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We develop a new computational approach for "focused" optimal Bayesian experimental design with nonlinear models, with the goal of maximizing expected information gain in targeted subsets of model parameters. Our approach considers…

Computation · Statistics 2019-03-28 Chi Feng , Youssef M. Marzouk

Magnetic Resonance Imaging (MRI) acquisitions require extensive scan times, limiting patient throughput and increasing susceptibility to motion artifacts. Accelerated parallel MRI techniques reduce acquisition time by undersampling k-space…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mingi Kang

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

Recent advances in conditional image generation from diffusion models have shown great potential in achieving impressive image quality while preserving the constraints introduced by the user. In particular, ControlNet enables precise…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Hannah Kniesel , Pedro Hermosilla , Timo Ropinski

Magnetic Resonance Imaging (MRI) plays a vital role in diagnosis, management and monitoring of many diseases. However, it is an inherently slow imaging technique. Over the last 20 years, parallel imaging, temporal encoding and compressed…

In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs. These experiments are expensive, so one might hope to reduce their cost by only experimenting on a…

Machine Learning · Computer Science 2025-04-15 Ihor Neporozhnii , Julien Roy , Emmanuel Bengio , Jason Hartford

Deep generative models have been studied and developed primarily in the context of natural images and computer vision. This has spurred the development of (Bayesian) methods that use these generative models for inverse problems in image…

Signal Processing · Electrical Eng. & Systems 2025-04-17 Tristan S. W. Stevens , Jeroen Overdevest , Oisín Nolan , Wessel L. van Nierop , Ruud J. G. van Sloun , Yonina C. Eldar

Accelerated MRI shortens acquisition time by subsampling in the measurement $\kappa$-space. Recovering a high-fidelity anatomical image from subsampled measurements requires close cooperation between two components: (1) a sampler that…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Tianwei Yin , Zihui Wu , He Sun , Adrian V. Dalca , Yisong Yue , Katherine L. Bouman

Fine-tuning-based adaptation is widely used to customize diffusion-based image generation, leading to large collections of community-created adapters that capture diverse subjects and styles. Adapters derived from the same base model can be…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Chenxi Liu , Selena Ling , Alec Jacobson

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

In medical imaging, generative models are increasingly relied upon for two distinct but equally critical tasks: reconstruction, where the goal is to restore medical imaging (usually inverse problems like inpainting or superresolution), and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Niklas Bubeck , Yundi Zhang , Suprosanna Shit , Daniel Rueckert , Jiazhen Pan

This paper presents novel single and multi-shell sampling schemes for diffusion MRI. In diffusion MRI, it is paramount that the number of samples is as small as possible in order that scan times are practical in a clinical setting. The…

Signal Processing · Electrical Eng. & Systems 2019-02-01 Alice P. Bates , Zubair Khalid , Jason D. McEwen , Rodney A. Kennedy , Alessandro Daducci , Erick J. Canales-Rodríguez

Bayesian optimal experimental design (OED) seeks to conduct the most informative experiment under budget constraints to update the prior knowledge of a system to its posterior from the experimental data in a Bayesian framework. Such…

Machine Learning · Computer Science 2024-02-29 Rafael Orozco , Felix J. Herrmann , Peng Chen

Learning-based synthetic multi-contrast MRI commonly involves deep models trained using high-quality images of source and target contrasts, regardless of whether source and target domain samples are paired or unpaired. This results in…

Image and Video Processing · Electrical Eng. & Systems 2021-05-13 Mahmut Yurt , Salman Ul Hassan Dar , Muzaffer Özbey , Berk Tınaz , Kader Karlı Oğuz , Tolga Çukur

Data collected from arrays of sensors are essential for informed decision-making in various systems. However, the presence of anomalies can compromise the accuracy and reliability of insights drawn from the collected data or information…

Applications · Statistics 2024-03-19 Katie Buchhorn , Kerrie Mengersen , Edgar Santos-Fernandez , James McGree

Ultrafast electron diffraction using MeV energy beams(MeV-UED) has enabled unprecedented scientific opportunities in the study of ultrafast structural dynamics in a variety of gas, liquid and solid state systems. Broad scientific…

Fast Magnetic Resonance Imaging (MRI) is highly in demand for many clinical applications in order to reduce the scanning cost and improve the patient experience. This can also potentially increase the image quality by reducing the motion…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Simiao Yu , Hao Dong , Guang Yang , Greg Slabaugh , Pier Luigi Dragotti , Xujiong Ye , Fangde Liu , Simon Arridge , Jennifer Keegan , David Firmin , Yike Guo

Low-field magnetic resonance imaging (MRI) offers affordable access to diagnostic imaging but faces challenges such as prolonged acquisition times and reduced image quality. Although accelerated imaging via k-space undersampling helps…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Daniel Tweneboah Anyimadu , Mohammed M. Abdelsamea , Ahmed Karam Eldaly

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan

Mapping white matter tracts is an essential step towards understanding brain function. Diffusion Magnetic Resonance Imaging (dMRI) is the only noninvasive technique which can detect in vivo anisotropies in the 3-dimensional diffusion of…

Computation · Statistics 2014-03-21 Dario Gasbarra , Jia Liu , Juha Railavo