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Generative sequence modeling faces a fundamental tension between the expressivity of Transformers and the efficiency of linear sequence models. Existing efficient architectures are theoretically bounded by shallow, single-step linear…

Machine Learning · Computer Science 2026-02-13 Jie Jiang , Ke Cheng , Xin Xu , Mengyang Pang , Tianhao Lu , Jiaheng Li , Yue Liu , Yuan Wang , Jun Zhang , Huan Yu , Zhouchen Lin

Developing reliable and generalizable deep learning systems for medical imaging faces significant obstacles due to spurious correlations, data imbalances, and limited text annotations in datasets. Addressing these challenges requires…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Amar Kumar , Anita Kriz , Mohammad Havaei , Tal Arbel

Scaling LLM-based embodied agents from text-only environments to complex multimodal settings remains a major challenge. Recent work identifies a perception-reasoning-decision gap in standalone Vision-Language Models (VLMs), which often…

Artificial Intelligence · Computer Science 2026-05-08 Mohamed Salim Aissi , Clemence Grislain , Clement Romac , Laure Soulier , Mohamed Chetouani , Olivier Sigaud , Nicolas Thome

Simulation plays a central role in scientific discovery. In many applications, the bottleneck is no longer running a simulator; it is choosing among large families of plausible simulators, each corresponding to different forward…

Large language models (LLMs) solve complex problems by generating multi-step reasoning traces. Yet these traces are typically analyzed from only one of two perspectives: the sequence of tokens across different reasoning steps in the…

Computation and Language · Computer Science 2026-03-25 Ruidi Chang , Jiawei Zhou , Hanjie Chen

In this paper, we propose Precision-Informed Semantic Modeling (PRISM), a structured topic modeling framework combining the benefits of rich representations captured by LLMs with the low cost and interpretability of latent semantic…

Machine Learning · Computer Science 2026-04-06 Connor Douglas , Utkucan Balci , Joseph Aylett-Bullock

Pharmaceutical companies continue to seek innovative ways to explore whether a drug under development is likely to be suitable for all or only an identifiable stratum of patients in the target population. The sooner this can be done during…

Methodology · Statistics 2019-12-10 Thomas O. Jemielita , Devan V. Mehrotra

Deploying large language model (LLM)-driven conversational agents in enterprise settings requires prompts that are simultaneously correct at launch and resilient to the non-deterministic behavioral drift that characterizes production LLM…

Artificial Intelligence · Computer Science 2026-05-18 Keshava Chaitanya , Jahnavi Gundakaram

Background: Increasingly, decision-making in healthcare relies on computer models, be it clinical prediction models at point of care or decision-analytic models at the policymaking level. Given the important role models play in both…

Computation · Statistics 2022-02-22 Amin Adibi , Stephanie Harvard , Mohsen Sadatsafavi

Prototype-based interpretability methods provide intuitive explanations of model prediction by comparing samples to a reference set of memorized exemplars or typical representatives in terms of similarity. In the field of sequential data…

Machine Learning · Computer Science 2023-03-20 Yifei Zhang , Neng Gao , Cunqing Ma

Effective long-term memory in conversational AI requires synthesizing information across multiple sessions. However, current systems place excessive reasoning burden on response generation, making performance significantly dependent on…

Computation and Language · Computer Science 2025-09-16 Sangyeop Kim , Yohan Lee , Sanghwa Kim , Hyunjong Kim , Sungzoon Cho

Large Language Models (LLMs), constrained by their auto-regressive nature, suffer from slow decoding. Speculative decoding methods have emerged as a promising solution to accelerate LLM decoding, attracting attention from both systems and…

Artificial Intelligence · Computer Science 2026-02-03 Xuliang Wang , Yuetao Chen , Maochan Zhen , Fang Liu , Xinzhou Zheng , Xingwu Liu , Hong Xu , Ming Li

Forecasting is critical in areas such as finance, biology, and healthcare. Despite the progress in the field, making accurate forecasts remains challenging because real-world time series contain both global trends, local fine-grained…

Machine Learning · Computer Science 2026-01-01 Zihao Chen , Alexandre Andre , Wenrui Ma , Ian Knight , Sergey Shuvaev , Eva Dyer

In this paper, we present PRISM, a Promptable and Robust Interactive Segmentation Model, aiming for precise segmentation of 3D medical images. PRISM accepts various visual inputs, including points, boxes, and scribbles as sparse prompts, as…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Multivariate time series classification supports applications from wearable sensing to biomedical monitoring and demands models that can capture both short-term patterns and multi-scale temporal dependencies. Despite recent advances,…

Machine Learning · Computer Science 2026-04-07 Federico Zucchi , Thomas Lampert

We investigate the extent to which modern, neural language models are susceptible to structural priming, the phenomenon whereby the structure of a sentence makes the same structure more probable in a follow-up sentence. We explore how…

Computation and Language · Computer Science 2022-06-30 Arabella Sinclair , Jaap Jumelet , Willem Zuidema , Raquel Fernández

Automating experimental protocol design and execution remains as a fundamental bottleneck in realizing self-driving laboratories. We introduce PRISM (Protocol Refinement through Intelligent Simulation Modeling), a framework that automates…

Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval,…

Artificial Intelligence · Computer Science 2026-03-24 Xiao Han , Yuzheng Fan , Sendong Zhao , Haochun Wang , Bing Qin

We present PRISM-Consult, a clinician-aligned panel-of-experts architecture that extends the compact PRISM sequence model into a routed family of domain specialists. Episodes are tokenized as structured clinical events; a light-weight…

Artificial Intelligence · Computer Science 2026-01-21 Lionel Levine , John Santerre , Alexander S. Young , T. Barry Levine , Francis Campion , Majid Sarrafzadeh

Existing methods usually leverage a fixed strategy, such as natural language reasoning, code-augmented reasoning, tool-integrated reasoning, or ensemble-based reasoning, to guide Large Language Models (LLMs) to perform mathematical…

Artificial Intelligence · Computer Science 2025-09-30 Shihao Qi , Jie Ma , Ziang Yin , Lingling Zhang , Jian Zhang , Jun Liu , Feng Tian , Tongliang Liu
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