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The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

We propose a deep neural network for supervised learning on neuroanatomical shapes. The network directly operates on raw point clouds without the need for mesh processing or the identification of point correspondences, as spatial…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Benjamin Gutierrez-Becker , Christian Wachinger

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Brain tumor segmentation is a critical task in medical image analysis, aiding in the diagnosis and treatment planning of brain tumor patients. The importance of automated and accurate brain tumor segmentation cannot be overstated. It…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Muhammad Ansab Butt , Absaar Ul Jabbar

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

Machine Learning · Statistics 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

Methodology · Statistics 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

Quantitative Methods · Quantitative Biology 2016-02-03 Sean L. Simpson , Paul J. Laurienti

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sarah Itani , Dorina Thanou

Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view…

Neurons and Cognition · Quantitative Biology 2017-01-05 John D. Medaglia , Danielle S. Bassett

Interpretable deep learning models have received widespread attention in the field of image recognition. Due to the unique multi-instance learning of medical images and the difficulty in identifying decision-making regions, many…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yitao Peng , Lianghua He , Die Hu , Yihang Liu , Longzhen Yang , Shaohua Shang

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

Machine Learning · Computer Science 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

Brain tumor classification is crucial for clinical analysis and an effective treatment plan to cure patients. Deep learning models help radiologists to accurately and efficiently analyze tumors without manual intervention. However, brain…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Mirza Mumtaz Zahoor , Saddam Hussain Khan

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

Automatic segmentation of fine-grained brain structures remains a challenging task. Current segmentation methods mainly utilize 2D and 3D deep neural networks. The 2D networks take image slices as input to produce coarse segmentation in…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Yuemeng Li , Hangfan Liu , Hongming Li , Yong Fan