Related papers: New tissue engineered scaffolds for rotator cuff t…
Many people suffering from skin disorders such as chronic wounds, non-healing ulcers, and diabetic ulcers need skin repair and regeneration. Aside from the diseases listed above, the industry needed a skin rejuvenation system and…
The identification and segmentation of moderate-severe traumatic brain injury (TBI) lesions pose a significant challenge in neuroimaging. This difficulty arises from the extreme heterogeneity of these lesions, which vary in size, number,…
Traumatic Brain Injury (TBI) poses a significant global public health challenge, contributing to high morbidity and mortality rates and placing a substantial economic burden on healthcare systems worldwide. The diagnosis of TBI relies on…
We consider a simple one-dimensional time-dependent model for bone regeneration in the presence of a bio-resorbable polymer scaffold. Within the framework of the model, we optimize the effective mechanical stiffness of the polymer scaffold…
Biodegradable elastic scaffolds have attracted more and more attention in the field of soft tissue repair and tissue engineering. These scaffolds made of porous bioelastomers support tissue ingrowth along with their own degradation. It is…
The technique presented here identifies tethered mould designs, optimised for growing cultured tissue with very highly-aligned cells. It is based on a microscopic biophysical model for polarised cellular hydrogels. There is an unmet need…
Surgical planning for complex tibial fractures can be challenging for surgeons, as the 3D structure of the later desirable bone alignment may be difficult to imagine. To assist in such planning, we address the challenge of predicting a…
Traumatic Brain Injury (TBI) is a common cause of death and disability. However, existing tools for TBI diagnosis are either subjective or require extensive clinical setup and expertise. The increasing affordability and reduction in size of…
Brain injuries resulting from mechanical trauma represent an ongoing global public health issue. Several $\textit{in vitro}$ and $\textit{in vivo}$ models for traumatic brain injury (TBI) continue to be developed for delineating the various…
Traumatic brain injury (TBI) is caused by a sudden trauma to the head that may result in hematomas and contusions and can lead to stroke or chronic disability. An accurate quantification of the lesion volumes and their locations is…
Development of additive manufacturing in last decade greatly improves tissue engineering. During the manufacturing of porous scaffold, simplified but functionally equivalent models are getting focused for practically reasons. Scaffolds can…
The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…
The control and task automation of robotic surgical system is very challenging, especially in soft tissue manipulation, due to the unpredictable deformations. Thus, an accurate simulator of soft tissues with the ability of interacting with…
We propose a simple model for scaffold aided bone regeneration. In this model, only macroscopic quantities, e.g., locally averaged osteoblast densities, are considered. This allows for use of this model in an optimization algorithm, whose…
Developing successful scaffolds requires clinicians to adopt a multidisciplinary approach in order to understand and stimulate the natural bone regeneration process. A variety of natural and synthetic biomaterials, including naturally…
Reconstruction of the mandible is one of the most common challenges facing maxillofacial surgeons. The mandible plays a major role in supporting the teeth inside the mouth. This work aims to develop a proposed methodology for improving…
The development of tissue-engineered cardiovascular implants can improve the lives of large segments of our society who suffer from cardiovascular diseases. Regenerative tissues are fabricated using a process called tissue maturation.…
Long-term bone healing/adaptation after a dental implant treatment starts with diffusion of mesenchymal stem cells to the fracture callus and their subsequent differentiation. The healing phase is followed by the bone-remodeling phase. In…
The trajectory of an individual's recovery after traumatic brain injury (TBI) is heterogeneous, with complete recovery in some cases but persistent disability in others. We hypothesized that changes in structural brain network abnormalities…
Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…