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Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations. Deep Learning recently has shown promising progress in many…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Mina Rezaei , Haojin Yang , Christoph Meinel

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

For the study of functional aspects of the brain network. This paper is a study on the hypergraph representation, based on the functional regions of the brain network. A new parameter that can measure how many multifunctioning regions each…

Neurons and Cognition · Quantitative Biology 2023-12-20 Anagha P , Selvakumar R

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Noninvasive medical neuroimaging has yielded many discoveries about the brain connectivity. Several substantial techniques mapping morphological, structural and functional brain connectivities were developed to create a comprehensive road…

Machine Learning · Computer Science 2022-09-30 Alaa Bessadok , Mohamed Ali Mahjoub , Islem Rekik

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

Brain functional network has become an increasingly used approach in understanding brain functions and diseases. Many network construction methods have been developed, whereas the majority of the studies still used static pairwise Pearson's…

Neurons and Cognition · Quantitative Biology 2020-03-13 Zhen Zhou , Xiaobo Chen , Yu Zhang , Lishan Qiao , Renping Yu , Gang Pan , Han Zhang , Dinggang Shen

Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Medical image segmentation is essential for clinical applications such as disease diagnosis, treatment planning, and disease development monitoring because it provides precise morphological and spatial information on anatomical structures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Moin Safdar , Shahzaib Iqbal , Mubeen Ghafoor , Tariq M. Khan , Imran Razzak , Thantrira Porntaveetus , Hamid Alinejad-Rokny

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

Human brain connectome studies aim at extracting and analyzing relevant features associated to pathologies of interest. Usually this consists in modeling the brain connectome as a graph and in using graph metrics as features. A fine brain…

Neurons and Cognition · Quantitative Biology 2020-05-04 Félix Renard , Christian Heinrich , Marine Bouthillon , Maleka Schenck , Francis Schneider , Stéphane Kremer , Sophie Achard

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

Comprehensive surgical planning require complex patient-specific anatomical models. For instance, functional muskuloskeletal simulations necessitate all relevant structures to be segmented, which could be performed in real-time using deep…

Image and Video Processing · Electrical Eng. & Systems 2019-05-20 Firat Ozdemir , Orcun Goksel

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy