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Annotation of medical images has been a major bottleneck for the development of accurate and robust machine learning models. Annotation is costly and time-consuming and typically requires expert knowledge, especially in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Holger Roth , Ling Zhang , Dong Yang , Fausto Milletari , Ziyue Xu , Xiaosong Wang , Daguang Xu

Protein-DNA interaction is critical for life activities such as replication, transcription, and splicing. Identifying protein-DNA binding residues is essential for modeling their interaction and downstream studies. However, developing…

Biomolecules · Quantitative Biology 2023-06-29 Yufan Liu , Boxue Tian

We introduce an adaptive scattered data fitting scheme as extension of local least squares approximations to hierarchical spline spaces. To efficiently deal with non-trivial data configurations, the local solutions are described in terms of…

Numerical Analysis · Mathematics 2017-04-28 Cesare Bracco , Carlotta Giannelli , Alessandra Sestini

Deep learning's success has been attributed to the training of large, overparameterized models on massive amounts of data. As this trend continues, model training has become prohibitively costly, requiring access to powerful computing…

Machine Learning · Computer Science 2021-11-25 Ravi S Raju , Kyle Daruwalla , Mikko Lipasti

The idea of replacing hardware by software to compensate for scattered radiation in flat-panel X-ray imaging is well established in the literature. Recently, deep-learningbased image translation approaches, most notably the U-Net, have…

Standard deep neural networks (DNNs) are commonly trained in an end-to-end fashion for specific tasks such as object recognition, face identification, or character recognition, among many examples. This specificity often leads to…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Raphaël Achddou , J. Matias di Martino , Guillermo Sapiro

Pretrained Graph Neural Networks have been widely adopted for various molecular property prediction tasks. Despite their ability to encode structural and relational features of molecules, traditional fine-tuning of such pretrained GNNs on…

Machine Learning · Computer Science 2024-01-30 Vishal Dey , Xia Ning

Compressed sensing can increase resolution, and decrease electron dose and scan time of electron microscope point-scan systems with minimal information loss. Building on a history of successful deep learning applications in compressed…

Image and Video Processing · Electrical Eng. & Systems 2019-10-28 Jeffrey M. Ede

In recent years, deep neural networks have achieved great success in the field of computer vision. However, it is still a big challenge to deploy these deep models on resource-constrained embedded devices such as mobile robots, smart phones…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Yiming Hu , Siyang Sun , Jianquan Li , Xingang Wang , Qingyi Gu

Motivation: High-throughput experimental techniques have been producing more and more protein-protein interaction (PPI) data. PPI network alignment greatly benefits the understanding of evolutionary relationship among species, helps…

Data Structures and Algorithms · Computer Science 2016-04-13 Somaye Hashemifar , Qixing Huang , Jinbo XU

Protein inverse folding aims to design an amino acid sequence that will fold into a given backbone structure, serving as a central task in protein design. Two main paradigms have been widely explored. Template-based methods exploit…

Machine Learning · Computer Science 2026-03-17 Yiran Zhu , Changxi Chi , Hongxin Xiang , Wenjie Du , Xiaoqi Wang , Jun Xia

Automated prostate segmentation in MRI is highly demanded for computer-assisted diagnosis. Recently, a variety of deep learning methods have achieved remarkable progress in this task, usually relying on large amounts of training data. Due…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Quande Liu , Qi Dou , Lequan Yu , Pheng Ann Heng

Introducing explicit constraints on the structural predictions has been an effective way to improve the performance of semantic segmentation models. Existing methods are mainly based on insufficient hand-crafted rules that only partially…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Boxi Wu , Shuai Zhao , Wenqing Chu , Zheng Yang , Deng Cai

The problem of identifying splice sites consists of two sub-problems: finding their boundaries, and characterizing their sequence markers. Other splicing elements---including, enhancers and silencers---that occur in the intronic and exonic…

Quantitative Methods · Quantitative Biology 2012-06-27 Christine Lo , Boyko Kakaradov , Daniel Lokshtanov , Christina Boucher

miRNA and gene expression profiles have been proved useful for classifying cancer samples. Efficient classifiers have been recently sought and developed. A number of attempts to classify cancer samples using miRNA/gene expression profiles…

Computational Engineering, Finance, and Science · Computer Science 2014-01-21 Rania Ibrahim , Noha A. Yousri , Mohamed A. Ismail , Nagwa M. El-Makky

Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun

To empower precision agriculture through distributed machine learning (DML), split learning (SL) has emerged as a promising paradigm, partitioning deep neural networks (DNNs) between edge devices and servers to reduce computational burdens…

Machine Learning · Computer Science 2025-06-18 Vishesh Kumar Tanwar , Soumik Sarkar , Asheesh K. Singh , Sajal K. Das

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Imitation learning considerably simplifies policy synthesis compared to alternative approaches by exploiting access to expert demonstrations. For such imitation policies, errors away from the training samples are particularly critical. Even…

Machine Learning · Computer Science 2024-03-19 Kaustubh Sridhar , Souradeep Dutta , Dinesh Jayaraman , James Weimer , Insup Lee

In the field of medical image analysis, achieving high accuracy is not enough; ensuring well-calibrated predictions is also crucial. Confidence scores of a deep neural network play a pivotal role in explainability by providing insights into…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Abhishek Singh Sambyal , Usma Niyaz , Narayanan C. Krishnan , Deepti R. Bathula
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