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Agentic systems offer a potential path to solve complex clinical tasks through collaboration among specialized agents, augmented by tool use and external knowledge bases. Nevertheless, for chest X-ray (CXR) interpretation, prevailing…

Multiagent Systems · Computer Science 2026-04-16 Kai Zhang , Corey D Barrett , Jangwon Kim , Lichao Sun , Tara Taghavi , Krishnaram Kenthapadi

Chest X-rays (CXRs) play an integral role in driving critical decisions in disease management and patient care. While recent innovations have led to specialized models for various CXR interpretation tasks, these solutions often operate in…

Machine Learning · Computer Science 2025-05-30 Adibvafa Fallahpour , Jun Ma , Alif Munim , Hongwei Lyu , Bo Wang

The widespread use of chest X-rays (CXRs), coupled with a shortage of radiologists, has driven growing interest in automated CXR analysis and AI-assisted reporting. While existing vision-language models (VLMs) show promise in specific tasks…

The escalating demand for medical image interpretation underscores the critical need for advanced artificial intelligence solutions to enhance the efficiency and accuracy of radiological diagnoses. This paper introduces CXR-PathFinder, a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Pimchanok Sukjai , Apiradee Boonmee

Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report…

Understanding how two radiology image sets differ is critical for generating clinical insights and for interpreting medical AI systems. We introduce RadDiff, a multimodal agentic system that performs radiologist-style comparative reasoning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Xiaoxian Shen , Yuhui Zhang , Sahithi Ankireddy , Xiaohan Wang , Maya Varma , Henry Guo , Curtis Langlotz , Serena Yeung-Levy

Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT). Yet, existing methods largely relegate clinicians to passive observers of final…

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Chest X-ray plays a central role in thoracic diagnosis, and its interpretation inherently requires multi-step, evidence-grounded reasoning. However, large vision-language models (LVLMs) often generate plausible responses that are not…

Artificial Intelligence · Computer Science 2026-03-25 Hyungyung Lee , Hangyul Yoon , Edward Choi

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

Deep learning based automated pathological diagnosis has markedly improved diagnostic efficiency and reduced variability between observers, yet its clinical adoption remains limited by opaque model decisions and a lack of traceable…

As artificial intelligence (AI) becomes increasingly central to healthcare, the demand for explainable and trustworthy models is paramount. Current report generation systems for chest X-rays (CXR) often lack mechanisms for validating…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier

Radiology visual question answering (RVQA) provides precise answers to questions about chest X-ray images, alleviating radiologists' workload. While recent methods based on multimodal large language models (MLLMs) and retrieval-augmented…

Artificial Intelligence · Computer Science 2025-08-06 Ziruo Yi , Jinyu Liu , Ting Xiao , Mark V. Albert

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

Deep learning models have achieved remarkable accuracy in chest X-ray diagnosis, yet their widespread clinical adoption remains limited by the black-box nature of their predictions. Clinicians require transparent, verifiable explanations to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yiming Tang , Wenjia Zhong , Rushi Shah , Dianbo Liu

Evaluating automatically generated radiology reports remains a fundamental challenge due to the lack of clinically grounded, interpretable, and fine-grained metrics. Existing methods either produce coarse overall scores or rely on opaque…

Computation and Language · Computer Science 2025-08-22 Yingshu Li , Yunyi Liu , Lingqiao Liu , Lei Wang , Luping Zhou

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Chest X-rays (CXRs) are among the most frequently performed imaging examinations worldwide, yet rising imaging volumes increase radiologist workload and the risk of diagnostic errors. Although artificial intelligence (AI) systems have shown…

Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation. However, these models often struggle to adapt to new diagnostic tasks…

Artificial Intelligence · Computer Science 2025-10-27 Jinhui Lou , Yan Yang , Zhou Yu , Zhenqi Fu , Weidong Han , Qingming Huang , Jun Yu

Chest X-ray (CXR) interpretation is a fundamental yet complex clinical task that increasingly relies on artificial intelligence for automation. However, traditional monolithic models often lack the nuanced reasoning required for trustworthy…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shawn Young , Lijian Xu
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