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Large language models (LLMs) have shown promise in various natural language processing tasks, including their application to proteomics data to classify protein fragments. In this study, we curated a limited mass spectrometry dataset with…

Quantitative Methods · Quantitative Biology 2025-02-28 Taylor A Phillips , Alejandro W. Huskey , Patrick T. Huskey , Seth L. Robia , Peter M. Kekenes-Huskey

Designing de novo proteins beyond those found in nature holds significant promise for advancements in both scientific and engineering applications. Current methodologies for protein design often rely on AI-based models, such as surrogate…

Soft Condensed Matter · Physics 2024-02-08 A. Ghafarollahi , M. J. Buehler

Fine-tuning large language models (LLMs) with low-rank adaptation (LoRA) is a cost-effective way to incorporate information from a specific dataset. However, when a problem requires incorporating information from multiple datasets - as in…

Machine Learning · Computer Science 2026-04-03 Liyi Zhang , Jake Snell , Thomas L. Griffiths

The proliferation of wearable technology enables the generation of vast amounts of sensor data, offering significant opportunities for advancements in health monitoring, activity recognition, and personalized medicine. However, the…

Human-Computer Interaction · Computer Science 2024-08-02 Emilio Ferrara

Existing tools to detect text generated by a large language model (LLM) have met with certain success, but their performance can drop when dealing with texts in new domains. To tackle this issue, we train a ranking classifier called…

Computation and Language · Computer Science 2024-10-21 You Zhou , Jie Wang

We investigate the adversarial robustness of LLMs in transfer learning scenarios. Through comprehensive experiments on multiple datasets (MBIB Hate Speech, MBIB Political Bias, MBIB Gender Bias) and various model architectures (BERT,…

Computation and Language · Computer Science 2025-06-10 Bohdan Turbal , Anastasiia Mazur , Jiaxu Zhao , Mykola Pechenizkiy

Med42-v2 introduces a suite of clinical large language models (LLMs) designed to address the limitations of generic models in healthcare settings. These models are built on Llama3 architecture and fine-tuned using specialized clinical data.…

Computation and Language · Computer Science 2024-08-13 Clément Christophe , Praveen K Kanithi , Tathagata Raha , Shadab Khan , Marco AF Pimentel

Unlocking the next generation of biotechnology and therapeutic innovation demands overcoming the inherent complexity and resource-intensity of conventional protein engineering methods. Recent GenAI-powered computational techniques often…

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

This paper conducts a comprehensive investigation into applying large language models, particularly on BioBERT, in healthcare. It begins with thoroughly examining previous natural language processing (NLP) approaches in healthcare, shedding…

Artificial Intelligence · Computer Science 2023-10-13 Shyni Sharaf , V. S. Anoop

In natural language processing, multilingual models like mBERT and XLM-RoBERTa promise broad coverage but often struggle with languages that share a script yet differ in orthographic norms and cultural context. This issue is especially…

Computation and Language · Computer Science 2025-07-28 Abdulhady Abas Abdullah , Amir H. Gandomi , Tarik A Rashid , Seyedali Mirjalili , Laith Abualigah , Milena Živković , Hadi Veisi

We train a suite of multimodal foundation models (MMFM) using the popular LLaVA framework with the recently released Gemma family of large language models (LLMs). Of particular interest is the 2B parameter Gemma model, which provides…

Computation and Language · Computer Science 2024-06-12 Musashi Hinck , Matthew L. Olson , David Cobbley , Shao-Yen Tseng , Vasudev Lal

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Social telehealth has revolutionized healthcare by enabling patients to share symptoms and receive medical consultations remotely. Users frequently post symptoms on social media and online health platforms, generating a vast repository of…

Computation and Language · Computer Science 2025-02-04 Malak Mohamed , Rokaia Emad , Ali Hamdi

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

This study introduces a systematic framework to compare the efficacy of Large Language Models (LLMs) for fine-tuning across various cheminformatics tasks. Employing a uniform training methodology, we assessed three well-known…

Machine Learning · Computer Science 2024-05-03 Lee Youngmin , Lang S. I. D. Andrew , Cai Duoduo , Wheat R. Stephen

In recent times, more and more people are posting about their mental states across various social media platforms. Leveraging this data, AI-based systems can be developed that help in assessing the mental health of individuals, such as…

Human-Computer Interaction · Computer Science 2024-12-20 Chayan Tank , Shaina Mehta , Sarthak Pol , Vinayak Katoch , Avinash Anand , Raj Jaiswal , Rajiv Ratn Shah

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim

With the rapid proliferation of large language models (LLMs) -- each optimized for different strengths, style, or latency/cost profile -- routing has become an essential technique to operationalize the use of different models. However,…

Computation and Language · Computer Science 2025-06-23 Co Tran , Salman Paracha , Adil Hafeez , Shuguang Chen