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Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

We introduce CPPO, a Contrastive Perception Policy Optimization method for finetuning vision--language models (VLMs). Reliable perception is a core requirement for VLM-based agents that must reason and act in open-ended environments: faulty…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Ahmad Rezaei , Mohsen Gholami , Saeed Ranjbar Alvar , Kevin Cannons , Mohammad Asiful Hossain , Zhou Weimin , Yong Zhang , Mohammad Akbari

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

The VAPO framework has demonstrated significant empirical success in enhancing the efficiency and reliability of reinforcement learning for long chain-of-thought (CoT) reasoning tasks with large language models (LLMs). By systematically…

Machine Learning · Computer Science 2025-05-28 Jintian Shao , Yiming Cheng , Hongyi Huang , Beiwen Zhang , Zhiyu Wu , You Shan , Mingkai Zheng

Vision-Language Models (VLMs) have recently demonstrated incredible strides on diverse vision language tasks. We dig into vision-based deductive reasoning, a more sophisticated but less explored realm, and find previously unexposed…

Artificial Intelligence · Computer Science 2024-10-02 Yizhe Zhang , He Bai , Ruixiang Zhang , Jiatao Gu , Shuangfei Zhai , Josh Susskind , Navdeep Jaitly

Accurate diagnosis of ophthalmic diseases relies heavily on the interpretation of multimodal ophthalmic images, a process often time-consuming and expertise-dependent. Visual Question Answering (VQA) presents a potential interdisciplinary…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Xiaolan Chen , Ruoyu Chen , Pusheng Xu , Weiyi Zhang , Xianwen Shang , Mingguang He , Danli Shi

Reinforcement learning (RL) is increasingly used to post-train medical Vision-Language Models (VLMs), yet it remains unclear whether RL improves medical visual reasoning or mainly sharpens behaviors already induced by supervised fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ahmadreza Jeddi , Kimia Shaban , Negin Baghbanzadeh , Natasha Sharan , Abhishek Moturu , Elham Dolatabadi , Babak Taati

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

Computation and Language · Computer Science 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

Reasoning is a fundamental capability for solving complex multi-step problems, particularly in visual contexts where sequential step-wise understanding is essential. Existing approaches lack a comprehensive framework for evaluating visual…

Current vision-language models (VLMs) still exhibit inferior performance on knowledge-intensive tasks, primarily due to the challenge of accurately encoding all the associations between visual objects and scenes to their corresponding…

Computation and Language · Computer Science 2024-10-16 Jingyuan Qi , Zhiyang Xu , Rulin Shao , Yang Chen , Jin Di , Yu Cheng , Qifan Wang , Lifu Huang

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

Artificial Intelligence · Computer Science 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

As a cornerstone of patient care, clinical decision-making significantly influences patient outcomes and can be enhanced by large language models (LLMs). Although LLMs have demonstrated remarkable performance, their application to visual…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Ji Young Byun , Young-Jin Park , Navid Azizan , Rama Chellappa

A reliable driving assistant should provide consistent responses based on temporally grounded reasoning derived from observed information. In this work, we investigate whether Vision-Language Models (VLMs), when applied as driving…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Chun-Peng Chang , Chen-Yu Wang , Holger Caesar , Alain Pagani

Recent work shows that text-only reinforcement learning with verifiable rewards (RLVR) can match or outperform image-text RLVR on multimodal medical VQA benchmarks, suggesting current evaluation protocols may fail to measure causal visual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Anas Zafar , Leema Krishna Murali , Ashish Vashist

Effectively retrieving, reasoning and understanding visually rich information remains a challenge for RAG methods. Traditional text-based methods cannot handle visual-related information. On the other hand, current vision-based RAG…

Computation and Language · Computer Science 2025-06-04 Qiuchen Wang , Ruixue Ding , Yu Zeng , Zehui Chen , Lin Chen , Shihang Wang , Pengjun Xie , Fei Huang , Feng Zhao

Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent…

Machine Learning · Computer Science 2026-01-27 Peng Xia , Jinglu Wang , Yibo Peng , Kaide Zeng , Zihan Dong , Xian Wu , Xiangru Tang , Hongtu Zhu , Yun Li , Linjun Zhang , Shujie Liu , Yan Lu , Huaxiu Yao

Recent progress in medical vision-language models (VLMs) has achieved strong performance on image-level text-centric tasks such as report generation and visual question answering (VQA). However, achieving fine-grained visual grounding and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Yang Xing , Jiong Wu , Savas Ozdemir , Ying Zhang , Yang Yang , Wei Shao , Kuang Gong

In question-answering scenarios, humans can assess whether the available information is sufficient and seek additional information if necessary, rather than providing a forced answer. In contrast, Vision Language Models (VLMs) typically…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Li Liu , Diji Yang , Sijia Zhong , Kalyana Suma Sree Tholeti , Lei Ding , Yi Zhang , Leilani H. Gilpin

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Building robust vision systems for high-stakes domains such as remote sensing requires stronger visual reasoning than what single-pass inference typically provides; yet, retraining large models is often computationally expensive and data…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Chung-En Johnny Yu , Brian Jalaian , Nathaniel D. Bastian