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We present a simple, modular graph-based convolutional neural network that takes structural information from protein-ligand complexes as input to generate models for activity and binding mode prediction. Complex structures are generated by…

Biomolecules · Quantitative Biology 2020-02-26 Joseph A. Morrone , Jeffrey K. Weber , Tien Huynh , Heng Luo , Wendy D. Cornell

Surgical action automation has progressed rapidly toward achieving surgeon-like dexterous control, driven primarily by advances in learning from demonstration and vision-language-action models. While these have demonstrated success in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Aiza Maksutova , Lalithkumar Seenivasan , Hao Ding , Jiru Xu , Chenhao Yu , Chenyan Jing , Yiqing Shen , Mathias Unberath

Model-based control usually relies on an accurate model, which is often obtained from CAD and actuator models. The more accurate the model the better the control performance. However, in bipedal robots that demonstrate high agility actions,…

Robotics · Computer Science 2021-07-27 Bolun Dai

Given native 2D contact map, protein 3D structure could be reconstructed with accuracy of 2A or better, and such reconstruction is a feasible computational approach for protein folding problem. The prediction accuracy from traditional…

Biomolecules · Quantitative Biology 2019-06-12 Yuhong Wang , Wei Li , Hongmao Sun , Kennie Cruz-Gutierrez

Federated learning with heterogeneous clients remains a significant challenge for deep learning, primarily due to client drift arising from inconsistent local updates. Existing federated optimization methods typically address this issue…

Machine Learning · Computer Science 2026-05-08 Junye Du , Zhenghao Li , Yushi Feng , Long Feng

Understanding protein structure-function relationships is a key challenge in computational biology, with applications across the biotechnology and pharmaceutical industries. While it is known that protein structure directly impacts protein…

Biomolecules · Quantitative Biology 2020-11-02 Nicolas Swenson , Aditi S. Krishnapriyan , Aydin Buluc , Dmitriy Morozov , Katherine Yelick

Segmenting multiple objects (e.g., organs) in medical images often requires an understanding of their topology, which simultaneously quantifies the shape of the objects and their positions relative to each other. This understanding is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Mehmet Bahadir Erden , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

The field of face recognition (FR) has undergone significant advancements with the rise of deep learning. Recently, the success of unsupervised learning and graph neural networks has demonstrated the effectiveness of data structure…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Jun Dan , Yang Liu , Jiankang Deng , Haoyu Xie , Siyuan Li , Baigui Sun , Shan Luo

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

Adaptive cognition requires structured internal models of objects and their relations. Predictive neural networks are often proposed to learn such world models, but how these are instantiated and how they support prediction remain unclear.…

Machine Learning · Computer Science 2026-05-11 Linda Ariel Ventura , Victoria Bosch , Tim C Kietzmann , Sushrut Thorat

Autoencoder recommenders have recently shown state-of-the-art performance in the recommendation task due to their ability to model non-linear item relationships effectively. However, existing autoencoder recommenders use fully-connected…

Information Retrieval · Computer Science 2020-08-19 Farhan Khawar , Leonard Kin Man Poon , Nevin Lianwen Zhang

Grounding a command to the visual environment is an essential ingredient for interactions between autonomous vehicles and humans. In this work, we study the problem of language grounding for autonomous vehicles, which aims to localize a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Hou Pong Chan , Mingxi Guo , Cheng-Zhong Xu

Most autonomous cars rely on the availability of high-definition (HD) maps. Current research aims to address this constraint by directly predicting HD map elements from onboard sensors and reasoning about the relationships between the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Khanh Son Pham , Christian Witte , Jens Behley , Johannes Betz , Cyrill Stachniss

State-of-the-art rigging methods typically assume a predefined canonical rest pose. However, this assumption does not hold for dynamic mesh sequences such as DyMesh or DT4D, where no canonical T-pose is available. When applied independently…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Ruipeng Wang , Langkun Zhong , Miaowei Wang

Autonomous surgery has attracted increasing attention for revolutionizing robotic patient care, yet remains a distant and challenging goal. In this paper, we propose an image-based framework for high-precision autonomous suturing operation.…

Robotics · Computer Science 2024-05-29 Hongbin Lin , Bin Li , Yunhui Liu , Kwok Wai Samuel Au

Purpose: Automated distinct bone segmentation from CT scans is widely used in planning and navigation workflows. U-Net variants are known to provide excellent results in supervised semantic segmentation. However, in distinct bone…

Image and Video Processing · Electrical Eng. & Systems 2023-02-01 Eva Schnider , Julia Wolleb , Antal Huck , Mireille Toranelli , Georg Rauter , Magdalena Müller-Gerbl , Philippe C. Cattin

Cross-robot policy learning -- training a single policy to perform well across multiple embodiments -- remains a central challenge in robot learning. Transformer-based policies, such as vision-language-action (VLA) models, are typically…

Robotics · Computer Science 2026-03-03 Kei Suzuki , Jing Liu , Ye Wang , Chiori Hori , Matthew Brand , Diego Romeres , Toshiaki Koike-Akino

Autoencoders are neural network formulations where the input and output of the network are identical and the goal is to identify the hidden representation in the provided datasets. Generally, autoencoders project the data nonlinearly onto a…

Signal Processing · Electrical Eng. & Systems 2019-07-10 Debjani Bhowick , Deepak K. Gupta , Saumen Maiti , Uma Shankar

Retargeting human kinematic reference motion onto a robot's morphology remains a formidable challenge. Existing methods often produce physical inconsistencies, such as foot sliding, self-collisions, or dynamically infeasible motions, which…

Robotics · Computer Science 2026-05-08 David Müller , Agon Serifi , Sammy Christen , Ruben Grandia , Espen Knoop , Moritz Bächer

Surgical automation can improve the accessibility and consistency of life saving procedures. Most surgeries require separating layers of tissue to access the surgical site, and suturing to reattach incisions. These tasks involve deformable…

Robotics · Computer Science 2024-05-17 Nikhil Uday Shinde , Xiao Liang , Fei Liu , Yutong Zhang , Florian Richter , Sylvia Herbert , Michael C. Yip