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Masked Diffusion Models (MDMs) have emerged as one of the most promising paradigms for generative modeling over discrete domains. It is known that MDMs effectively train to decode tokens in a random order, and that this ordering has…

Machine Learning · Computer Science 2025-11-25 Prateek Garg , Bhavya Kohli , Sunita Sarawagi

We present Masked Frequency Modeling (MFM), a unified frequency-domain-based approach for self-supervised pre-training of visual models. Instead of randomly inserting mask tokens to the input embeddings in the spatial domain, in this paper,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Jiahao Xie , Wei Li , Xiaohang Zhan , Ziwei Liu , Yew Soon Ong , Chen Change Loy

Successful methods for unsupervised neural machine translation (UNMT) employ crosslingual pretraining via self-supervision, often in the form of a masked language modeling or a sequence generation task, which requires the model to align the…

Computation and Language · Computer Science 2021-04-15 Alexandra Chronopoulou , Dario Stojanovski , Alexander Fraser

Unsupervised text embeddings extraction is crucial for text understanding in machine learning. Word2Vec and its variants have received substantial success in mapping words with similar syntactic or semantic meaning to vectors close to each…

Computation and Language · Computer Science 2018-05-30 Furong Huang , Animashree Anandkumar

Single-cell RNA sequencing (scRNA-seq) enables single-cell transcriptomic profiling, revealing cellular heterogeneity and rare populations. Recent deep learning models like Geneformer and Mouse-Geneformer perform well on tasks such as…

Genomics · Quantitative Biology 2025-07-11 Yuki Nishio , Takayoshi Yamashita , Keita Ito , Tsubasa Hirakawa , Hironobu Fujiyoshi

In text-to-SQL task, seq-to-seq models often lead to sub-optimal performance due to limitations in their architecture. In this paper, we present a simple yet effective approach that adapts transformer-based seq-to-seq model to robust…

Computation and Language · Computer Science 2023-01-31 Kuan Xu , Yongbo Wang , Yongliang Wang , Zujie Wen , Yang Dong

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Wearable foundation models (WFMs), trained on large volumes of data collected by affordable, always-on devices, have demonstrated strong performance on short-term, well-defined health monitoring tasks, including activity recognition,…

Machine Learning · Computer Science 2026-03-23 Yu Yvonne Wu , Yuwei Zhang , Hyungjun Yoon , Ting Dang , Dimitris Spathis , Tong Xia , Qiang Yang , Jing Han , Dong Ma , Sung-Ju Lee , Cecilia Mascolo

Purpose: A reliable cancer prognosis model for clear cell renal cell carcinoma (ccRCC) can enhance personalized treatment. We developed a multi-modal ensemble model (MMEM) that integrates pretreatment clinical data, multi-omics data, and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Meixu Chen , Kai Wang , Payal Kapur , James Brugarolas , Raquibul Hannan , Jing Wang

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

CNN-LSTM based architectures have played an important role in image captioning, but limited by the training efficiency and expression ability, researchers began to explore the CNN-Transformer based models and achieved great success.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Yiyu Wang , Jungang Xu , Yingfei Sun

Standard decoding approaches for conditional text generation tasks typically search for an output hypothesis with high model probability, but this may not yield the best hypothesis according to human judgments of quality. Reranking to…

Computation and Language · Computer Science 2023-06-02 Prasann Singhal , Jiacheng Xu , Xi Ye , Greg Durrett

Large language models (LLMs) achieve remarkable generative performance, yet their output quality is dependent on the decoding strategy. While sampling-based methods (e.g., top-k, nucleus) and search-and-select based methods (e.g., beam…

Machine Learning · Computer Science 2026-05-12 Benjamin Patrick Evans , Sumitra Ganesh , Leo Ardon

Large unimodal foundation models for vision and language encode rich semantic structures, yet aligning them typically requires computationally intensive multimodal fine-tuning. Such approaches depend on large-scale parameter updates, are…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Abhishek Dalvi , Vasant Honavar

Training deep neural networks for 3D segmentation tasks can be challenging, often requiring efficient and effective strategies to improve model performance. In this study, we introduce a novel approach, DeCode, that utilizes label-derived…

Gene Regulatory Network (GRN) inference is essential for understanding complex cellular mechanisms, rendered tractable through single-cell transcriptomic data. With the emergence of single-cell Foundation Models (scFMs), enhanced…

Machine Learning · Computer Science 2026-05-12 Jiaxin Qi , Hang Li , Yan Cui , Yuhua Zheng , Jianqiang Huang

In this study, we introduce an innovative EEG signal reconstruction sub-module designed to enhance the performance of deep learning models on EEG eye-tracking tasks. This sub-module can integrate with all Encoder-Classifier-based deep…

Human-Computer Interaction · Computer Science 2024-08-13 Weigeng Li , Neng Zhou , Xiaodong Qu

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Medical foundation models have shown promise in controlled benchmarks, yet widespread deployment remains hindered by reliance on task-specific fine-tuning. Here, we introduce DermFM-Zero, a dermatology vision-language foundation model…

Recent studies have shown that code language models at scale demonstrate significant performance gains on downstream tasks, i.e., code generation. However, most of the existing works on code representation learning train models at a hundred…

Computation and Language · Computer Science 2024-02-06 Dejiao Zhang , Wasi Ahmad , Ming Tan , Hantian Ding , Ramesh Nallapati , Dan Roth , Xiaofei Ma , Bing Xiang