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We describe a quantum algorithm that solves combinatorial optimization problems by quantum simulation of a classical simulated annealing process. Our algorithm exploits quantum walks and the quantum Zeno effect induced by evolution…

Quantum Physics · Physics 2009-02-02 R. D. Somma , S. Boixo , H. Barnum , E. Knill

We introduce quantum algorithms able to sample equilibrium water solvent molecules configurations within proteins thanks to analog quantum computing. To do so, we combine a quantum placement strategy to the 3D Reference Interaction Site…

Combinatorial optimization is widely regarded as a primary application for near-term quantum processors, although a definitive demonstration of the practical quantum advantage remains elusive. Recent studies have reported that both…

Quantum Physics · Physics 2026-05-21 Xian-Zhe Tao , Pavel Mosharev , Man-Hong Yung

Genetic algorithms are highly effective optimization techniques for many computationally challenging problems, including combinatorial optimization tasks like portfolio optimization. Quantum computing has also shown potential in addressing…

Emerging Technologies · Computer Science 2025-04-28 Mohammad Kashfi Haghighi , Matthieu Fortin-Deschênes , Christophe Pere , Mickaël Camus

Quantum annealing provides a promising route for the development of quantum optimization devices, but the usefulness of such devices will be limited in part by the range of implementable problems as dictated by hardware constraints. To…

Quantum Physics · Physics 2015-10-14 Walter Vinci , Tameem Albash , Gerardo Paz-Silva , Itay Hen , Daniel A. Lidar

Programmable quantum systems based on Rydberg atom arrays have recently been used for hardware-efficient tests of quantum optimization algorithms [Ebadi et al., Science, 376, 1209 (2022)] with hundreds of qubits. In particular, the maximum…

The observation of an unequivocal quantum speedup remains an elusive objective for quantum computing. The D-Wave quantum annealing processors have been at the forefront of experimental attempts to address this goal, given their relatively…

Quantum Physics · Physics 2018-08-08 Tameem Albash , Daniel A. Lidar

Quantum annealing (QA) and Quantum Alternating Operator Ansatz (QAOA) are both heuristic quantum algorithms intended for sampling optimal solutions of combinatorial optimization problems. In this article we implement a rigorous direct…

Quantum Physics · Physics 2023-08-31 Elijah Pelofske , Andreas Bärtschi , Stephan Eidenbenz

The quantum-classical hybrid variational quantum eigensolver (VQE) algorithm is arguably the most popular noisy intermediate-scale quantum (NISQ) era approach to quantum chemistry. We consider the underexplored quantum annealing eigensolver…

We propose and experimentally demonstrate sequential quantum computing (SQC), a paradigm that utilizes multiple homogeneous or heterogeneous quantum processors in hybrid classical-quantum workflows. In this manner, we are able to overcome…

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

Quantum Physics · Physics 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

We study algorithms inspired by quantum annealing that are suited for the NISQ era. First, we analyze approximate quantum annealing (AQA), which employs a discretized annealing ansatz in which the time step and the number of layers are…

Quantum Physics · Physics 2026-04-29 Rijul Sachdeva , Vrinda Mehta , Manpreet Singh Jattana , Kristel Michielsen , Fengping Jin

Node embedding is a key technique for representing graph nodes as vectors while preserving structural and relational properties, which enables machine learning tasks like feature extraction, clustering, and classification. While classical…

Quantum Physics · Physics 2025-03-11 Hristo N. Djidjev

With the rapid development of quantum computers, quantum algorithms have been studied extensively. However, quantum algorithms tackling statistical problems are still lacking. In this paper, we propose a novel non-oracular quantum adaptive…

Methodology · Statistics 2021-07-20 Wenxuan Zhong , Yuan Ke , Ye Wang , Yongkai Chen , Jinyang Chen , Ping Ma

Recent work has shown that quantum annealing for machine learning, referred to as QAML, can perform comparably to state-of-the-art machine learning methods with a specific application to Higgs boson classification. We propose QAML-Z, a…

Quantum Physics · Physics 2021-01-04 Alexander Zlokapa , Alex Mott , Joshua Job , Jean-Roch Vlimant , Daniel Lidar , Maria Spiropulu

Variational quantum algorithms exploit the features of superposition and entanglement to optimize a cost function efficiently by manipulating the quantum states. They are suitable for noisy intermediate-scale quantum (NISQ) computers that…

Quantum Physics · Physics 2023-08-29 Yunya Liu , Jiakun Liu , Jordan R. Raney , Pai Wang

Physically motivated classical heuristic optimization algorithms such as simulated annealing (SA) treat the objective function as an energy landscape, and allow walkers to escape local minima. It has been argued that quantum properties such…

Quantum Physics · Physics 2019-08-05 Aniruddha Bapat , Stephen Jordan

Quantum annealing is getting increasing attention in combinatorial optimization. The quantum processing unit by D-Wave is constructed to approximately solve Ising models on so-called Chimera graphs. Ising models are equivalent to quadratic…

Data Structures and Algorithms · Computer Science 2019-04-30 Michael Juenger , Elisabeth Lobe , Petra Mutzel , Gerhard Reinelt , Franz Rendl , Giovanni Rinaldi , Tobias Stollenwerk

The protocol of quantum annealing is applied to an optimization problem with a one-dimensional continuous degree of freedom, a variant of the problem proposed by Shinomoto and Kabashima. The energy landscape has a number of local minima,…

Quantum Physics · Physics 2022-06-23 Yang Wei Koh , Hidetoshi Nishimori

Predicting software defects early in the development process not only enhances the quality and reliability of the software but also decreases the cost of development. A wide range of machine learning techniques can be employed to create…

Software Engineering · Computer Science 2024-10-23 Ashis Kumar Mandal , Md Nadim , Chanchal K. Roy , Banani Roy , Kevin A. Schneider
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