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Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Asbjørn Munk , Stefano Cerri , Vardan Nersesjan , Christian Hedeager Krag , Jakob Ambsdorf , Pablo Rocamora García , Julia Machnio , Peirong Liu , Suhyun Ahn , Nasrin Akbari , Yasmina Al Khalil , Kimberly Amador , Sina Amirrajab , Tal Arbel , Meritxell Bach Cuadra , Ujjwal Baid , Bhakti Baheti , Jaume Banus , Kamil Barbierik , Christoph Brune , Yansong Bu , Baptiste Callard , Yuhan Chen , Cornelius Crijnen , Corentin Dancette , Peter Drotar , Prasad Dutande , Nils D. Forkert , Saurabh Garg , Jakub Gazda , Matej Gazda , Benoît Gérin , Partha Ghosh , Weikang Gong , Pedro M. Gordaliza , Sam Hashemi , Tobias Heimann , Fucang Jia , Jiexin Jiang , Emily Kaczmarek , Chris Kang , Seung Kwan Kang , Mohammad Khazaei , Julien Khlaut , Petros Koutsouvelis , Jae Sung Lee , Yuchong Li , Mengye Lyu , Mingchen Ma , Anant Madabhushi , Klaus H. Maier-Hein , Pierre Manceron , Andrés Martínez Mora , Moona Mazher , Felix Meister , Nataliia Molchanova , Steven A. Niederer , Leonard Nürnberg , Jinah Park , Abdul Qayyum , Jonas Richiardi , Antoine Saporta , Branislav Setlak , Ning Shen , Justin Szeto , Constantin Ulrich , Puru Vaish , Vibujithan Vigneshwaran , Leroy Volmer , Zihao Wang , Siqi Wei , Anthony Winder , Jelmer M. Wolterink , Maxence Wynen , Chang Yang , Si Young Yie , Mostafa Mehdipour Ghazi , Akshay Pai , Espen Jimenez Solem , Sebastian Nørgaard Llambias , Mikael Boesen , Michael Eriksen Benros , Juan Eugenio Iglesias , Mads Nielsen

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique that records neural activations in the brain by capturing the blood oxygen level in different regions based on the task performed by a subject. Given fMRI data, the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Ashish Jaiswal , Ashwin Ramesh Babu , Mohammad Zaki Zadeh , Fillia Makedon , Glenn Wylie

The development of foundation models for brain MRI depends critically on the scale, diversity, and consistency of available data, yet systematic assessments of these factors remain scarce. In this study, we analyze 54 publicly accessible…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Minh Sao Khue Luu , Margaret V. Benedichuk , Ekaterina I. Roppert , Roman M. Kenzhin , Bair N. Tuchinov

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Haoyu Dong , Yuwen Chen , Hanxue Gu , Nicholas Konz , Yaqian Chen , Qihang Li , Maciej A. Mazurowski

Multi-sequence Magnetic Resonance Imaging (MRI) offers remarkable versatility, enabling the distinct visualization of different tissue types. Nevertheless, the inherent heterogeneity among MRI sequences poses significant challenges to the…

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

Machine Learning · Computer Science 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

Brain metastases are a common complication of systemic cancer, affecting over 20% of patients with primary malignancies. Longitudinal magnetic resonance imaging (MRI) is essential for diagnosing patients, tracking disease progression,…

Vision science, particularly machine vision, has been revolutionized by introducing large-scale image datasets and statistical learning approaches. Yet, human neuroimaging studies of visual perception still rely on small numbers of images…

Neurons and Cognition · Quantitative Biology 2020-01-23 Nadine Chang , John A. Pyles , Abhinav Gupta , Michael J. Tarr , Elissa M. Aminoff

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest…

Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data. Here we show that a single self-supervised representation can…

Machine Learning · Computer Science 2026-05-27 Yizhou Wu , Shansong Wang , Yuheng Li , Mojtaba Safari , Mingzhe Hu , Chih-Wei Chang , Harini Veeraraghavan , Xiaofeng Yang

Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Developing Foundation Models for medical image analysis is essential to overcome the unique challenges of radiological tasks. The first challenges of this kind for 3D brain MRI, SSL3D and FOMO25, were held at MICCAI 2025. Our solution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Pedro M. Gordaliza , Jaume Banus , Benoît Gérin , Maxence Wynen , Nataliia Molchanova , Jonas Richiardi , Meritxell Bach Cuadra

The University of California San Francisco Brain Metastases Stereotactic Radiosurgery (UCSF-BMSR) dataset is a public, clinical, multimodal brain MRI dataset consisting of 560 brain MRIs from 412 patients with expert annotations of 5136…

The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

This study investigates the impact of self-supervised pretraining of 3D semantic segmentation models on a large-scale, domain-specific dataset. We introduce BRAINS-45K, a dataset of 44,756 brain MRI volumes from public sources, the largest…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Asbjørn Munk , Jakob Ambsdorf , Sebastian Llambias , Mads Nielsen

Magnetic resonance imaging (MRI) is a crucial medical imaging modality. However, long acquisition times remain a significant challenge, leading to increased costs, and reduced patient comfort. Recent studies have shown the potential of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Amirmohammad Shamaei , Alexander Stebner , Salome , Bosshart , Johanna Ospel , Gouri Ginde , Mariana Bento , Roberto Souza

We present brat (brain report alignment transformer), a multi-view representation learning framework for brain magnetic resonance imaging (MRI) trained on MRIs paired with clinical reports. Brain MRIs present unique challenges due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Maxime Kayser , Maksim Gridnev , Wanting Wang , Max Bain , Aneesh Rangnekar , Avijit Chatterjee , Aleksandr Petrov , Harini Veeraraghavan , Nathaniel C. Swinburne

This retrospective-prospective study evaluated whether a deep learning-based MRI reconstruction algorithm can preserve diagnostic quality in brain MRI scans accelerated up to fourfold, using both public and prospective clinical data. The…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Jonathan I. Mandel , Shivaprakash Hiremath , Hedyeh Keshtgar , Timothy Scholl , Sadegh Raeisi
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