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In this paper, we evaluate the portability of the SYCL programming model on some of the latest CPUs and GPUs from a wide range of vendors, utilizing the two main compilers: DPC++ and hipSYCL/OpenSYCL. Both compilers currently support GPUs…

Performance · Computer Science 2023-09-20 Istvan Z Reguly

The accurate sampling of protein dynamics is an ongoing challenge despite the utilization of High-Performance Computers (HPC) systems. Utilizing only "brute force" MD simulations requires an unacceptably long time to solution. Adaptive…

Quantitative Methods · Quantitative Biology 2020-09-25 Eugen Hruska , Vivekanandan Balasubramanian , Hyungro Lee , Shantenu Jha , Cecilia Clementi

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

High Performance Computing (HPC) platforms allow scientists to model computationally intensive algorithms. HPC clusters increasingly use General-Purpose Graphics Processing Units (GPGPUs) as accelerators; FPGAs provide an attractive…

Hardware Architecture · Computer Science 2015-04-20 Syed Waqar Nabi , Saji N. Hameed , Wim Vanderbauwhede

High Performance Computing (HPC) aims at providing reasonably fast computing solutions to scientific and real life problems. The advent of multicore architectures is noticeable in the HPC history, because it has brought the underlying…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-07 Claude Tadonki

We introduce Arbor, a performance portable library for simulation of large networks of multi-compartment neurons on HPC systems. Arbor is open source software, developed under the auspices of the HBP. The performance portability is by…

Neurons and Cognition · Quantitative Biology 2019-04-12 Nora Abi Akar , Ben Cumming , Vasileios Karakasis , Anne Küsters , Wouter Klijn , Alexander Peyser , Stuart Yates

In our former works we have made serious efforts to improve the performance of medical image analysis methods with using ensemble-based systems. In this paper, we present a novel hardware-based solution for the efficient adoption of our…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Laszlo Kovacs , Roland Kovacs , Andras Hajdu

Bloom filters are a fundamental data structure for approximate membership queries, with applications ranging from data analytics to databases and genomics. Several variants have been proposed to accommodate parallel architectures. GPUs,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-18 Daniel Jünger , Kevin Kristensen , Yunsong Wang , Xiangyao Yu , Bertil Schmidt

When considering different hardware platforms, not just the time-to-solution can be of importance but also the energy necessary to reach it. This is not only the case with battery powered and mobile devices but also with high-performance…

Performance · Computer Science 2020-06-30 Philip Heinisch , Katharina Ostaszewski , Hendrik Ranocha

The pace of improvement in the performance of conventional computer hardware has slowed significantly during the past decade, largely as a consequence of reaching the physical limits of manufacturing processes. To offset this slowdown, new…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-16 Marc P. Armstrong

Open source bioinformatics tools running under MS Windows are rare to find, and those running under Windows HPC cluster are almost non-existing. This is despite the fact that the Windows is the most popular operating system used among life…

Mathematical Software · Computer Science 2009-05-06 Mohamed Abouelhoda , Hisham Mohamed

Particle-in-Cell (PIC) Monte Carlo (MC) simulations are central to plasma physics but face increasing challenges on heterogeneous HPC systems due to excessive data movement, synchronization overheads, and inefficient utilization of multiple…

This paper discusses the challenges encountered when analyzing the energy efficiency of synthetic benchmarks and the Gromacs package on the Fritz and Alex HPC clusters. Experiments were conducted using MPI parallelism on full sockets of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-04 Rafael Ravedutti Lucio Machado , Jan Eitzinger , Georg Hager , Gerhard Wellein

The rapid growth of deep learning has driven exponential increases in model parameters and computational demands. NVIDIA GPUs and their CUDA-based software ecosystem provide robust support for parallel computing, significantly alleviating…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-08 Jiaqi Lv , Xufeng He , Yanchen Liu , Xu Dai , Aocheng Shen , Yinghao Li , Jiachen Hao , Jianrong Ding , Yang Hu , Shouyi Yin

GPUs are the most popular platform for accelerating HPC workloads, such as artificial intelligence and science simulations. However, most microarchitectural research in academia relies on GPU core pipeline designs based on architectures…

Hardware Architecture · Computer Science 2025-10-30 Rodrigo Huerta , Mojtaba Abaie Shoushtary , José-Lorenzo Cruz , Antonio González

A parallel code has been written in FORTRAN90, C, and MPI for the analysis of biological simulation data. Using a master/slave algorithm, the software operates on AMBER generated trajectory data using either UNIX or MPI file IO, and it…

Computational Physics · Physics 2008-08-25 David N. Lebard

Computational Fluid Dynamics (CFD) is the simulation of fluid flow undertaken with the use of computational hardware. The underlying equations are computationally challenging to solve and necessitate high performance computing (HPC) to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-04 Zachary Cooper-Baldock , Brenda Vara Almirall , Kiao Inthavong

Modern multi GPU HPC systems expose substantial computational capacity, yet inefficient GPU allocation often leads to wasted energy and underutilization. In practice, GPU applications exhibit heterogeneous and nonlinear scaling, making it…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-21 Zhong Zheng , Michael E. Papka , Zhiling Lan

Due to their highly parallel multi-cores architecture, GPUs are being increasingly used in a wide range of computationally intensive applications. Compared to CPUs, GPUs can achieve higher performances at accelerating the programs'…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-05 Frédéric Magoulès , Abal-Kassim Cheik Ahamed , Alban Desmaison , Jean-Christophe Léchenet , François Mayer , Haifa Ben Salem , Thomas Zhu

Hardware accelerators such as Graphics Processing Units (GPUs), Intel Xeon Phi co-processors (PHIs), and Field-Programmable Gate Arrays (FPGAs) are now ubiquitous in extreme-scale high performance computing (HPC), cloud, and Big data…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-16 Daniel Hanlon , Hamidreza Khalighzadeh , Ravi Reddy Manumachu , Alexey Lastovetsky
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