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Diabetes Mellitus, one of the leading causes of death worldwide, has no cure to date and can lead to severe health complications, such as retinopathy, limb amputation, cardiovascular diseases, and neuronal disease, if left untreated.…
Complex survey designs are commonly employed in many medical cohorts. In such scenarios, developing case-specific predictive risk score models that reflect the unique characteristics of the study design is essential for minimizing selective…
The integration of multimodal Electronic Health Records (EHR) data has significantly advanced clinical predictive capabilities. Existing models, which utilize clinical notes and multivariate time-series EHR data, often fall short of…
Artificial intelligence (AI) algorithms are a critical part of state-of-the-art digital health technology for diabetes management. Yet, access to large high-quality datasets is creating barriers that impede development of robust AI…
In the big data era, integrating diverse data modalities poses significant challenges, particularly in complex fields like healthcare. This paper introduces a new process model for multimodal Data Fusion for Data Mining, integrating…
Diabetes has affected over 246 million people worldwide with a majority of them being women. According to the WHO report, by 2025 this number is expected to rise to over 380 million. The disease has been named the fifth deadliest disease in…
Background: Predictive modeling is a key component of solutions to many healthcare problems. Among all predictive modeling approaches, machine learning methods often achieve the highest prediction accuracy, but suffer from a long-standing…
Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…
Type 1 diabetes is a serious disease in which individuals are unable to regulate their blood glucose levels, leading to various medical complications. Artificial pancreas (AP) systems have been developed as a solution for type 1 diabetic…
In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…
Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…
Diabetes is a chronic metabolic disorder characterized by persistently high blood glucose levels (BGLs), leading to severe complications such as cardiovascular disease, neuropathy, and retinopathy. Predicting BGLs enables patients to…
Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…
Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be…
Diabetes is one of the chronic diseases, which is increasing from year to year. The problems begin when diabetes is not detected at an early phase and diagnosed properly at the appropriate time. Different machine learning techniques, as…
Background and objective: Hybrid automated insulin delivery (hAID) systems represent the most advanced therapy for type 1 diabetes (T1D). Current systems rely on linear or linearized models of glucose homeostasis, which may compromise…
People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…
In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…
Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…
Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…