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Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

Different medical imaging modalities capture diagnostic information at varying spatial resolutions, from coarse global patterns to fine-grained localized structures. However, most existing vision-language frameworks in the medical domain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Shivang Chopra , Gabriela Sanchez-Rodriguez , Lingchao Mao , Andrew J Feola , Jing Li , Zsolt Kira

Clinical decision-making reflects diverse strategies shaped by regional patient populations and institutional protocols. However, most existing medical artificial intelligence (AI) models are trained on highly prevalent data patterns, which…

The long-term progression of neurodegenerative diseases is commonly conceptualized as a spatiotemporal diffusion process that consists of a graph diffusion process across the structural brain connectome and a localized reaction process…

Machine Learning · Computer Science 2025-08-12 Tiantian He , Keyue Jiang , An Zhao , Anna Schroder , Elinor Thompson , Sonja Soskic , Frederik Barkhof , Daniel C. Alexander

Dimensionality reduction (DR) plays a crucial role in various fields, including data engineering and visualization, by simplifying complex datasets while retaining essential information. However, achieving both high DR accuracy and strong…

Machine Learning · Computer Science 2025-07-01 Zelin Zang , Yuhao Wang , Jinlin Wu , Hong Liu , Yue Shen , Zhen Lei , Stan. Z Li

Dense Retrieval Models (DRMs) are a prominent development in Information Retrieval (IR). A key challenge with these neural Transformer-based models is that they often struggle to generalize beyond the specific tasks and domains they were…

Information Retrieval · Computer Science 2025-10-20 Effrosyni Sokli , Pranav Kasela , Georgios Peikos , Gabriella Pasi

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Modern applications increasingly involve many heterogeneous input streams, such as clinical sensors, wearable device data, imaging, and text, each with distinct measurement models, sampling rates, and noise characteristics. We define this…

Machine Learning · Computer Science 2026-03-03 Xing Han , Hsing-Huan Chung , Joydeep Ghosh , Paul Pu Liang , Suchi Saria

Mixture-of-Experts (MoE) architectures achieve scalable learning by routing inputs to specialized subnetworks through conditional computation. However, conventional MoE designs assume homogeneous expert capability and domain-agnostic…

Neural operators have emerged as an efficient paradigm for solving PDEs, overcoming the limitations of traditional numerical methods and significantly improving computational efficiency. However, due to the diversity and complexity of PDE…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Dengdi Sun , Xiaoya Zhou , Xiao Wang , Hao Si , Wanli Lyu , Jin Tang , Bin Luo

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Yitong Li , Morteza Ghahremani , Youssef Wally , Christian Wachinger

Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Guoxin Wang , Xuyang Cao , Shan An , Fengmei Fan , Chao Zhang , Jinsong Wang , Feng Yu , Zhiren Wang

Graph neural networks excel at graph representation learning but struggle with heterophilous data and long-range dependencies. And graph transformers address these issues through self-attention, yet face scalability and noise challenges on…

Machine Learning · Computer Science 2025-02-13 Xuanze Chen , Jiajun Zhou , Shanqing Yu , Qi Xuan

In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Arghavan Rezvani , Xiangyi Yan , Anthony T. Wu , Kun Han , Pooya Khosravi , Xiaohui Xie

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Mixture-of-Experts (MoE) architectures have emerged as a powerful paradigm for scaling neural networks while maintaining computational efficiency. However, standard MoE implementations rely on two rigid design assumptions: (1) fixed Top-K…

Machine Learning · Computer Science 2026-03-03 Gökdeniz Gülmez

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken
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