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The application of generative models in crystal structure prediction (CSP) has gained significant attention. Conditional generation--particularly the generation of crystal structures with specified stability or other physical properties has…

Materials Science · Physics 2026-01-14 Takanori Ishii , Kaoru Hisama , Kohei Shinohara

Periodic material or crystal property prediction using machine learning has grown popular in recent years as it provides a computationally efficient replacement for classical simulation methods. A crucial first step for any of these…

Machine Learning · Computer Science 2024-05-08 Jonathan Balasingham , Viktor Zamaraev , Vitaliy Kurlin

A novel method for crystal structure prediction, based on metadynamics and evolutionary algorithms, is presented here. This technique can be used to produce efficiently both the ground state and metastable states easily reachable from a…

Materials Science · Physics 2012-06-08 Qiang Zhu , Artem R. Oganov , Andriy O. Lyakhov

Fast and accurate crystal structure prediction (CSP) algorithms and web servers are highly desirable for exploring and discovering new materials out of the infinite design space. However, currently, the computationally expensive first…

Organic molecular crystals underpin technologies ranging from pharmaceuticals to organic electronics, yet predicting solid-state packing of molecules remains challenging because candidate generation is combinatorial and stability is only…

Crystal structure prediction (CSP) is now increasingly used in discovering novel materials with applications in diverse industries. However, despite decades of developments and significant progress in this area, there lacks a set of…

The discovery of new materials using crystal structure prediction (CSP) based on generative machine learning models has become a significant research topic in recent years. In this paper, we study invariance and continuity in the generative…

Machine Learning · Computer Science 2025-02-05 Yuji Tone , Masatoshi Hanai , Mitsuaki Kawamura , Kenjiro Taura , Toyotaro Suzumura

Crystal structures are characterized by atomic bases within a primitive unit cell that repeats along a regular lattice throughout 3D space. The periodic and infinite nature of crystals poses unique challenges for geometric graph…

Machine Learning · Computer Science 2024-03-19 Keqiang Yan , Cong Fu , Xiaofeng Qian , Xiaoning Qian , Shuiwang Ji

Crystalline structure prediction is an essential prerequisite for designing materials with targeted properties. Yet, it is still an open challenge in materials design and drug discovery. Despite recent advances in computational materials…

Machine Learning · Computer Science 2025-09-29 Emmanuel Jehanno , Romain Menegaux , Julien Mairal , Sergei Grudinin

Crystal structure prediction algorithms have become powerful tools for materials discovery in recent years, however, they are usually limited to relatively small systems. The main challenge is that the number of local minima grows…

Materials Science · Physics 2022-02-09 Hao Gao , Junjie Wang , Yu Han , Jian Sun

Solving black-box optimization problems with Ising machines is increasingly common in materials science. However, their application to crystal structure prediction (CSP) is still ineffective due to symmetry agnostic encoding of atomic…

Materials Science · Physics 2025-04-10 Chen Liang , Diptesh Das , Jiang Guo , Ryo Tamura , Zetian Mao , Koji Tsuda

We introduce CrystalFormer, a transformer-based autoregressive model specifically designed for space group-controlled generation of crystalline materials. By explicitly incorporating space group symmetry, CrystalFormer greatly reduces the…

Materials Science · Physics 2025-09-29 Zhendong Cao , Xiaoshan Luo , Jian Lv , Lei Wang

Determining the stability of chemical compounds is essential for advancing material discovery. In this study, we introduce a novel deep neural network model designed to predict a crystal's formation energy, which identifies its stability…

Materials Science · Physics 2026-04-21 V. Torlao , E. A. Fajardo

The combination of deep learning algorithm and materials science has made significant progress in predicting novel materials and understanding various behaviours of materials. Here, we introduced a new model called as the Crystal…

Materials Science · Physics 2024-05-21 Zijian Du , Luozhijie Jin , Le Shu , Yan Cen , Yuanfeng Xu , Yongfeng Mei , Hao Zhang

In computational chemistry, crystal structure prediction (CSP) is an optimization problem that involves discovering the lowest energy stable crystal structure for a given chemical formula. This problem is challenging as it requires…

Machine Learning · Computer Science 2023-10-17 Han Qi , Xinyang Geng , Stefano Rando , Iku Ohama , Aviral Kumar , Sergey Levine

Crystal structures are defined by the periodic arrangement of atoms in 3D space, inherently making them equivariant to SO(3) group. A fundamental requirement for crystal property prediction is that the model's output should remain invariant…

Computational Engineering, Finance, and Science · Computer Science 2025-10-24 Haowei Hua , Wanyu Lin

Crystals are the foundation of numerous scientific and industrial applications. While various learning-based approaches have been proposed for crystal generation, existing methods seldom consider the space group constraint which is crucial…

Machine Learning · Computer Science 2024-04-09 Rui Jiao , Wenbing Huang , Yu Liu , Deli Zhao , Yang Liu

Crystal structure prediction with theoretical methods is particularly challenging when unit cells with many atoms need to be considered. Here we employ a symmetry-driven structure search (SYDSS) method and combine it with density functional…

Materials Science · Physics 2018-12-05 Rustin Domingos , Kareemullah M. Shaik , Burkhard Militzer

We introduce a computational method to discover polymorphs in molecular crystals at finite temperature. The method is based on reproducing the crystallization process starting from the liquid and letting the system discover the relevant…

Chemical Physics · Physics 2020-04-10 Pablo M. Piaggi , Michele Parrinello

Synthetic polymers are versatile and widely used materials. Similar to small organic molecules, a large chemical space of such materials is hypothetically accessible. Computational property prediction and virtual screening can accelerate…

Machine Learning · Computer Science 2022-10-13 Matteo Aldeghi , Connor W. Coley