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Ensuring that machine learning (ML) models are safe, effective, and equitable across all patients is critical for clinical decision-making and for preventing the amplification of existing health disparities. In this work, we examine how…

Machine Learning · Computer Science 2025-05-28 Jianhui Gao , Benson Chou , Zachary R. McCaw , Hilary Thurston , Paul Varghese , Chuan Hong , Jessica Gronsbell

Machine learning (ML) has become a critical tool in public health, offering the potential to improve population health, diagnosis, treatment selection, and health system efficiency. However, biases in data and model design can result in…

Machine Learning · Computer Science 2023-04-12 Shaina Raza

The digitization of healthcare data coupled with advances in computational capabilities has propelled the adoption of machine learning (ML) in healthcare. However, these methods can perpetuate or even exacerbate existing disparities,…

Machine Learning · Computer Science 2024-02-02 Qizhang Feng , Mengnan Du , Na Zou , Xia Hu

Machine learning (ML) holds great promise for improving healthcare, but it is critical to ensure that its use will not propagate or amplify health disparities. An important step is to characterize the (un)fairness of ML models - their…

Machine Learning · Computer Science 2023-08-09 Alexander Brown , Nenad Tomasev , Jan Freyberg , Yuan Liu , Alan Karthikesalingam , Jessica Schrouff

Although deep learning (DL) models have shown great success in many medical image analysis tasks, deployment of the resulting models into real clinical contexts requires: (1) that they exhibit robustness and fairness across different…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Raghav Mehta , Changjian Shui , Tal Arbel

With the growing utilization of machine learning in healthcare, there is increasing potential to enhance healthcare outcomes. However, this also brings the risk of perpetuating biases in data and model design that can harm certain…

Machine Learning · Computer Science 2023-08-15 Shaina Raza , Parisa Osivand Pour , Syed Raza Bashir

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

Machine learning (ML) models often exhibit bias that can exacerbate inequities in biomedical applications. Fairness auditing, the process of evaluating a model's performance across subpopulations, is critical for identifying and mitigating…

Methodology · Statistics 2026-05-19 Jianhui Gao , Jessica Gronsbell

This paper studies the performance of large language models (LLMs), particularly regarding demographic fairness, in solving real-world healthcare tasks. We evaluate state-of-the-art LLMs with three prevalent learning frameworks across six…

Computation and Language · Computer Science 2024-12-10 Yue Zhou , Barbara Di Eugenio , Lu Cheng

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Deep learning algorithms have demonstrated remarkable efficacy in various medical image analysis (MedIA) applications. However, recent research highlights a performance disparity in these algorithms when applied to specific subgroups, such…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Zikang Xu , Jun Li , Qingsong Yao , Han Li , Mingyue Zhao , S. Kevin Zhou

Machine learning (ML) models may suffer from significant performance disparities between patient groups. Identifying such disparities by monitoring performance at a granular level is crucial for safely deploying ML to each patient.…

Machine Learning · Computer Science 2025-03-14 Alceu Bissoto , Trung-Dung Hoang , Tim Flühmann , Susu Sun , Christian F. Baumgartner , Lisa M. Koch

Unfair predictions of machine learning (ML) models impede their broad acceptance in real-world settings. Tackling this arduous challenge first necessitates defining what it means for an ML model to be fair. This has been addressed by the ML…

Machine Learning · Computer Science 2024-08-30 Selim Kuzucu , Jiaee Cheong , Hatice Gunes , Sinan Kalkan

Differences in data distributions between demographic groups, known as the problem of infra-marginality, complicate how people evaluate fairness in machine learning models. We present a user study with 85 participants in a hypothetical…

Human-Computer Interaction · Computer Science 2026-03-09 Schrasing Tong , Minseok Jung , Ilaria Liccardi , Lalana Kagal

Complex statistical machine learning models are increasingly being used or considered for use in high-stakes decision-making pipelines in domains such as financial services, health care, criminal justice and human services. These models are…

Applications · Statistics 2017-07-04 Alexandra Chouldechova , Max G'Sell

There are concerns about the fairness of clinical prediction models. 'Fair' models are defined as those for which their performance or predictions are not inappropriately influenced by protected attributes such as ethnicity, gender, or…

Applications · Statistics 2024-12-12 Jose Benitez-Aurioles , Alice Joules , Irene Brusini , Niels Peek , Matthew Sperrin

While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched…

Machine Learning · Computer Science 2022-05-19 Isabel Chien , Nina Deliu , Richard E. Turner , Adrian Weller , Sofia S. Villar , Niki Kilbertus

Fair machine learning (ML) methods help identify and mitigate the risk that algorithms encode or automate social injustices. Algorithmic approaches alone cannot resolve structural inequalities, but they can support socio-technical decision…

Machine Learning · Computer Science 2026-04-24 Michelle Seng Ah Lee , Kirtan Padh , David Watson , Niki Kilbertus , Jatinder Singh

In the current development and deployment of many artificial intelligence (AI) systems in healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent evaluation of AI models stratified across race…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Richard J. Chen , Tiffany Y. Chen , Jana Lipkova , Judy J. Wang , Drew F. K. Williamson , Ming Y. Lu , Sharifa Sahai , Faisal Mahmood

In recent years fairness in machine learning (ML) has emerged as a highly active area of research and development. Most define fairness in simple terms, where fairness means reducing gaps in performance or outcomes between demographic…

Artificial Intelligence · Computer Science 2023-03-14 Brent Mittelstadt , Sandra Wachter , Chris Russell
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