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This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…

Cryptography and Security · Computer Science 2024-10-29 David Noever

As large language models (LLMs) are increasingly integrated into daily life, in roles ranging from high-stakes decision support to companionship, understanding their behavioral dispositions becomes critical. A growing literature uses…

Artificial Intelligence · Computer Science 2026-04-22 Valentin Kriegmair , Dirk U. Wulff

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

Computation and Language · Computer Science 2025-11-17 Arsh Gupta , Ajay Narayanan Sridhar , Bonam Mingole , Amulya Yadav

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

While large language models (LLMs) excel in mathematical and code reasoning, we observe they struggle with social reasoning tasks, exhibiting cognitive confusion, logical inconsistencies, and conflation between objective world states and…

Computation and Language · Computer Science 2025-10-14 Jialu Du , Guiyang Hou , Yihui Fu , Chen Wu , Wenqi Zhang , Yongliang Shen , Weiming Lu

Large language models (LLMs) are increasingly used to support the analysis of complex financial disclosures, yet their reliability, behavioral consistency, and transparency remain insufficiently understood in high-stakes settings. This…

Computation and Language · Computer Science 2026-01-21 Md Talha Mohsin

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

Computation and Language · Computer Science 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

The growing interest in vision-language models (VLMs) has been driven by improvements in large language models and vision transformers. Despite the abundance of literature on this subject, we observe that critical decisions regarding the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Hugo Laurençon , Léo Tronchon , Matthieu Cord , Victor Sanh

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

Sensitivity analysis methods such as the Cornfield inequality and the E-value were developed to assess the robustness of observed associations against unmeasured confounding -- a major challenge in observational studies. However, the…

Other Statistics · Statistics 2026-04-10 Qingyan Xiang , Jiahao Zhang , Bojian Feng

Large language models have increasingly been proposed as a powerful replacement for classical agent-based models (ABMs) to simulate social dynamics. By using LLMs as a proxy for human behavior, the hope of this new approach is to be able to…

Computers and Society · Computer Science 2024-12-09 Da Ju , Adina Williams , Brian Karrer , Maximilian Nickel

Vision-language models (VLMs) are increasingly proposed for clinical decision support, yet their reliability in real-world scenarios that require integrating both visual and textual context from medical records remains poorly characterized.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

Artificial Intelligence · Computer Science 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen

Large Vision Language Models (LVLMs) have recently achieved superior performance in various tasks on natural image and text data, which inspires a large amount of studies for LVLMs fine-tuning and training. Despite their advancements, there…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zishan Gu , Changchang Yin , Fenglin Liu , Ping Zhang

Large Language Models have revolutionized various fields and industries, such as Conversational AI, Content Generation, Information Retrieval, Business Intelligence, and Medical, to name a few. One major application in the field of medical…

Computation and Language · Computer Science 2024-02-06 Ata Mustafa

The emergence of Large Language Models (LLMs) has driven rapid progress in multi-modal learning, particularly in the development of Large Vision-Language Models (LVLMs). However, existing LVLM training paradigms place excessive reliance on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kaihua Tang , Jiaxin Qi , Jinli Ou , Yuhua Zheng , Jianqiang Huang

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

This paper systematically examines nation-level biases exhibited by Large Language Models (LLMs) within the domain of International Relations (IR). Leveraging historical records from the United Nations Security Council (UNSC), we developed…

Computation and Language · Computer Science 2025-12-02 Jonghyeon Choi , Yeonjun Choi , Hyun-chul Kim , Beakcheol Jang
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