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Marginal structural models are a popular tool for investigating the effects of time-varying treatments, but they require an assumption of no unobserved confounders between the treatment and outcome. With observational data, this assumption…

Methodology · Statistics 2021-06-10 Matthew Blackwell , Soichiro Yamauchi

Generalization methods offer a powerful solution to one of the key drawbacks of randomized controlled trials (RCTs): their limited representativeness. By enabling the transport of treatment effect estimates to target populations subject to…

Methodology · Statistics 2025-05-20 Ahmed Boughdiri , Clément Berenfeld , Julie Josse , Erwan Scornet

As meta-analysis of multiple diagnostic tests impacts clinical decision making and patient health, there is growing interest in statistical models that synthesize evidence from studies comparing multiple diagnostic tests. To compare the…

Methodology · Statistics 2026-05-19 Aristidis K. Nikoloulopoulos

Purpose: Prenatal ultrasound is a key tool in evaluating fetal structural development and detecting abnormalities, contributing to reduced perinatal complications and improved neonatal survival. Accurate identification of standard fetal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shengjun Zhu , Siyu Liu , Runqing Xiong , Liping Zheng , Duo Ma , Rongshang Chen , Jiaxin Cai

Markov decision processes (MDPs) are used to model a wide variety of applications ranging from game playing over robotics to finance. Their optimal policy typically maximizes the expected sum of rewards given at each step of the decision…

Machine Learning · Computer Science 2025-05-26 Maximilian Nägele , Jan Olle , Thomas Fösel , Remmy Zen , Florian Marquardt

Consider testing multiple hypotheses using tests that can only be evaluated by simulation, such as permutation tests or bootstrap tests. This article introduces MMCTest, a sequential algorithm which gives, with arbitrarily high probability,…

Methodology · Statistics 2018-10-17 Axel Gandy , Georg Hahn

Contextual Markov decision processes (CMDPs) describe a class of reinforcement learning problems in which the transition kernels and reward functions can change over time with different MDPs indexed by a context variable. While CMDPs serve…

Machine Learning · Computer Science 2024-02-06 Junze Deng , Yuan Cheng , Shaofeng Zou , Yingbin Liang

Distribution shift is a common challenge in medical images obtained from different clinical centers, significantly hindering the deployment of pre-trained semantic segmentation models in real-world applications across multiple domains.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Lingrui Li , Yanfeng Zhou , Nan Pu , Xin Chen , Zhun Zhong

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during…

Neurons and Cognition · Quantitative Biology 2025-06-24 Shervin Safavi , Danaé Rolland , Philipp Sterzer , Renaud Jardri , Pantelis Leptourgos

Multimodal sentiment analysis (MSA) aims to understand human emotions by integrating information from multiple modalities, such as text, audio, and visual data. However, existing methods often suffer from spurious correlations both within…

Machine Learning · Computer Science 2026-05-21 Menghua Jiang , Yuxia Lin , Baoliang Chen , Haifeng Hu , Yuncheng Jiang , Sijie Mai

Estimating an individual's potential outcomes under counterfactual treatments is a challenging task for traditional causal inference and supervised learning approaches when the outcome is high-dimensional (e.g. gene expressions, impulse…

Machine Learning · Statistics 2025-02-13 Yulun Wu , Layne C. Price , Zichen Wang , Vassilis N. Ioannidis , Robert A. Barton , George Karypis

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

Methodology · Statistics 2026-03-03 Harlan Campbell , Jeroen P. Jansen

Causal or unconfounded descriptive comparisons between multiple groups are common in observational studies. Motivated from a racial disparity study in health services research, we propose a unified propensity score weighting framework, the…

Methodology · Statistics 2019-07-10 Fan Li , Fan Li

Learning an effective representation in multi-label text classification (MLTC) is a significant challenge in NLP. This challenge arises from the inherent complexity of the task, which is shaped by two key factors: the intricate connections…

Machine Learning · Computer Science 2024-04-16 Alexandre Audibert , Aurélien Gauffre , Massih-Reza Amini

For the outcomes and phenotypes of complex diseases, multiple types of molecular (genetic, genomic, epigenetic, etc.) changes, environmental risk factors, and their interactions have been found to have important contributions. In each of…

Methodology · Statistics 2019-12-19 Yaqing Xu , Mengyun Wu , Shuangge Ma

Statistical machine learning often uses probabilistic algorithms, such as Markov Chain Monte Carlo (MCMC), to solve a wide range of problems. Probabilistic computations, often considered too slow on conventional processors, can be…

Signal Processing · Electrical Eng. & Systems 2020-03-26 Xiangyu Zhang , Ramin Bashizade , Yicheng Wang , Cheng Lyu , Sayan Mukherjee , Alvin R. Lebeck

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

Methodology · Statistics 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

With the advent of ubiquitous monitoring and measurement protocols, studies have started to focus more and more on complex, multivariate and heterogeneous datasets. In such studies, multivariate response variables are drawn from a…

Methodology · Statistics 2023-03-03 Saverio Ranciati , Veronica Vinciotti , Ernst C. Wit , Giuliano Galimberti

Genome-wide Association Studies (GWASs) for complex diseases often collect data on multiple correlated endo-phenotypes. Multivariate analysis of these correlated phenotypes can improve the power to detect genetic variants. Multivariate…

Methodology · Statistics 2015-03-12 Debashree Ray , James S Pankow , Saonli Basu

This article discusses $A$-, $D$- and $E$-optimality results for multivariate crossover designs, where more than one response is measured from every period for each subject. The motivation for these multivariate designs comes from a $3…

Methodology · Statistics 2025-09-22 Shubham Niphadkar , Siuli Mukhopadhyay