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Late gadolinium enhancement (LGE) imaging is the clinical standard for myocardial scar assessment, but limited annotated datasets hinder the development of automated segmentation methods. We propose a novel framework that synthesises both…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Soufiane Ben Haddou , Laura Alvarez-Florez , Erik J. Bekkers , Fleur V. Y. Tjong , Ahmad S. Amin , Connie R. Bezzina , Ivana Išgum

Identification and quantification of myocardial scar is important for diagnosis and prognosis of cardiovascular diseases. However, reliable scar segmentation from Late Gadolinium Enhancement Cardiac Magnetic Resonance (LGE-CMR) images…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Nivetha Jayakumar , Jonathan Pan , Shuo Wang , Bishow Paudel , Nisha Hosadurg , Cristiane C. Singulane , Sivam Bhatt , Amit R. Patel , Miaomiao Zhang

Visualizing disease-induced scarring and fibrosis in the heart on cardiac magnetic resonance (CMR) imaging with contrast enhancement (LGE) is paramount in characterizing disease progression and quantifying pathophysiological substrates of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Haley G. Abramson , Dan M. Popescu , Rebecca Yu , Changxin Lai , Julie K. Shade , Katherine C. Wu , Mauro Maggioni , Natalia A. Trayanova

Accurate segmentation of the cardiac boundaries in late gadolinium enhancement magnetic resonance images (LGE-MRI) is a fundamental step for accurate quantification of scar tissue. However, while there are many solutions for automatic…

Image and Video Processing · Electrical Eng. & Systems 2020-01-14 Víctor M. Campello , Carlos Martín-Isla , Cristian Izquierdo , Steffen E. Petersen , Miguel A. González Ballester , Karim Lekadir

Segmentation of cardiac fibrosis and scar are essential for clinical diagnosis and can provide invaluable guidance for the treatment of cardiac diseases. Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been…

Image and Video Processing · Electrical Eng. & Systems 2021-07-01 Yinzhe Wu , Zeyu Tang , Binghuan Li , David Firmin , Guang Yang

Accurate segmentation of myocardial scar from late gadolinium enhanced (LGE) cardiac MRI is essential for evaluating tissue viability, yet remains challenging due to variable contrast and imaging artifacts. Electrocardiogram (ECG) signals…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Farheen Ramzan , Yusuf Kiberu , Nikesh Jathanna , Meryem Jabrane , Vicente Grau , Shahnaz Jamil-Copley , Richard H. Clayton , Chen , Chen

Accurate cardiac computing, analysis and modeling from multi-modality images are important for the diagnosis and treatment of cardiac disease. Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is a promising technique to…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Lei Li , Fuping Wu , Sihang Wang , Xiahai Zhuang

Segmentation of enhancement in LGE cardiac MRI is critical for diagnosing various ischemic and non-ischemic cardiomyopathies. However, creating pixel-level annotations for these images is challenging and labor-intensive, leading to limited…

Artificial Intelligence · Computer Science 2026-03-20 Athira J. Jacob , Puneet Sharma , Daniel Rueckert

Automated identification of myocardial scar from late gadolinium enhancement cardiac magnetic resonance images (LGE-CMR) is limited by image noise and artifacts such as those related to motion and partial volume effect. This paper presents…

Image and Video Processing · Electrical Eng. & Systems 2022-11-14 Jiarui Xing , Shuo Wang , Kenneth C. Bilchick , Amit R. Patel , Miaomiao Zhang

Late gadolinium enhancement MRI (LGE MRI) is the gold standard for the detection of myocardial scars for post myocardial infarction (MI). LGE MRI requires the injection of a contrast agent, which carries potential side effects and increases…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Guang Yang , Jingkun Chen , Xicheng Sheng , Shan Yang , Xiahai Zhuang , Betty Raman , Lei Li , Vicente Grau

Background: The clinical utility of late gadolinium enhancement (LGE) cardiac MRI is limited by the lack of standardization, and time-consuming postprocessing. In this work, we tested the hypothesis that a cascaded deep learning pipeline…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Didier R. P. R. M. Lustermans , Sina Amirrajab , Mitko Veta , Marcel Breeuwer , Cian M. Scannell

Background: Late Gadolinium Enhancement (LGE) imaging is the gold standard for assessing myocardial fibrosis and scarring, with left ventricular (LV) LGE extent predicting major adverse cardiac events (MACE). Despite its importance, routine…

Cardiac MRI late gadolinium enhancement (LGE) enables non-invasive identification of left atrial (LA) scar, whose spatial distribution is strongly associated with atrial fibrillation (AF) severity and recurrence. However, automatic LA scar…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Jing Zhang , Bastien Bergere , Emilie Bollache , Jonas Leite , Mikaël Laredo , Alban Redheuil , Nadjia Kachenoura

Myocardium segmentation of late gadolinium enhancement (LGE) Cardiac MR images is important for evaluation of infarction regions in clinical practice. The pathological myocardium in LGE images presents distinctive brightness and textures…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Xumin Tao , Hongrong Wei , Wufeng Xue , Dong Ni

Late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) can directly visualize nonviable myocardium with hyperenhanced intensities with respect to normal myocardium. For heart attack patients, it is crucial to facilitate the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 Dong Wei , Ying Sun , Sim-Heng Ong , Ping Chai , Lynette L Teo , Adrian F Low

Automatic segmentation of myocardium in Late Gadolinium Enhanced (LGE) Cardiac MR (CMR) images is often difficult due to the intensity heterogeneity resulting from accumulation of contrast agent in infarcted areas. In this paper, we propose…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 Dong Wei , Ying Sun , Ping Chai , Adrian Low , Sim Heng Ong

Significance: Late gadolinium enhanced magnetic resonance imaging (LGE-MRI) is the gold standard technique for myocardial viability assessment. Although the technique accurately reflects the damaged tissue, there is no clinical standard for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-27 Ezequiel de la Rosa , Désiré Sidibé , Thomas Decourselle , Thibault Leclercq , Alexandre Cochet , Alain Lalande

Late gadolinium enhanced (LGE) magnetic resonance (MR) imaging is widely established to assess the viability of myocardial tissue of patients after acute myocardial infarction (MI). We propose the Cascading Refinement CNN (CaRe-CNN), which…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Franz Thaler , Matthias A. F. Gsell , Gernot Plank , Martin Urschler

Detection of hyperenhancement from cardiac LGE MRI images is a complex task requiring significant clinical expertise. Although deep learning-based models have shown promising results for the task, they require large amounts of data with…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Athira J Jacob , Puneet Sharma , Daniel Rueckert

Myocardial infarction (MI) is one of the most prevalent cardiovascular diseases and consequently, a major cause for mortality and morbidity worldwide. Accurate assessment of myocardial tissue viability for post-MI patients is critical for…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler
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