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Quantum computation provides exponential speedup for solving certain mathematical problems against classical computers. Motivated by current rapid experimental progress on quantum computing devices, various models of quantum computation…

Quantum Physics · Physics 2018-03-28 Keisuke Fujii

Variational quantum algorithms (VQAs) are among the most promising algorithms to achieve quantum advantages in the NISQ era. One important challenge in implementing such algorithms is to construct an effective parameterized quantum circuit…

Quantum Physics · Physics 2024-07-26 Shikun Zhang , Zheng Qin , Yang Zhou , Rui Li , Chunxiao Du , Zhisong Xiao

Markov chain Monte Carlo algorithms have important applications in counting problems and in machine learning problems, settings that involve estimating quantities that are difficult to compute exactly. How much can quantum computers speed…

Quantum Physics · Physics 2020-02-10 Aram W. Harrow , Annie Y. Wei

In the quest to reboot computing, quantum annealing (QA) is an interesting candidate for a new capability. While it has not demonstrated an advantage over classical computing on a real-world application, many important regions of the QA…

We investigate a hybrid quantum-classical solution method to the mean-variance portfolio optimization problems. Starting from real financial data statistics and following the principles of the Modern Portfolio Theory, we generate…

Quantum Physics · Physics 2019-07-01 Davide Venturelli , Alexei Kondratyev

Quantum annealing (QA) is a method for solving combinatorial optimization problems. We can estimate the computational time for QA using the adiabatic condition. The adiabatic condition consists of two parts: an energy gap and a transition…

Quantum Physics · Physics 2024-08-28 Hiroshi Hayasaka , Takashi Imoto , Yuichiro Matsuzaki , Shiro Kawabata

Variational Quantum optimization algorithms, such as the Variational Quantum Eigensolver (VQE) or the Quantum Approximate Optimization Algorithm (QAOA), are among the most studied quantum algorithms. In our work, we evaluate and improve an…

Quantum Physics · Physics 2022-10-24 David Winderl , Nicola Franco , Jeanette Miriam Lorenz

The numerical solution of partial differential equations by discretization techniques is ubiquitous in computational physics. In this work we benchmark this approach in the quantum realm by solving the heat equation for a square plate…

We propose a modified MSA algorithm on quantum annealers with applications in areas of bioinformatics and genetic sequencing. To understand the human genome, researchers compare extensive sets of these genetic sequences -- or their protein…

Quantum Physics · Physics 2024-03-28 Melody Lee

Data scarcity remains a central challenge in materials discovery, where finding meaningful descriptors and tuning models for generalization is critical but inherently a discrete optimization problem prone to multiple local minima…

The application of quantum annealing to the optimization of continuous-variable functions is a relatively unexplored area of research. We test the performance of quantum annealing applied to a one-dimensional continuous-variable function…

Quantum Physics · Physics 2023-10-06 Shunta Arai , Hiroki Oshiyama , Hidetoshi Nishimori

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

With the increasing popularity of quantum computing and in particular quantum annealing, there has been growing research to evaluate the meta-heuristic for various problems in linear algebra: from linear least squares to matrix and tensor…

Quantum Physics · Physics 2024-10-28 Ajinkya Borle , Samuel J. Lomonaco

Quantum annealing targets low-energy solutions of Ising/QUBO problems, but reliable assessment requires more than best-energy comparisons. This dissertation develops a benchmarking framework for D-Wave quantum annealers that combines strong…

Quantum Physics · Physics 2026-05-01 Tomasz Śmierzchalski

We demonstrate that the performance of a quantum annealer on hard random Ising optimization problems can be substantially improved using quantum annealing correction (QAC). Our error correction strategy is tailored to the D-Wave Two device.…

Quantum Physics · Physics 2015-04-03 Kristen L. Pudenz , Tameem Albash , Daniel A. Lidar

Quantum annealing is a continuous-time heuristic quantum algorithm for solving or approximately solving classical optimization problems. The algorithm uses a schedule to interpolate between a driver Hamiltonian with an easy-to-prepare…

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

We present a hybrid classical-quantum computing paradigm where the quantum part strictly runs within the coherence time of a quantum annealer, a method we call variational coherent quantum annealing (VCQA). It involves optimizing the…

Quantum Physics · Physics 2023-10-04 N. Barraza , G. Alvarado Barrios , I. Montalban , E. Solano , F. Albarrán-Arriagada

We demonstrate experimentally that the bias-field digitized counterdiabatic quantum optimization (BF-DCQO) algorithm on IBM's 156-qubit devices can outperform simulated annealing (SA) and CPLEX in time-to-approximate solutions for specific…

Rydberg atom arrays have recently emerged as one of the most promising platforms for quantum simulation and quantum information processing. However, as is the case for other experimental platforms, the longer-term success of the Rydberg…

Quantum Physics · Physics 2022-12-07 Sina Zeytinoğlu , Sho Sugiura