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Discriminative classifiers have become a foundational tool in deep learning for medical imaging, excelling at learning separable features of complex data distributions. However, these models often need careful design, augmentation, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Gian Mario Favero , Parham Saremi , Emily Kaczmarek , Brennan Nichyporuk , Tal Arbel

Diffusion models have had a profound impact on many application areas, including those where data are intrinsically infinite-dimensional, such as images or time series. The standard approach is first to discretize and then to apply…

Machine Learning · Statistics 2025-06-09 Jakiw Pidstrigach , Youssef Marzouk , Sebastian Reich , Sven Wang

Diffusion models have emerged as a formidable tool for training-free conditional generation.However, a key hurdle in inference-time guidance techniques is the need for compute-heavy backpropagation through the diffusion network for…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Nithin Gopalakrishnan Nair , Vishal M Patel

Classifier-guided diffusion models have emerged as a powerful approach for conditional image generation, but they suffer from overconfident predictions during early denoising steps, causing the guidance gradient to vanish. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Seyed Alireza Javid , Amirhossein Bagheri , Nuria González-Prelcic

Generative models have attracted significant interest due to their ability to handle uncertainty by learning the inherent data distributions. However, two prominent generative models, namely Generative Adversarial Networks (GANs) and…

Machine Learning · Computer Science 2023-04-25 Yu Wang , Zhiwei Liu , Liangwei Yang , Philip S. Yu

Diffusion probabilistic models have achieved enormous success in the field of image generation and manipulation. In this paper, we explore a novel paradigm of using the diffusion model and classifier guidance in the latent semantic space…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Changhao Shi , Haomiao Ni , Kai Li , Shaobo Han , Mingfu Liang , Martin Renqiang Min

This work introduces Variational Diffusion Distillation (VDD), a novel method that distills denoising diffusion policies into Mixtures of Experts (MoE) through variational inference. Diffusion Models are the current state-of-the-art in…

Machine Learning · Computer Science 2024-10-22 Hongyi Zhou , Denis Blessing , Ge Li , Onur Celik , Xiaogang Jia , Gerhard Neumann , Rudolf Lioutikov

Diffusion model-based approaches have shown promise in data-driven planning, but there are no safety guarantees, thus making it hard to be applied for safety-critical applications. To address these challenges, we propose a new method,…

Machine Learning · Computer Science 2023-06-02 Wei Xiao , Tsun-Hsuan Wang , Chuang Gan , Daniela Rus

Online black-box optimization (BBO) aims to optimize an objective function by iteratively querying a black-box oracle in a sample-efficient way. While prior studies focus on forward approaches such as Gaussian Processes (GPs) to learn a…

Machine Learning · Computer Science 2025-02-04 Dongxia Wu , Nikki Lijing Kuang , Ruijia Niu , Yi-An Ma , Rose Yu

Disordered metamaterials are promising for programming physical properties across diverse applications, yet their inverse design remains challenging due to the non-intuitive structure-property relationships and large design spaces. Recent…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Ziyuan Xie , Weipeng Xu , Dazhi Zhao , Wenchang Zhang , Daoyang Dong , Bingbing Xu , Ning Liu , Sheng Mao , Tianju Xue

Originating from the diffusion phenomenon in physics that describes particle movement, the diffusion generative models inherit the characteristics of stochastic random walk in the data space along the denoising trajectory. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Ruoyu Wang , Yongqi Yang , Zhihao Qian , Ye Zhu , Yu Wu

Recent advances in diffusion models have opened new avenues for research into embodied AI agents and robotics. Despite significant achievements in complex robotic locomotion and skills, mobile manipulation-a capability that requires the…

Robotics · Computer Science 2025-04-03 Sixu Yan , Zeyu Zhang , Muzhi Han , Zaijin Wang , Qi Xie , Zhitian Li , Zhehan Li , Hangxin Liu , Xinggang Wang , Song-Chun Zhu

Guided or controlled data generation with diffusion models\blfootnote{Partial preliminary results of this work appeared in International Conference on Machine Learning 2025 \citep{li2025provable}.} has become a cornerstone of modern…

Machine Learning · Statistics 2025-12-05 Yuchen Jiao , Yuxin Chen , Gen Li

We introduce Spectral Guidance, a framework for controlling diffusion models by leveraging the intrinsic geometry of the generative process. As data is progressively corrupted by noise, only a small number of features remain informative for…

Machine Learning · Computer Science 2026-05-29 Gabriel Moreira , Manuel Marques , João Paulo Costeira , Chenyan Xiong

Pathomics is a recent approach that offers rich quantitative features beyond what black-box deep learning can provide, supporting more reproducible and explainable biomarkers in digital pathology. However, many derived features (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Yuechen Yang , Junlin Guo , Ruining Deng , Junchao Zhu , Zhengyi Lu , Chongyu Qu , Yanfan Zhu , Xingyi Guo , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

The design of aerodynamic shapes, such as airfoils, has traditionally required significant computational resources and relied on predefined design parameters, which limit the potential for novel shape synthesis. In this work, we introduce a…

Machine Learning · Computer Science 2024-12-19 Reid Graves , Amir Barati Farimani

Guided diffusion-model generation is a promising direction for customizing the generation process of a pre-trained diffusion model to address specific downstream tasks. Existing guided diffusion models either rely on training the guidance…

Machine Learning · Computer Science 2025-04-01 Kim Yong Tan , Yueming Lyu , Ivor Tsang , Yew-Soon Ong

Diffusion models have emerged as powerful generative models for graph generation, yet their use for conditional graph generation remains a fundamental challenge. In particular, guiding diffusion models on graphs under arbitrary reward…

Machine Learning · Computer Science 2025-05-27 Victor M. Tenorio , Nicolas Zilberstein , Santiago Segarra , Antonio G. Marques

Diffusion models are a class of probabilistic generative models that have been widely used as a prior for image processing tasks like text conditional generation and inpainting. We demonstrate that these models can be adapted to make…

Machine Learning · Computer Science 2023-06-14 Marc Finzi , Anudhyan Boral , Andrew Gordon Wilson , Fei Sha , Leonardo Zepeda-Núñez

This paper introduces a simple formulation for topology optimization problems ensuring manufacturability by machining. The method distinguishes itself from existing methods by using the advection-diffusion equation with Robin boundary…

Computational Engineering, Finance, and Science · Computer Science 2022-02-16 Lukas Christian Høghøj , Erik Albert Träff