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Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

Artificial Intelligence · Computer Science 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Objective: Disease knowledge graphs are a way to connect, organize, and access disparate information about diseases with numerous benefits for artificial intelligence (AI). To create knowledge graphs, it is necessary to extract knowledge…

Machine Learning · Computer Science 2022-09-01 Yucong Lin , Keming Lu , Sheng Yu , Tianxi Cai , Marinka Zitnik

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity…

Signal Processing · Electrical Eng. & Systems 2024-10-14 Kaizhong Zheng , Shujian Yu , Baojuan Li , Robert Jenssen , Badong Chen

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

Machine Learning · Computer Science 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

Brain graph learning has demonstrated significant achievements in the fields of neuroscience and artificial intelligence. However, existing methods struggle to selectively learn disease-related knowledge, leading to heavy parameters and…

Machine Learning · Computer Science 2025-09-29 Ciyuan Peng , Nguyen Linh Dan Le , Shan Jin , Dexuan Ding , Shuo Yu , Feng Xia

Tremendous recent literature show that associations between different brain regions, i.e., brain connectivity, provide early symptoms of neurological disorders. Despite significant efforts made for graph neural network (GNN) techniques,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Xin Ma , Guorong Wu , Seong Jae Hwang , Won Hwa Kim

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Brain graphs (i.e, connectomes) constructed from medical scans such as magnetic resonance imaging (MRI) have become increasingly important tools to characterize the abnormal changes in the human brain. Due to the high acquisition cost and…

Machine Learning · Computer Science 2021-05-07 Alaa Bessadok , Mohamed Ali Mahjoub , Islem Rekik

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

Neurons and Cognition · Quantitative Biology 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Brain network analysis has emerged as pivotal method for gaining a deeper understanding of brain functions and disease mechanisms. Despite the existence of various network construction approaches, shortcomings persist in the learning of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Yongcheng Zong , Shuqiang Wang

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

Neurons and Cognition · Quantitative Biology 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Recent developed graph-based methods for diagnosing brain disorders using functional connectivity highly rely on predefined brain atlases, but overlook the rich information embedded within atlases and the confounding effects of site and…

Machine Learning · Computer Science 2025-10-16 Qianqian Liao , Wuque Cai , Hongze Sun , Dongze Liu , Duo Chen , Dezhong Yao , Daqing Guo
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