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Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

Modern deep learning methods have achieved impressive results across tasks from disease classification, estimating continuous biomarkers, to generating realistic medical images. Most of these approaches are trained to model conditional…

State-of-the-art systems neuroscience experiments yield large-scale multimodal data, and these data sets require new tools for analysis. Inspired by the success of large pretrained models in vision and language domains, we reframe the…

Neurons and Cognition · Quantitative Biology 2024-03-19 Antonis Antoniades , Yiyi Yu , Joseph Canzano , William Wang , Spencer LaVere Smith

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

In this study, we present a multimodal framework for predicting neuro-facial disorders by capturing both vocal and facial cues. We hypothesize that explicitly disentangling shared and modality-specific representations within multimodal…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-13 Mohd Mujtaba Akhtar , Girish , Muskaan Singh

Multi-center neuroimaging studies face technical variability due to batch differences across sites, which potentially hinders data aggregation and impacts study reliability.Recent efforts in neuroimaging harmonization have aimed to minimize…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Haoyu Lan , Bino A. Varghese , Nasim Sheikh-Bahaei , Farshid Sepehrband , Arthur W Toga , Jeiran Choupan

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Junren Pan , Shuqiang Wang

Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

Machine Learning · Computer Science 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Image-based personalized medicine has the potential to transform healthcare, particularly for diseases that exhibit heterogeneous progression such as Multiple Sclerosis (MS). In this work, we introduce the first treatment-aware…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Gian Mario Favero , Ge Ya Luo , Nima Fathi , Justin Szeto , Douglas L. Arnold , Brennan Nichyporuk , Chris Pal , Tal Arbel

Image segmentation, real-value prediction, and cross-modal translation are critical challenges in medical imaging. In this study, we propose a versatile multi-task neural network framework, based on an enhanced Transformer U-Net…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Zhuoyao Xin , Christopher Wu , Dong Liu , Chunming Gu , Jia Guo , Jun Hua

While deep learning methods have shown great success in medical image analysis, they require a number of medical images to train. Due to data privacy concerns and unavailability of medical annotators, it is oftentimes very difficult to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Yue Yang , Pengtao Xie

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Tracking microsctructural changes in the developing brain relies on accurate inter-subject image registration. However, most methods rely on either structural or diffusion data to learn the spatial correspondences between two or more…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Irina Grigorescu , Alena Uus , Daan Christiaens , Lucilio Cordero-Grande , Jana Hutter , A. David Edwards , Joseph V. Hajnal , Marc Modat , Maria Deprez

Medical generative models, acknowledged for their high-quality sample generation ability, have accelerated the fast growth of medical applications. However, recent works concentrate on separate medical generation models for distinct medical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Chenlu Zhan , Yu Lin , Gaoang Wang , Hongwei Wang , Jian Wu

For the first time, we propose using a multiple instance learning based convolution-free transformer model, called Multiple Instance Neuroimage Transformer (MINiT), for the classification of T1weighted (T1w) MRIs. We first present several…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Ayush Singla , Qingyu Zhao , Daniel K. Do , Yuyin Zhou , Kilian M. Pohl , Ehsan Adeli

This paper presents the Large Vision Diffusion Transformer (LaVin-DiT), a scalable and unified foundation model designed to tackle over 20 computer vision tasks in a generative framework. Unlike existing large vision models directly adapted…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Zhaoqing Wang , Xiaobo Xia , Runnan Chen , Dongdong Yu , Changhu Wang , Mingming Gong , Tongliang Liu

Large datasets often contain multiple distinct feature sets, or views, that offer complementary information that can be exploited by multi-view learning methods to improve results. We investigate anatomical multi-view data, where each brain…

Quantitative Methods · Quantitative Biology 2024-01-17 Yuxiang Wei , Yuqian Chen , Tengfei Xue , Leo Zekelman , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O' Donnell

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han