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Learning causal graphs from multivariate time series is a ubiquitous challenge in all application domains dealing with time-dependent systems, such as in Earth sciences, biology, or engineering, to name a few. Recent developments for this…

Methodology · Statistics 2024-07-02 Kevin Debeire , Jakob Runge , Andreas Gerhardus , Veronika Eyring

Understanding the complex relationships of biomarkers in diabetes is pivotal for advancing treatment strategies, a pressing need in diabetes research. This study applies Bayesian network structure learning to analyze the Shanghai Type 1 and…

Quantitative Methods · Quantitative Biology 2024-06-26 Yuyang Sun , Jingyu Lei , Panagiotis Kosmas

State-of-the-art techniques for detecting, or predicting, neurological disorders (1) focus on predicting each disorder individually, and are (2) computationally expensive, leading to a delay that can potentially render the prediction…

Signal Processing · Electrical Eng. & Systems 2020-12-29 Bharath Srinivas Prabakaran , Alberto García Jiménez , Germán Moltó Martínez , Muhammad Shafique

The accurate forecasting of infectious epidemic diseases is the key to effective control of the epidemic situation in a region. Most existing methods ignore potential dynamic dependencies between regions or the importance of temporal…

Machine Learning · Computer Science 2022-08-25 Feng Xie , Zhong Zhang , Xuechen Zhao , Bin Zhou , Yusong Tan

Significant advancements in type 1 diabetes treatment have been made in the development of state-of-the-art Artificial Pancreas Systems (APS). However, lapses currently exist in the timely treatment of unsafe blood glucose (BG) levels,…

Machine Learning · Computer Science 2023-03-20 Chloe Smith , Maxfield Kouzel , Xugui Zhou , Homa Alemzadeh

The rising rates of diabetes necessitate innovative methods for its management. Continuous glucose monitors (CGM) are small medical devices that measure blood glucose levels at regular intervals providing insights into daily patterns of…

Quantitative Methods · Quantitative Biology 2024-10-10 Renat Sergazinov , Elizabeth Chun , Valeriya Rogovchenko , Nathaniel Fernandes , Nicholas Kasman , Irina Gaynanova

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Predicting enzyme-substrate interactions has long been a fundamental problem in biochemistry and metabolic engineering. While existing methods could leverage databases of expert-curated enzyme-substrate pairs for models to learn from known…

Artificial Intelligence · Computer Science 2026-01-12 Tengwei Song , Long Yin , Zhen Han , Zhiqiang Xu

Machine learning has been successfully used in critical domains, such as medicine. However, extracting meaningful insights from biomedical data is often constrained by the lack of their available disease labels. In this research, we…

Quantitative Methods · Quantitative Biology 2025-04-02 Hido Pinto , Eran Segal

Heart disease is one of the most common diseases causing morbidity and mortality. Electrocardiogram (ECG) has been widely used for diagnosing heart diseases for its simplicity and non-invasive property. Automatic ECG analyzing technologies…

Machine Learning · Computer Science 2019-08-28 Yang Liu , Runnan He , Kuanquan Wang , Qince Li , Qiang Sun , Na Zhao , Henggui Zhang

Over 30 million Americans are affected by Type II diabetes (T2D), a treatable condition with significant health risks. This study aims to develop and validate predictive models using machine learning (ML) techniques to estimate emergency…

Quantitative Methods · Quantitative Biology 2024-12-13 Javad M Alizadeh , Jay S Patel , Gabriel Tajeu , Yuzhou Chen , Ilene L Hollin , Mukesh K Patel , Junchao Fei , Huanmei Wu

The increasing number of diabetic patients is a serious issue in society today, which has significant negative impacts on people's health and the country's financial expenditures. Because diabetes may develop into potential serious…

Artificial Intelligence · Computer Science 2024-04-18 Ziyi Zhou , Ming Cheng , Yanjun Cui , Xingjian Diao , Zhaorui Ma

With advanced data analytical techniques, efforts for more accurate decision support systems for disease prediction are on rise. Surveys by World Health Organization (WHO) indicate a great increase in number of diabetic patients and related…

Machine Learning · Computer Science 2017-06-27 Maham Jahangir , Hammad Afzal , Mehreen Ahmed , Khawar Khurshid , Raheel Nawaz

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

Machine Learning · Computer Science 2026-05-04 Alireza Namazi , Heman Shakeri

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

In the UK, approximately 400,000 people with type 1 diabetes (T1D) rely on insulin delivery due to insufficient pancreatic insulin production. Managing blood glucose (BG) levels is crucial, with continuous glucose monitoring (CGM) playing a…

Machine Learning · Computer Science 2023-12-21 Chengzhe Piao , Ken Li

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

learning algorithms. In this paper, we review the classification algorithms used in the health care system (chronic diseases) and present the neural network-based Ensemble learning method. We briefly describe the commonly used algorithms…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam , Mehdi Ghazanfari

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Biological signals, such as electroencephalograms (EEGs) and electrocardiograms (ECGs), play a pivotal role in numerous clinical practices, such as diagnosing brain and cardiac arrhythmic diseases. Existing methods for biosignal…

Machine Learning · Computer Science 2025-03-26 Jian Qian , Teck Lun Goh , Bingyu Xie , Chengyao Zhu , Biao Wan , Yawen Guan , Rachel Ding Chen , Patrick Yin Chiang