially responsible for generating and controlling rhythmic movements such as locomotion, respiration, swallowing and so on. Clarifying the role of the…
The cellular Potts model (CPM) is a powerful computational method for simulating collective spatiotemporal dynamics of biological cells. To drive the dynamics, CPMs rely on physics-inspired Hamiltonians. However, as first principles remain…
Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…
Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…
CNNs and computational models of biological vision share some fundamental principles, which opened new avenues of research. However, fruitful cross-field research is hampered by conventional CNN architectures being based on spatially and…
Biological cortical neurons are remarkably sophisticated computational devices, temporally integrating their vast synaptic input over an intricate dendritic tree, subject to complex, nonlinearly interacting internal biological processes. A…
A distributed computing system is a collection of processors that communicate either by reading and writing from a shared memory or by sending messages over some communication network. Most prior biologically inspired distributed computing…
This study introduces EngramNCA, a neural cellular automaton (NCA) that integrates both publicly visible states and private, cell-internal memory channels, drawing inspiration from emerging biological evidence suggesting that memory storage…
A Differentiable Neural Computer (DNC) is a neural network with an external memory which allows for iterative content modification via read, write and delete operations. We show that information theoretic properties of the memory contents…
The Dendritic Cell Algorithm (DCA) as one of the emerging evolutionary algorithms is based on the behavior of the specific immune agents; known as Dendritic Cells (DCs). DCA has several potentially beneficial features for binary…
The advancement of single cell RNA-sequencing technologies has led to an explosion of cell type definitions across multiple organs and organisms. While standards for data and metadata intake are arising, organization of cell types has…
The standard model of memory consolidation foresees that memories are initially recorded in the hippocampus, while features that capture higher-level generalisations of data are created in the cortex, where they are stored for a possibly…
In neuroscience, classical Hopfield networks are the standard biologically plausible model of long-term memory, relying on Hebbian plasticity for storage and attractor dynamics for recall. In contrast, memory-augmented neural networks in…
Biological AI models increasingly predict complex cellular responses, yet their learned representations remain disconnected from the molecular processes they aim to capture. We present CDT-III, which extends mechanism-oriented AI across the…
A cellular non-linear network (CNN) is a uniform regular array of locally connected continuous-state machines, or nodes, which update their states simultaneously in discrete time. A microbial fuel cell (MFC) is an electro-chemical reactor…
In Diffusive Molecular Communication (DMC), information is transmitted by diffusing molecules. Synaptic signaling is a natural implementation of this paradigm. It is responsible for relaying information from one neuron to another, but also…
Humans and most animals inherently possess a distinctive capacity to continually acquire novel experiences and accumulate worldly knowledge over time. This ability, termed continual learning, is also critical for deep neural networks (DNNs)…