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We study the long-time tails of the survival probability $P(t)$ of an $A$ particle diffusing in $d$-dimensional media in the presence of a concentration $\rho$ of traps $B$ that move sub-diffusively, such that the mean square displacement…

Statistical Mechanics · Physics 2009-11-13 S. B. Yuste , G. Oshanin , K. Lindenberg , O. Benichou , J. Klafter

We consider a bivariate diffusion process and we study the first passage time of one component through a boundary. We prove that its probability density is the unique solution of a new integral equation and we propose a numerical algorithm…

Probability · Mathematics 2012-05-16 Elisa Benedetto , Laura Sacerdote , Cristina Zucca

Relatively general techniques for computing mean first-passage time (MFPT) of random walks on networks with a specific property are very useful, since a universal method for calculating MFPT on general graphs is not available because of…

Statistical Mechanics · Physics 2010-10-01 Yuan Lin , Bin Wu , Zhongzhi Zhang

A fluctuation theorem is examined for the first-passage time of a biomolecular machine (e.g., a motor protein or an enzyme) in a nonequilibrium steady-state. For such machines in which the driven, observable process is coupled to a hidden…

Biological Physics · Physics 2025-09-15 D. Evan Piephoff , Jianshu Cao

The mean first passage time (MFPT) for a Brownian particle to reach a small target in cellular microdomains is a key parameter for chemical activation. Although asymptotic estimations of the MFPT are available for various geometries, these…

Neurons and Cognition · Quantitative Biology 2015-03-19 Juergen Reingruber , David Holcman

Intracellular transport in living cells is often spatially inhomogeneous with an accelerated effective diffusion close to the cell membrane and a ballistic motion away from the centrosome due to active transport along actin filaments and…

Statistical Mechanics · Physics 2021-10-22 Matthieu Mangeat , Heiko Rieger

These notes are based on the lectures that I gave (virtually) at the Bruneck Summer School in 2021 on first-passage processes and some applications of the basic theory. I begin by defining what is a first-passage process and presenting the…

Statistical Mechanics · Physics 2025-01-14 S. Redner

We use a first-passage time approach to study the statistics of the trapping times induced by persistent motion of active particles colliding with flat boundaries. The angular first-passage time distribution and mean first-passage time is…

Statistical Mechanics · Physics 2022-08-02 Emily Qing Zang Moen , Kristian Stølevik Olsen , Jonas Rønning , Luiza Angheluta

We present an exact calculation of the mean first-passage time to a target on the surface of a 2D or 3D spherical domain, for a molecule alternating phases of surface diffusion on the domain boundary and phases of bulk diffusion. The…

Statistical Mechanics · Physics 2015-05-27 O. Bénichou , D. S. Grebenkov , P. E. Levitz , C. Loverdo , R. Voituriez

The effect of partial absorption on a diffusive particle which stochastically resets its position with a finite rate $r$ is considered. The particle is absorbed by a target at the origin with absorption `velocity' $a$; as the velocity $a$…

Statistical Mechanics · Physics 2015-06-12 Justin Whitehouse , Martin R. Evans , Satya N. Majumdar

We investigate the first-passage properties of nearest-neighbor hopping on a finite interval with disordered hopping rates. We develop an approach that relies on the backward equation, in conjunction with probability generating functions,…

Statistical Mechanics · Physics 2025-01-14 James Holehouse , S. Redner

Stochastic restart may drastically reduce the expected run time of a computer algorithm, expedite the completion of a complex search process, or increase the turnover rate of an enzymatic reaction. These diverse first-passage-time (FPT)…

Statistical Mechanics · Physics 2020-10-30 Shlomi Reuveni

We study the mean first-passage time (MFPT) for asymmetric continuous-time random walks in continuous-space characterised by waiting-times with finite mean and by jump-sizes with both finite mean and finite variance. In the asymptotic…

Statistical Mechanics · Physics 2023-01-11 M. Dahlenburg , G. Pagnini

In this paper, we develop a Monte Carlo based algorithm for estimating the FPT density of a time-homogeneous SDE through a time-dependent frontier. We consider Brownian bridges as well as localized Daniels curve approximations to obtain…

Probability · Mathematics 2013-07-02 Imene Allab , Francois Watier

Given a two-dimensional correlated diffusion process, we determine the joint density of the first passage times of the process to some constant boundaries. This quantity depends on the joint density of the first passage time of the first…

Probability · Mathematics 2017-01-26 Laura Sacerdote , Massimiliano Tamborrino , Cristina Zucca

We present exact results for the spectrum of the fractional Laplacian in a bounded domain and apply them to First Passage Time (FPT) Statistics of L\'evy flights. We specifically show that the average is insufficient to describe the…

Statistical Mechanics · Physics 2008-07-18 E. Katzav , M. Adda-Bedia

Single file systems are simplified models to study effectively one-dimensional physical systems. Here we compute analytically the complete first exit time statistics for an ideal overdamped single file with absorbing boundary conditions.…

Statistical Mechanics · Physics 2022-05-06 Alessio Lapolla

The statistics of the first-encounter time of diffusing particles changes drastically when they are placed under confinement. In the present work, we make use of Monte Carlo simulations to study the behavior of a two-particle system in two-…

Statistical Mechanics · Physics 2022-05-06 F. Le Vot , S. B. Yuste , E. Abad , D. S. Grebenkov

This paper considers the two-dimensional narrow escape problem in a domain which is composed of a relatively big head and several thin necks. The narrow escape problem is to compute the mean first passage time(MFPT) of a Brownian particle…

Mathematical Physics · Physics 2023-12-05 Xiaofei Li , Shengqi Lin

We have studied the dynamics of chloride and potassium ions in the interior of the OmpF porin under the influence of an external electric field. From the results of extensive all-atom molecular dynamics simulations of the system we computed…

Soft Condensed Matter · Physics 2015-05-20 Carles Calero , Jordi Faraudo , Marcel Aguilella-Arzo
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