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Related papers: PRISM2: Unlocking Multi-Modal General Pathology AI…

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Surgical intelligence has the potential to improve the safety and consistency of surgical care, yet most existing surgical AI frameworks remain task-specific and struggle to generalize across procedures and institutions. Although multimodal…

Due to the increasing workload of pathologists, the need for automation to support diagnostic tasks and quantitative biomarker evaluation is becoming more and more apparent. Foundation models have the potential to improve generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Till Nicke , Jan Raphael Schaefer , Henning Hoefener , Friedrich Feuerhake , Dorit Merhof , Fabian Kiessling , Johannes Lotz

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Foundation vision-language models are currently transforming computer vision, and are on the rise in medical imaging fueled by their very promising generalization capabilities. However, the initial attempts to transfer this new paradigm to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Julio Silva-Rodríguez , Hadi Chakor , Riadh Kobbi , Jose Dolz , Ismail Ben Ayed

The growing demand for accurate and equitable AI models in digital dermatology faces a significant challenge: the lack of diverse, high-quality labeled data. In this work, we investigate the potential of domain-specific foundation models…

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly…

A vast majority of mass spectrometry data remains uncharacterized, leaving much of its biological and chemical information untapped. Recent advances in machine learning have begun to address this gap, particularly for tasks such as spectral…

In this paper, we consider the problem of visual representation learning for computational pathology, by exploiting large-scale image-text pairs gathered from public resources, along with the domain-specific knowledge in pathology.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Xiao Zhou , Xiaoman Zhang , Chaoyi Wu , Ya Zhang , Weidi Xie , Yanfeng Wang

Large unimodal foundation models for vision and language encode rich semantic structures, yet aligning them typically requires computationally intensive multimodal fine-tuning. Such approaches depend on large-scale parameter updates, are…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Abhishek Dalvi , Vasant Honavar

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

The rapid generation of whole-slide images (WSIs) in dermatopathology necessitates automated methods for efficient processing and accurate classification. This study evaluates the performance of two foundation models, UNI and Virchow2, as…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Riya Gupta , Yiwei Zong , Dennis H. Murphree

Lecture slide presentations, a sequence of pages that contain text and figures accompanied by speech, are constructed and presented carefully in order to optimally transfer knowledge to students. Previous studies in multimedia and…

Artificial Intelligence · Computer Science 2022-08-18 Dong Won Lee , Chaitanya Ahuja , Paul Pu Liang , Sanika Natu , Louis-Philippe Morency

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

We introduce PRISM (Predictive Reasoning in Sequential Medicine), a transformer-based architecture designed to model the sequential progression of clinical decision-making processes. Unlike traditional approaches that rely on isolated…

Computation and Language · Computer Science 2025-06-16 Lionel Levine , John Santerre , Alex S. Young , T. Barry Levine , Francis Campion , Majid Sarrafzadeh

Foundation models and vision-language pre-training have significantly advanced Vision-Language Models (VLMs), enabling multimodal processing of visual and linguistic data. However, their application in domain-specific agricultural tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Khang Nguyen Quoc , Phuong D. Dao , Luyl-Da Quach

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

As large language models (LLMs) evolve from conversational assistants into agents capable of handling complex tasks, they are increasingly deployed in high-risk domains. However, existing benchmarks largely rely on mixed queries and…

Computation and Language · Computer Science 2026-04-28 Yuhe Wu , Guangyu Wang , Yuran Chen , Jiatong Zhang , Yutong Zhang , Yujie Chen , Jiaming Shang , Guang Zhang , Zhuang Liu

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham