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In the present paper we present the potential of Explainable Artificial Intelligence methods for decision-support in medical image analysis scenarios. With three types of explainable methods applied to the same medical image data set our…

Artificial Intelligence · Computer Science 2021-05-20 Samanta Knapič , Avleen Malhi , Rohit Saluja , Kary Främling

As machine learning and algorithmic decision making systems are increasingly being leveraged in high-stakes human-in-the-loop settings, there is a pressing need to understand the rationale of their predictions. Researchers have responded to…

Machine Learning · Computer Science 2020-12-07 Jonathan Dinu , Jeffrey Bigham , J. Zico Kolter

As artificial intelligence and machine learning algorithms make further inroads into society, calls are increasing from multiple stakeholders for these algorithms to explain their outputs. At the same time, these stakeholders, whether they…

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

As large language models (LLMs) are increasingly deployed in sensitive domains such as healthcare, law, and education, the demand for transparent, interpretable, and accountable AI systems becomes more urgent. Explainable AI (XAI) acts as a…

Computers and Society · Computer Science 2025-05-28 Francisco Herrera

In recent years, Artificial Intelligence technology has excelled in various applications across all domains and fields. However, the various algorithms in neural networks make it difficult to understand the reasons behind decisions. For…

Artificial Intelligence · Computer Science 2025-05-13 Bowen Long , Enjie Liu , Renxi Qiu , Yanqing Duan

Explainable AI (XAI) aims to address the human need for safe and reliable AI systems. However, numerous surveys emphasize the absence of a sound mathematical formalization of key XAI notions -- remarkably including the term "explanation"…

Artificial Intelligence · Computer Science 2023-09-19 Pietro Barbiero , Stefano Fioravanti , Francesco Giannini , Alberto Tonda , Pietro Lio , Elena Di Lavore

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

While the capabilities and utility of AI systems have advanced, rigorous norms for evaluating these systems have lagged. Grand claims, such as models achieving general reasoning capabilities, are supported with model performance on narrow…

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

As AI regulations around the world intensify their focus on system safety, contestability has become a mandatory, yet ill-defined, safeguard. In XAI, "contestability" remains an empty promise: no formal definition exists, no algorithm…

Computers and Society · Computer Science 2025-06-03 Catarina Moreira , Anna Palatkina , Dacia Braca , Dylan M. Walsh , Peter J. Leihn , Fang Chen , Nina C. Hubig

Fairness of machine learning models in healthcare has drawn increasing attention from clinicians, researchers, and even at the highest level of government. On the other hand, the importance of developing and deploying interpretable or…

Machine Learning · Computer Science 2024-09-04 Mary M. Lucas , Xiaoyang Wang , Chia-Hsuan Chang , Christopher C. Yang , Jacqueline E. Braughton , Quyen M. Ngo

Recent legislative regulations have underlined the need for accountable and transparent artificial intelligence systems and have contributed to a growing interest in the Explainable Artificial Intelligence (XAI) field. Nonetheless, the lack…

Machine Learning · Computer Science 2025-10-14 Ilaria Vascotto , Alex Rodriguez , Alessandro Bonaita , Luca Bortolussi

Explainable Artificial Intelligence (XAI) methods help to understand the internal mechanism of machine learning models and how they reach a specific decision or made a specific action. The list of informative features is one of the most…

Artificial Intelligence · Computer Science 2024-06-18 Ahmed M Salih

If a product deviates from its desired properties in the injection moulding process, its root cause analysis can be aided by models that relate the input machine settings with the output quality characteristics. The machine learning models…

Machine Learning · Computer Science 2025-05-08 Muhammad Muaz , Sameed Sajid , Tobias Schulze , Chang Liu , Nils Klasen , Benny Drescher

Explainable AI (XAI) is widely viewed as a sine qua non for ever-expanding AI research. A better understanding of the needs of XAI users, as well as human-centered evaluations of explainable models are both a necessity and a challenge. In…

Artificial Intelligence · Computer Science 2024-10-17 Yao Rong , Tobias Leemann , Thai-trang Nguyen , Lisa Fiedler , Peizhu Qian , Vaibhav Unhelkar , Tina Seidel , Gjergji Kasneci , Enkelejda Kasneci

This paper establishes a theoretical foundation for understanding the fundamental limits of AI explainability through algorithmic information theory. We formalize explainability as the approximation of complex models by simpler ones,…

Artificial Intelligence · Computer Science 2025-11-04 Shrisha Rao

A core assumption of Explainable AI (XAI) is that explanations are useful to users -- that is, users will do something with the explanations. Prior work, however, does not clearly connect the information provided in explanations to user…

Human-Computer Interaction · Computer Science 2026-01-29 Gennie Mansi , Julia Kim , Mark Riedl

Applications of multilevel models usually result in binary classification within groups or hierarchies based on a set of input features. For transparent and ethical applications of such models, sound audit frameworks need to be developed.…

Computers and Society · Computer Science 2022-07-18 Debarati Bhaumik , Diptish Dey , Subhradeep Kayal

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

Machine Learning · Computer Science 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel
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