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Protein evolution through amino acid mutations is a cornerstone of life sciences. Recent advances in protein language models have shown rich evolutionary patterns, offering unprecedented potential for in-silicon directed evolution. However,…

Artificial Intelligence · Computer Science 2026-01-08 Yaodong Yang , Yang Wang , Jinpeng Li , Pei Guo , Da Han , Guangyong Chen , Pheng-Ann Heng

2026 has brought an explosion of interest in LLM-guided evolution of agentic artifacts, with systems like GEPA and Autoresearch demonstrating that LLMs can iteratively improve prompts, code, and agent architectures across diverse domains.…

Artificial Intelligence · Computer Science 2026-04-07 Andrew Borthwick , Stephen Ash , Anthony Galczak

LLM-powered tool-calling agents fulfill user requests by interacting with environments, querying data, and invoking tools in a multi-turn process. Yet, most existing benchmarks evaluate these systems under static environment interfaces,…

Test-time Scaling (TTS) has been demonstrated to significantly enhance the reasoning capabilities of Large Language Models (LLMs) during the inference phase without altering model parameters. However, existing TTS methods are largely…

Computation and Language · Computer Science 2025-09-30 Guibin Zhang , Fanci Meng , Guancheng Wan , Zherui Li , Kun Wang , Zhenfei Yin , Lei Bai , Shuicheng Yan

Evolutionary computation (EC), as a powerful optimization algorithm, has been applied across various domains. However, as the complexity of problems increases, the limitations of EC have become more apparent. The advent of large language…

Neural and Evolutionary Computing · Computer Science 2024-05-24 Jinyu Cai , Jinglue Xu , Jialong Li , Takuto Ymauchi , Hitoshi Iba , Kenji Tei

Code translation transforms programs from one programming language (PL) to another. Several rule-based transpilers have been designed to automate code translation between different pairs of PLs. However, the rules can become obsolete as the…

Software Engineering · Computer Science 2025-06-23 Ali Reza Ibrahimzada , Kaiyao Ke , Mrigank Pawagi , Muhammad Salman Abid , Rangeet Pan , Saurabh Sinha , Reyhaneh Jabbarvand

Evolve pairs a small local language model with a persistent, teacher-compiled knowledge store -- refined through sleep consolidation and usage-driven refresh -- to deliver substantial accuracy gains over the model's parametric baseline…

Machine Learning · Computer Science 2026-04-28 Dikran Hovagimian

Recent progress in LLM-driven algorithm discovery, exemplified by DeepMind's AlphaEvolve, has produced new best-known solutions for a range of hard geometric and combinatorial problems. This raises a natural question: to what extent can…

Optimization and Control · Mathematics 2026-01-16 Timo Berthold , Dominik Kamp , Gioni Mexi , Sebastian Pokutta , Imre Pólik

Self-Refinement refers to a model's ability to revise its own responses to produce improved outputs. This capability can also serve as a fundamental mechanism for Self-Improvement, for example, by reconstructing datasets with refined…

Computation and Language · Computer Science 2025-10-28 Yongcheng Zeng , Xinyu Cui , Xuanfa Jin , Qirui Mi , Guoqing Liu , Zexu Sun , Mengyue Yang , Dong Li , Weiyu Ma , Ning Yang , Jian Zhao , Jianye Hao , Haifeng Zhang , Jun Wang

Extracting signals through alpha factor mining is a fundamental challenge in quantitative finance. Existing automated methods primarily follow two paradigms: Decoupled Factor Generation, which treats factor discovery as isolated events, and…

Artificial Intelligence · Computer Science 2026-02-13 Taian Guo , Haiyang Shen , Junyu Luo , Binqi Chen , Hongjun Ding , Jinsheng Huang , Luchen Liu , Yun Ma , Ming Zhang

With the end of Moore's Law, optimizing code for performance has become paramount for meeting ever-increasing compute demands, particularly in hyperscale data centers where even small efficiency gains translate to significant resource and…

Integrating Large Language Models (LLMs) and Evolutionary Computation (EC) represents a promising avenue for advancing artificial intelligence by combining powerful natural language understanding with optimization and search capabilities.…

Neural and Evolutionary Computing · Computer Science 2025-05-22 Dikshit Chauhan , Bapi Dutta , Indu Bala , Niki van Stein , Thomas Bäck , Anupam Yadav

In this paper we introduce ResearchCodeAgent, a novel multi-agent system leveraging large language models (LLMs) agents to automate the codification of research methodologies described in machine learning literature. The system bridges the…

Software Engineering · Computer Science 2025-05-06 Shubham Gandhi , Dhruv Shah , Manasi Patwardhan , Lovekesh Vig , Gautam Shroff

To evaluate the repository-level code generation capabilities of Large Language Models (LLMs) in complex real-world software development scenarios, many evaluation methods have been developed. These methods typically leverage contextual…

Software Engineering · Computer Science 2025-03-19 Dewu Zheng , Yanlin Wang , Ensheng Shi , Ruikai Zhang , Yuchi Ma , Hongyu Zhang , Zibin Zheng

Although real-coded differential evolution (DE) algorithms can perform well on continuous optimization problems (CoOPs), it is still a challenging task to design an efficient binary-coded DE algorithm. Inspired by the learning mechanism of…

Neural and Evolutionary Computing · Computer Science 2014-05-13 Yu Chen , Weicheng Xie , Xiufen Zou

Parallel accelerators, such as GPUs, are key enablers for large-scale Machine Learning (ML) applications. However, ML model developers often lack detailed knowledge of the underlying system architectures, while system programmers usually do…

Machine Learning · Computer Science 2023-10-17 Jhe-Yu Liou , Stephanie Forrest , Carole-Jean Wu

Designing evolutionary algorithms capable of uncovering highly evolvable representations is an open challenge; such evolvability is important because it accelerates evolution and enables fast adaptation to changing circumstances. This paper…

Neural and Evolutionary Computing · Computer Science 2019-07-16 Alexander Gajewski , Jeff Clune , Kenneth O. Stanley , Joel Lehman

Large Language Models (LLMs) have become pivotal tools for automating code generation in software development. However, these models face significant challenges in producing version-aware code for rapidly evolving languages like Rust, where…

Software Engineering · Computer Science 2025-03-24 Linxi Liang , Jing Gong , Mingwei Liu , Chong Wang , Guangsheng Ou , Yanlin Wang , Xin Peng , Zibin Zheng

Reinforcement learning with verifiable rewards (RLVR) has advanced the reasoning capabilities of large language models. However, existing methods rely solely on outcome rewards, without explicitly optimizing verification or leveraging…

Software Engineering · Computer Science 2025-10-22 Yiyang Jin , Kunzhao Xu , Hang Li , Xueting Han , Yanmin Zhou , Cheng Li , Jing Bai

The advent of Large Language Models (LLMs) has opened new frontiers in automated algorithm design, giving rise to numerous powerful methods. However, these approaches retain critical limitations: they require extensive evaluation of the…

Neural and Evolutionary Computing · Computer Science 2026-02-05 Haoran Yin , Shuaiqun Pan , Zhao Wei , Jian Cheng Wong , Yew-Soon Ong , Anna V. Kononova , Thomas Bäck , Niki van Stein