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Multi-organ medical segmentation is a crucial component of medical image processing, essential for doctors to make accurate diagnoses and develop effective treatment plans. Despite significant progress in this field, current multi-organ…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Xinlei Yu , Changmiao Wang , Hui Jin , Ahmed Elazab , Gangyong Jia , Xiang Wan , Changqing Zou , Ruiquan Ge

The Segment Anything Model (SAM) has achieved a notable success in two-dimensional image segmentation in natural images. However, the substantial gap between medical and natural images hinders its direct application to medical image…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Quan Quan , Fenghe Tang , Zikang Xu , Heqin Zhu , S. Kevin Zhou

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Accurate vessel segmentation is critical for clinical applications such as disease diagnosis and surgical planning, yet remains challenging due to thin, branching structures and low texture contrast. While foundation models like the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Suzhong Fu , Rui Sun , Xuan Ding , Jingqi Dong , Yiming Yang , Yao Zhu , Min Chang Jordan Ren , Delin Deng , Angelica Aviles-Rivero , Shuguang Cui , Zhen Li

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have significantly impacted medical image segmentation, especially in retinal imaging, where precise segmentation is vital for diagnosis. Despite this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Shahrooz Faghihroohi , Kai Huang , Nassir Navab , M. Ali Nasseri

Accurate segmentation of brain tissues such as gray matter and white matter from magnetic resonance imaging is essential for studying brain anatomy, diagnosing neurological disorders, and monitoring disease progression. Traditional methods,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Chang Sun , Rui Shi , Tsukasa Koike , Tetsuro Sekine , Akio Morita , Tetsuya Sakai

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

Segmenting 3D objects into parts is a long-standing challenge in computer vision. To overcome taxonomy constraints and generalize to unseen 3D objects, recent works turn to open-world part segmentation. These approaches typically transfer…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Zhe Zhu , Le Wan , Rui Xu , Yiheng Zhang , Honghua Chen , Zhiyang Dou , Cheng Lin , Yuan Liu , Mingqiang Wei

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

The segmentation of metastatic bone disease (MBD) in whole-body MRI (WB-MRI) is a challenging problem. Due to varying appearances and anatomical locations of lesions, ambiguous boundaries, and severe class imbalance, obtaining reliable…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Joris Wuts , Jakub Ceranka , Nicolas Michoux , Frédéric Lecouvet , Jef Vandemeulebroucke

Statistical Shape Modeling (SSM) effectively analyzes anatomical variations within populations but is limited by the need for manual localization and segmentation, which relies on scarce medical expertise. Recent advances in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Janmesh Ukey , Tushar Kataria , Shireen Y. Elhabian

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Promptable segmentation, introduced by the Segment Anything Model (SAM), is a promising approach for medical imaging, as it enables clinicians to guide and refine model predictions interactively. However, SAM's architecture is designed for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Théo Danielou , Daniel Tordjman , Pierre Manceron , Corentin Dancette

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu