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Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Understanding neurocognitive computations will require not just localizing cognitive information distributed throughout the brain but also determining how that information got there. We review recent advances in linking empirical and…

Neurons and Cognition · Quantitative Biology 2019-10-22 Takuya Ito , Luke Hearne , Ravi Mill , Carrisa Cocuzza , Michael W. Cole

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

Neurons and Cognition · Quantitative Biology 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Brain organoids recapitulate a number of brain properties, including neuronal diversity. However, do they recapitulate brain structure? Using a hydrodynamic description for cell nuclei as particles interacting initially via an effective,…

Soft Condensed Matter · Physics 2021-12-15 Ahmad Borzou , J. M. Schwarz

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

Neurons and Cognition · Quantitative Biology 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

Fascinating and puzzling phenomena, such as landmark vector cells, splitter cells, and event-specific representations to name a few, are regularly discovered in the hippocampus. Without a unifying principle that can explain these divergent…

Neurons and Cognition · Quantitative Biology 2022-12-06 Rajkumar Vasudeva Raju , J. Swaroop Guntupalli , Guangyao Zhou , Miguel Lázaro-Gredilla , Dileep George

Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

Neural networks are prone to learning shortcuts -- they often model simple correlations, ignoring more complex ones that potentially generalize better. Prior works on image classification show that instead of learning a connection to object…

Machine Learning · Computer Science 2021-01-18 Axel Sauer , Andreas Geiger

Context. Generative models open up the possibility to interrogate scientific data in a more data-driven way. Aims: We propose a method that uses generative models to explore hypotheses in astrophysics and other areas. We use a neural…

Astrophysics of Galaxies · Physics 2018-12-06 Kevin Schawinski , M. Dennis Turp , Ce Zhang

Recent years have seen the emergence of many new neural network structures (architectures and layers). To solve a given task, a network requires a certain set of abilities reflected in its structure. The required abilities depend on each…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Adrien Courtois , Jean-Michel Morel , Pablo Arias

Artificial intelligence research to a great degree focuses on the brain and behaviors that the brain generates. But the brain, an extremely complex structure resulting from millions of years of evolution, can be viewed as a solution to…

Neurons and Cognition · Quantitative Biology 2017-03-07 Thomas E. Portegys

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

This review aims to contribute to the quest for artificial general intelligence by examining neuroscience and cognitive psychology methods for potential inspiration. Despite the impressive advancements achieved by deep learning models in…

Artificial Intelligence · Computer Science 2024-01-23 Florin Leon

Artificial Neural Networks (ANNs) are one of the most widely employed forms of bio-inspired computation. However the current trend is for ANNs to be structurally homogeneous. Furthermore, this structural homogeneity requires the application…

Neural and Evolutionary Computing · Computer Science 2024-03-26 Andrew Walter , Shimeng Wu , Andy M. Tyrrell , Liam McDaid , Malachy McElholm , Nidhin Thandassery Sumithran , Jim Harkin , Martin A. Trefzer

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

Neurons and Cognition · Quantitative Biology 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Many types of data from fields including natural language processing, computer vision, and bioinformatics, are well represented by discrete, compositional structures such as trees, sequences, or matchings. Latent structure models are a…

Machine Learning · Computer Science 2026-02-04 Vlad Niculae , Caio F. Corro , Nikita Nangia , Tsvetomila Mihaylova , André F. T. Martins

Data-driven generative modeling has made remarkable progress by leveraging the power of deep neural networks. A reoccurring challenge is how to enable a model to generate a rich variety of samples from the entire target distribution, rather…

Graphics · Computer Science 2019-09-04 Nadav Schor , Oren Katzir , Hao Zhang , Daniel Cohen-Or

Deep neural networks excel in mapping genomic DNA sequences to associated readouts (e.g., protein-DNA binding). Beyond prediction, the goal of these networks is to reveal to scientists the underlying motifs (and their syntax) which drive…

Genomics · Quantitative Biology 2024-10-10 Alex M. Tseng , Gokcen Eraslan , Tommaso Biancalani , Gabriele Scalia