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The complete blood count (CBC) performed by automated hematology analyzers is one of the most ordered laboratory tests. It is a first-line tool for assessing a patient's general health status, or diagnosing and monitoring disease…

Machine Learning · Statistics 2020-11-25 Marta Avalos-Fernandez , Helene Touchais , Marcela Henriquez-Henriquez

Blood lactate concentration is a strong indicator of mortality risk in critically ill patients. While frequent lactate measurements are necessary to assess patient's health state, the measurement is an invasive procedure that can increase…

Machine Learning · Computer Science 2019-10-04 Behrooz Mamandipoor , Mahshid Majd , Monica Moz , Venet Osmani

Medical benchmark datasets significantly contribute to developing Large Language Models (LLMs) for medical knowledge extraction, diagnosis, summarization, and other uses. Yet, current benchmarks are mainly derived from exam questions given…

Computation and Language · Computer Science 2025-03-11 Oriel Perets , Ofir Ben Shoham , Nir Grinberg , Nadav Rappoport

We investigate the longitudinal behaviour of blood markers from common haematological tests as a marker of disease and as a function of disease progression in a variety of conditions including cancer, cardiovascular disease, and infections.…

Quantitative Methods · Quantitative Biology 2026-04-21 Riya Nagar , Abicumaran Uthamacumaran , Adelaide de Vecchi , Hector Zenil

Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Rachel Lea Draelos , David Dov , Maciej A. Mazurowski , Joseph Y. Lo , Ricardo Henao , Geoffrey D. Rubin , Lawrence Carin

Chest X-ray (CXR) is the most common X-ray examination performed in daily clinical practice for the diagnosis of various heart and lung abnormalities. The large amount of data to be read and reported, with 100+ studies per day for a single…

Computer Vision and Pattern Recognition · Computer Science 2019-05-17 Sebastian Guendel , Florin C. Ghesu , Sasa Grbic , Eli Gibson , Bogdan Georgescu , Andreas Maier , Dorin Comaniciu

CXRs are a crucial and extraordinarily common diagnostic tool, leading to heavy research for CAD solutions. However, both high classification accuracy and meaningful model predictions that respect and incorporate clinical taxonomies are…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Haomin Chen , Shun Miao , Daguang Xu , Gregory D. Hager , Adam P. Harrison

Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training. Unfortunately, many prior anomaly detection methods…

This study investigates the feasibility of using electrocardiogram (ECG) data combined with basic patient metadata to estimate and monitor prompt laboratory abnormalities. We use the MIMIC-IV dataset to train multimodal deep learning models…

Signal Processing · Electrical Eng. & Systems 2025-11-20 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Tabular medical records remain the most readily available data format for applying machine learning in healthcare. However, traditional data preprocessing ignores valuable contextual information in tables and requires substantial manual…

Lab tests are fundamental for diagnosing diseases and monitoring patient conditions. However, frequent testing can be burdensome for patients, and test results may not always be immediately available. To address these challenges, we propose…

Machine Learning · Computer Science 2025-07-08 Sujeong Im , Jungwoo Oh , Edward Choi

Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…

Signal Processing · Electrical Eng. & Systems 2019-01-11 Deepta Rajan , David Beymer , Girish Narayan

Although there have been several recent advances in the application of deep learning algorithms to chest x-ray interpretation, we identify three major challenges for the translation of chest x-ray algorithms to the clinical setting. We…

Image and Video Processing · Electrical Eng. & Systems 2020-03-12 Pranav Rajpurkar , Anirudh Joshi , Anuj Pareek , Phil Chen , Amirhossein Kiani , Jeremy Irvin , Andrew Y. Ng , Matthew P. Lungren

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Tables are an abundant form of data with use cases across all scientific fields. Real-world datasets often contain anomalous samples that can negatively affect downstream analysis. In this work, we only assume access to contaminated data…

Machine Learning · Computer Science 2023-07-25 Guy Zamberg , Moshe Salhov , Ofir Lindenbaum , Amir Averbuch

Background: External validations are essential to assess clinical prediction models (CPMs) before deployment. Apart from model misspecification, differences in patient population and other factors influence a model's AUC (c-statistic). We…

Estimating the maximum mean finds a variety of applications in practice. In this paper, we study estimation of the maximum mean using an upper confidence bound (UCB) approach where the sampling budget is adaptively allocated to one of the…

Statistics Theory · Mathematics 2024-08-09 Zhang Kun , Liu Guangwu , Shi Wen

Medical anomaly detection has emerged as a promising solution to challenges in data availability and labeling constraints. Traditional methods extract features from different layers of pre-trained networks in Euclidean space; however,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Alvaro Gonzalez-Jimenez , Simone Lionetti , Ludovic Amruthalingam , Philippe Gottfrois , Fabian Gröger , Marc Pouly , Alexander A. Navarini

Background: Medical decision-making impacts both individual and public health. Clinical scores are commonly used among a wide variety of decision-making models for determining the degree of disease deterioration at the bedside. AutoScore…

Recognizing the types of white blood cells (WBCs) in microscopic images of human blood smears is a fundamental task in the fields of pathology and hematology. Although previous studies have made significant contributions to the development…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Satoshi Tsutsui , Zhengyang Su , Bihan Wen
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