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In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

A fundamental assumption of most machine learning algorithms is that the training and test data are drawn from the same underlying distribution. However, this assumption is violated in almost all practical applications: machine learning…

Machine Learning · Computer Science 2021-12-02 Marvin Zhang , Henrik Marklund , Nikita Dhawan , Abhishek Gupta , Sergey Levine , Chelsea Finn

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

Organ at risk (OAR) segmentation in computed tomography (CT) imagery is a difficult task for automated segmentation methods and can be crucial for downstream radiation treatment planning. U-net has become a de-facto standard for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Abdullah Nazib , Riad Hassan , Zahidul Islam , Clinton Fookes

Due to the domain discrepancy in visual domain adaptation, the performance of source model degrades when bumping into the high data density near decision boundary in target domain. A common solution is to minimize the Shannon Entropy to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-05 Shuhao Cui , Shuhui Wang , Junbao Zhuo , Liang Li , Qingming Huang , Qi Tian

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Yifei Yao , Hanrong Zhang

Ensembles of machine learning models yield improved system performance as well as robust and interpretable uncertainty estimates; however, their inference costs may often be prohibitively high. \emph{Ensemble Distribution Distillation} is…

Machine Learning · Computer Science 2021-05-17 Max Ryabinin , Andrey Malinin , Mark Gales

While domain adaptation methods address data shifts, most assume target populations align with at least one source population, neglecting mixtures that combine sources influenced by factors like demographics. Additional challenges in…

Methodology · Statistics 2025-05-02 Keyao Zhan , Xin Xiong , Zijian Guo , Tianxi Cai , Molei Liu

Recent works focus on synthesizing Chart Understanding (ChartU) training sets to inject advanced chart knowledge into Multimodal Large Language Models (MLLMs), where the sufficiency of the knowledge is typically verified by quantifying…

Machine Learning · Computer Science 2026-02-05 Jiapeng Liu , Liang Li , Bing Li , Peng Fu , Xiyan Gao , Chengyang Fang , Xiaoshuai Hao , Can Ma

In recent years, machine learning has witnessed extensive adoption across various sectors, yet its application in medical image-based disease detection and diagnosis remains challenging due to distribution shifts in real-world data. In…

Machine Learning · Computer Science 2024-02-13 Masoumeh Javanbakhat , Md Tasnimul Hasan , Cristoph Lippert

This paper focuses on the unsupervised domain adaptation of transferring the knowledge from the source domain to the target domain in the context of semantic segmentation. Existing approaches usually regard the pseudo label as the ground…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 Zhedong Zheng , Yi Yang

High-dimensional statistical inference deals with models in which the the number of parameters p is comparable to or larger than the sample size n. Since it is usually impossible to obtain consistent procedures unless $p/n\rightarrow0$, a…

Statistics Theory · Mathematics 2013-03-13 Sahand N. Negahban , Pradeep Ravikumar , Martin J. Wainwright , Bin Yu

Uncertainty estimation is essential to make neural networks trustworthy in real-world applications. Extensive research efforts have been made to quantify and reduce predictive uncertainty. However, most existing works are designed for…

Machine Learning · Computer Science 2022-10-07 Myong Chol Jung , He Zhao , Joanna Dipnall , Belinda Gabbe , Lan Du

In astronomy, neural networks are often trained on simulation data with the prospect of being used on telescope observations. Unfortunately, training a model on simulation data and then applying it to instrument data leads to a substantial…

Instrumentation and Methods for Astrophysics · Physics 2021-07-16 A. Ćiprijanović , D. Kafkes , K. Downey , S. Jenkins , G. N. Perdue , S. Madireddy , T. Johnston , G. F. Snyder , B. Nord

Purpose: Multiple sclerosis (MS) diagnosis requires accurate assessment of white matter hyperintensities (WMH) and ventricular changes on brain MRI. Current methods treat these structures independently, struggle to differentiate normal from…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Mahdi Bashiri Bawil , Mousa Shamsi , Abolhassan Shakeri Bavil

Geographic distribution shift arises when the distribution of locations on Earth in a training dataset is different from what is seen at inference time. Using standard empirical risk minimization (ERM) in this setting can lead to uneven…

Machine Learning · Computer Science 2026-02-10 Ruth Crasto , Esther Rolf

Entropy regularization is used to get improved optimization performance in reinforcement learning tasks. A common form of regularization is to maximize policy entropy to avoid premature convergence and lead to more stochastic policies for…

Machine Learning · Computer Science 2019-12-12 Riashat Islam , Zafarali Ahmed , Doina Precup

Decision trees partition the feature space using hard binary thresholds, assigning identical confidence to instances far from a decision boundary and to those directly on it. We introduce ternary decision trees, which augment each split…

Machine Learning · Computer Science 2026-05-22 William Smits