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The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fairness-Aware Interpretable Modeling (FAIM), to improve model…

Machine Learning · Computer Science 2024-03-11 Mingxuan Liu , Yilin Ning , Yuhe Ke , Yuqing Shang , Bibhas Chakraborty , Marcus Eng Hock Ong , Roger Vaughan , Nan Liu

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Objective: To pre-train fair and unbiased patient representations from Electronic Health Records (EHRs) using a novel weighted loss function that reduces bias and improves fairness in deep representation learning models. Methods: We defined…

Machine Learning · Computer Science 2023-06-07 Sonish Sivarajkumar , Yufei Huang , Yanshan Wang

Developing AI tools that preserve fairness is of critical importance, specifically in high-stakes applications such as those in healthcare. However, health AI models' overall prediction performance is often prioritized over the possible…

Machine Learning · Computer Science 2023-05-22 Raphael Poulain , Mirza Farhan Bin Tarek , Rahmatollah Beheshti

Biases in automated clinical decision-making using Electronic Healthcare Records (EHR) impose significant disparities in patient care and treatment outcomes. Conventional approaches have primarily focused on bias mitigation strategies…

Artificial Intelligence · Computer Science 2024-12-03 Resmi Ramachandranpillai , Kishore Sampath , Ayaazuddin Mohammad , Malihe Alikhani

Multimodal electronic health record (EHR) data can offer a holistic assessment of a patient's health status, supporting various predictive healthcare tasks. Recently, several studies have embraced the multitask learning approach in the…

Machine Learning · Computer Science 2024-06-19 Muhao Xu , Zhenfeng Zhu , Youru Li , Shuai Zheng , Yawei Zhao , Kunlun He , Yao Zhao

The widespread adoption of Electronic Health Record (EHR) systems in healthcare institutes has generated vast amounts of medical data, offering significant opportunities for improving healthcare services through deep learning techniques.…

Machine Learning · Computer Science 2024-01-23 Suhan Cui , Jiaqi Wang , Yuan Zhong , Han Liu , Ting Wang , Fenglong Ma

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Healthcare data are inherently multimodal, including electronic health records (EHR), medical images, and multi-omics data. Combining these multimodal data sources contributes to a better understanding of human health and provides optimal…

Machine Learning · Computer Science 2022-10-28 Farida Mohsen , Hazrat Ali , Nady El Hajj , Zubair Shah

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

Machine Learning · Computer Science 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu

Electronic Health Record (EHR) provides abundant information through various modalities. However, learning multi-modal EHR is currently facing two major challenges, namely, 1) data embedding and 2) cases with missing modality. A lack of…

Machine Learning · Computer Science 2023-05-05 Kwanhyung Lee , Soojeong Lee , Sangchul Hahn , Heejung Hyun , Edward Choi , Byungeun Ahn , Joohyung Lee

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient…

Artificial Intelligence · Computer Science 2022-01-19 Shuai Niu , Qing Yin , Yunya Song , Yike Guo , Xian Yang

Combining several embeddings typically improves performance in downstream tasks as different embeddings encode different information. It has been shown that even models using embeddings from transformers still benefit from the inclusion of…

Computation and Language · Computer Science 2021-11-01 Lukas Lange , Heike Adel , Jannik Strötgen , Dietrich Klakow

Ensuring equitable Artificial Intelligence (AI) in healthcare demands systems that make unbiased decisions across all demographic groups, bridging technical innovation with ethical principles. Foundation Models (FMs), trained on vast…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Dilermando Queiroz , Anderson Carlos , André Anjos , Lilian Berton

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

Computation and Language · Computer Science 2021-11-01 Bo Yang , Lijun Wu

Electronic health records (EHRs) are multimodal by nature, consisting of structured tabular features like lab tests and unstructured clinical notes. In real-life clinical practice, doctors use complementary multimodal EHR data sources to…

Computation and Language · Computer Science 2024-07-18 Thao Minh Nguyen Phan , Cong-Tinh Dao , Chenwei Wu , Jian-Zhe Wang , Shun Liu , Jun-En Ding , David Restrepo , Feng Liu , Fang-Ming Hung , Wen-Chih Peng

Multimodal emotion analysis performed better in emotion recognition depending on more comprehensive emotional clues and multimodal emotion dataset. In this paper, we developed a large multimodal emotion dataset, named "HED" dataset, to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zhongyu Fang , Aoyun He , Qihui Yu , Baopeng Gao , Weiping Ding , Tong Zhang , Lei Ma

Leveraging multimodal information from biosignals is vital for building a comprehensive representation of people's physical and mental states. However, multimodal biosignals often exhibit substantial distributional shifts between…

Machine Learning · Computer Science 2024-04-22 Ran Liu , Ellen L. Zippi , Hadi Pouransari , Chris Sandino , Jingping Nie , Hanlin Goh , Erdrin Azemi , Ali Moin

As machine learning models become increasingly integrated into healthcare, structural inequities and social biases embedded in clinical data can be perpetuated or even amplified by data-driven models. In survival analysis, censoring and…

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