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The seasonality of respiratory diseases (common cold, influenza, etc.) is a well-known phenomenon studied from ancient times. The development of predictive models is still not only an actual unsolved problem of mathematical epidemiology but…

Populations and Evolution · Quantitative Biology 2014-04-28 Eugene B. Postnikov , Dmitry V. Tatarenkov

Identifiability is a central issue in blind source separation (BSS), determining whether latent sources can be uniquely recovered from observed mixtures. Classical approaches address identifiability either by exploiting source…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Tomomi Ogawa , Hiroki Matsumoto

In this paper we present a model describing Susceptible-Infected-Susceptible (SIS) type epidemics spreading on a dynamic contact network with random link activation and deletion where link ac- tivation can be locally constrained. We use and…

Dynamical Systems · Mathematics 2015-05-30 Michael Taylor , Timothy J. Taylor , Istvan Z. Kiss

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

In this paper, we revisit the fault diagnosis problem of discrete-event systems (DES) under non-deterministic observations. Non-deterministic observation is a general observation model that includes the case of intermittent loss of…

Systems and Control · Electrical Eng. & Systems 2022-04-07 Weijie Dong , Shang Gao , Xiang Yin , Shaoyuan Li

Parameter identifiability is a structural property of an ODE model for recovering the values of parameters from the data (i.e., from the input and output variables). This property is a prerequisite for meaningful parameter identification in…

Systems and Control · Electrical Eng. & Systems 2021-06-07 Alexey Ovchinnikov , Anand Pillay , Gleb Pogudin , Thomas Scanlon

Hybrid systems are traditionally difficult to identify and analyze using classical dynamical systems theory. Moreover, recently developed model identification methodologies largely focus on identifying a single set of governing equations…

Dynamical Systems · Mathematics 2019-06-19 Niall M Mangan , Travis Askham , Steven L Brunton , J Nathan Kutz , Joshua L Proctor

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e. the number of…

Populations and Evolution · Quantitative Biology 2019-12-05 F. Di Lauro , J. -C. Croix , M. Dashti , L. Berthouze , I. Z. Kiss

Data-driven discovery of model equations is a powerful approach for understanding the behavior of dynamical systems in many scientific fields. In particular, the ability to learn mathematical models from data would benefit systems biology,…

Machine Learning · Computer Science 2025-11-04 G. Pillonetto , A. Giaretta , A. Aravkin , M. Bisiacco , T. Elston

In designed experiments and surveys, known laws or design feat ures provide checks on the most relevant aspects of a model and identify the target parameters. In contrast, in most observational studies in the health and social sciences, the…

Methodology · Statistics 2010-01-18 Sander Greenland

Ordinary differential equation models have become a standard tool for the mechanistic description of biochemical processes. If parameters are inferred from experimental data, such mechanistic models can provide accurate predictions about…

Quantitative Methods · Quantitative Biology 2018-10-12 Fabian Fröhlich , Carolin Loos , Jan Hasenauer

The primary goal of this research is to investigate the impact of delay on the dynamics of the Susceptible-Exposed-Infected-Recovered-Death and Susceptible (SEIRDS) model, to which we add a stochastic term to account for uncertainty in…

Populations and Evolution · Quantitative Biology 2022-08-17 Mohamed Ben Alaya , Walid Ben Aribi , Slimane Ben Miled

We investigate an epidemic model based on Bailey's continuous differential system. In the continuous time domain, we extend the classical model to time-dependent coefficients and present an alternative solution method to Gleissner's…

Classical Analysis and ODEs · Mathematics 2019-01-01 Martin Bohner , Sabrina Streipert , Delfim F. M. Torres

Understanding infectious disease spread remains a critical public health challenge, particularly given the interplay between household dynamics and community transmission patterns. Traditional epidemiological models often oversimplify these…

Populations and Evolution · Quantitative Biology 2026-01-21 Houda Yaqine , Christiane Fuchs

We investigate the application of a framework for sparse model identification of differential equations from timeseries data in the context of compartmental models in epidemiology. Such frameworks often seek a sparse representation from a…

Optimization and Control · Mathematics 2025-10-23 Manuchehr Aminian , Kristin M. Kurianski

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

Methodology · Statistics 2023-06-26 Chih-Li Sung , Ying Hung

Global pandemics, such as the recent COVID-19 crisis, highlight the need for stochastic epidemic models that can capture the randomness inherent in the spread of disease. Such models must be accompanied by methods for estimating parameters…

Quantitative Methods · Quantitative Biology 2026-04-13 Vincent Wieland , Nils Wassmuth , Lorenzo Contento , Martin Kühn , Jan Hasenauer

In this paper, we investigate the problem of mitigating epidemics by applying an event-triggered control strategy. We consider a susceptible-infected-removed-susceptible (SIRS) model, which builds upon the foundational SIR model by…

Systems and Control · Electrical Eng. & Systems 2023-10-17 Lichen Ding , Kazumune Hashimoto , Shigemasa Takai

We study the Suscectible-Infected-Recovered-Susceptible (SIRS) epidemic model on deterministic networks. For connected but otherwise general interaction patterns and heterogeneous recovery and loss-of-immunity rates, we identify a…

Systems and Control · Electrical Eng. & Systems 2026-04-24 Giulia Gatti , Giacomo Como

Petri Nets are an increasingly used modeling framework for the spread of disease across populations or within an individual. For example, the Susceptible-Infectious-Recovered (SIR) compartment model is foundational for population…

Other Quantitative Biology · Quantitative Biology 2025-07-02 Trevor Reckell , Bright Kwaku Manu , Beckett Sterner , Petar Jevtić , Reggie Davidrajuh
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