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Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…

Other Quantitative Biology · Quantitative Biology 2025-01-17 Kangli Dong , Siya Chen , Ying Dan , Lu Zhang , Xinyi Li , Wei Liang , Yue Zhao , Yu Sun

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

Neurons and Cognition · Quantitative Biology 2014-10-07 Andrew T. Sornborger , Louis Tao

Communication of signals among nodes in a complex network poses fundamental problems of efficiency and cost. Routing of messages along shortest paths requires global information about the topology, while spreading by diffusion, which…

Neurons and Cognition · Quantitative Biology 2019-06-19 Andrea Avena-Koenigsberger , Xiaoran Yan , Artemy Kolchinsky , Martijn van den Heuvel , Patric Hagmann , Olaf Sporns

The apparent stochasticity of in-vivo neural circuits has long been hypothesized to represent a signature of ongoing stochastic inference in the brain. More recently, a theoretical framework for neural sampling has been proposed, which…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Ilja Bytschok , Johannes Bill , Johannes Schemmel , Karlheinz Meier

Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…

Neural and Evolutionary Computing · Computer Science 2024-12-30 Ahmad El Ferdaoussi , Eric Plourde , Jean Rouat

Network of neurons in the brain apply - unlike processors in our current generation of computer hardware - an event-based processing strategy, where short pulses (spikes) are emitted sparsely by neurons to signal the occurrence of an event…

Neural and Evolutionary Computing · Computer Science 2014-12-19 Zeno Jonke , Stefan Habenschuss , Wolfgang Maass

Recent advancements in neurotechnology enable precise spatiotemporal patterns of microstimulations with single-cell resolution. The choice of perturbation sites must satisfy two key criteria: efficacy in evoking significant responses and…

Neurons and Cognition · Quantitative Biology 2025-06-02 Anandita De , Roozbeh Kiani , Luca Mazzucato

While spike timing has been shown to carry detailed stimulus information at the sensory periphery, its possible role in network computation is less clear. Most models of computation by neural networks are based on population firing rates.…

Neurons and Cognition · Quantitative Biology 2015-07-17 Michael A. Schwemmer , Adrienne L. Fairhall , Sophie Denéve , Eric T. Shea-Brown

Precise control of neural activity -- modulating target neurons deep in the brain while leaving nearby neurons unaffected -- is an outstanding challenge in neuroscience, generally approached using invasive techniques. This study…

Neurons and Cognition · Quantitative Biology 2025-06-17 Guy Gaziv , Sarah Goulding , Ani Ayvazian-Hancock , Yoon Bai , James J. DiCarlo

Estimating neuron location from extracellular recordings is essential for developing advanced brain-machine interfaces. Accurate neuron localization improves spike sorting, which involves detecting action potentials and assigning them to…

Neurons and Cognition · Quantitative Biology 2025-08-20 Hao Zhao , Xinhe Zhang , Arnau Marin-Llobet , Xinyi Lin , Jia Liu

The state space of a conventional Hopfield network typically exhibits many different attractors of which only a small subset satisfy constraints between neurons in a globally optimal fashion. It has recently been demonstrated that combining…

Adaptation and Self-Organizing Systems · Physics 2014-09-02 Alexander Woodward , Tom Froese , Takashi Ikegami

Knowledge about the collective dynamics of cortical spiking is very informative about the underlying coding principles. However, even most basic properties are not known with certainty, because their assessment is hampered by spatial…

Neurons and Cognition · Quantitative Biology 2019-03-13 Jens Wilting , Viola Priesemann

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

Neurons and Cognition · Quantitative Biology 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

We review different aspects of the simulation of spiking neural networks. We start by reviewing the different types of simulation strategies and algorithms that are currently implemented. We next review the precision of those simulation…

Simulation is a third pillar next to experiment and theory in the study of complex dynamic systems such as biological neural networks. Contemporary brain-scale networks correspond to directed graphs of a few million nodes, each with an…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-03 Jari Pronold , Jakob Jordan , Brian J. N. Wylie , Itaru Kitayama , Markus Diesmann , Susanne Kunkel

The highly variable dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference but stand in apparent contrast to the deterministic response of neurons measured in vitro.…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Simulation speed matters for neuroscientific research: this includes not only how quickly the simulated model time of a large-scale spiking neuronal network progresses, but also how long it takes to instantiate the network model in computer…

Large-scale neuromorphic architectures consist of computing tiles that communicate spikes using a shared interconnect. The communication patterns in such systems are inherently sparse, asynchronous, and localized due to the spiking nature…

Neural and Evolutionary Computing · Computer Science 2025-11-21 Phu Khanh Huynh , Francky Catthoor , Anup Das

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Optimization and Control · Mathematics 2024-09-23 Roman Chertovskih , Nikolay Pogodaev , Maxim Staritsyn , Joaquim Da Silva Sewane , Antonio Pedro Aguiar

Research showed that, the information transmitted in biological neurons is encoded in the instants of successive action potentials or their firing rate. In addition to that, in-vivo operation of the neuron makes measurement difficult and…

Neurons and Cognition · Quantitative Biology 2018-01-10 Ozgur Doruk , Kechen Zhang