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Demands for implementing original OSs that can achieve high I/O performance on PC/AT compatible hardware have recently been increasing, but conventional OS debugging environments have not been able to simultaneously assure their stability,…

Operating Systems · Computer Science 2011-11-09 Tadashi Takeuchi

We introduce 3DB: an extendable, unified framework for testing and debugging vision models using photorealistic simulation. We demonstrate, through a wide range of use cases, that 3DB allows users to discover vulnerabilities in computer…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Guillaume Leclerc , Hadi Salman , Andrew Ilyas , Sai Vemprala , Logan Engstrom , Vibhav Vineet , Kai Xiao , Pengchuan Zhang , Shibani Santurkar , Greg Yang , Ashish Kapoor , Aleksander Madry

Modern next-generation sequencing (NGS) projects routinely generate terabytes of data, which researchers commonly download from public repositories such as SRA or ENA. Existing download tools often employ static concurrency settings,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-08 Rasman Mubtasim Swargo , Engin Arslan , Md Arifuzzaman

Diffusion models produce high-quality synthetic data but suffer from slow inference. We propose 3D Variable-Step Denoising Diffusion Probabilistic Model (VS-DDPM) a framework engineered to maintain generative quality while accelerating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Nikoo Moradi , Gijs Luijten , Behrus Hinrichs-Puladi , Jens Kleesiek , Victor Alves , Jan Egger , André Ferreira

Advances in networks, accelerators, and cloud services encourage programmers to reconsider where to compute -- such as when fast networks make it cost-effective to compute on remote accelerators despite added latency. Workflow and…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-31 J. Gregory Pauloski , Valerie Hayot-Sasson , Logan Ward , Nathaniel Hudson , Charlie Sabino , Matt Baughman , Kyle Chard , Ian Foster

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

Distributed transaction processing often involves multiple rounds of cross-node communications, and therefore tends to be slow. To improve performance, existing approaches convert distributed transactions into single-node transactions by…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-19 Qiushi Zheng , Zhanhao Zhao , Wei Lu , Chang Yao , Yuxing Chen , Anqun Pan , Xiaoyong Du

Efficient and scalable deployment of machine learning (ML) models is a prerequisite for modern production environments, particularly within regulated domains such as healthcare and pharmaceuticals. In these settings, systems must balance…

Artificial Intelligence · Computer Science 2026-02-03 Ratul Ali

Low-cost, high-throughput DNA and RNA sequencing (HTS) data is the backbone of the life sciences. Genome sequencing is now becoming a part of Predictive, Preventive, Personalized, and Participatory (termed 'P4') medicine. All genomic data…

Major data centre providers are introducing RDMA-based networks for their tenants, as well as for operating the underlying infrastructure. In comparison to traditional socket-based network stacks, RDMA-based networks offer higher…

Operating Systems · Computer Science 2020-10-26 Maksym Planeta , Jan Bierbaum , Leo Sahaya Daphne Antony , Torsten Hoefler , Hermann Härtig

With the advent of hundreds of cores on a chip to accelerate applications, the operating system (OS) needs to exploit the existing parallelism provided by the underlying hardware resources to determine the right amount of processes to be…

Operating Systems · Computer Science 2025-01-07 Yao Xiao , Nikos Kanakaris , Anzhe Cheng , Chenzhong Yin , Nesreen K. Ahmed , Shahin Nazarian , Andrei Irimia , Paul Bogdan

The study of complex many-body systems via analysis of the trajectories of the units that dynamically move and interact within them is a non-trivial task. The workflow for extracting meaningful information from the raw trajectory data is…

Materials Science · Physics 2025-10-31 Simone Martino , Matteo Becchi , Andrew Tarzia , Daniele Rapetti , Giovanni M. Pavan

Stanford Medicine is building a new data platform for our academic research community to do better clinical data science. Hospitals have a large amount of patient data and researchers have demonstrated the ability to reuse that data and AI…

A large user base relies on software updates provided through package managers. This provides a unique lever for improving the security of the software update process. We propose a transparency system for software updates and implement it…

Cryptography and Security · Computer Science 2017-11-21 Benjamin Hof , Georg Carle

The persistence diagram, which describes the topological features of a dataset, is a key descriptor in Topological Data Analysis. The "Discrete Morse Sandwich" (DMS) method has been reported to be the most efficient algorithm for computing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-27 Eve Le Guillou , Pierre Fortin , Julien Tierny

To accommodate the needs of large-scale distributed P2P systems, scalable data management strategies are required, allowing applications to efficiently cope with continuously growing, highly dis tributed data. This paper addresses the…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-09-30 Bogdan Nicolae , Gabriel Antoniu , Luc Bougé

Efficient text indexing data structures have enabled large-scale genomic sequence analysis and are used to help solve problems ranging from assembly to read mapping. However, these data structures typically assume that the underlying…

Genomics · Quantitative Biology 2016-04-13 Nitish Gupta , Komal Sanjeev , Tim Wall , Carl Kingsford , Rob Patro

Verifiable ledger databases protect data history against malicious tampering. Existing systems, such as blockchains and certificate transparency, are based on transparency logs -- a simple abstraction allowing users to verify that a log…

Databases · Computer Science 2023-02-21 Cong Yue , Tien Tuan Anh Dinh , Zhongle Xie , Meihui Zhang , Gang Chen , Beng Chin Ooi , Xiaokui Xiao

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

Hand-sized Deoxyribonucleic acid (DNA) sequencing machines are of growing importance in several life sciences fields as their small footprints enable a broader range of use cases than their larger, stationary counterparts. However, as…

Hardware Architecture · Computer Science 2025-10-13 Abel Beyene , Zhongpan Wu , Yunus Dawji , Karim Hammad , Ebrahim Ghafar-Zadeh , Sebastian Magierowski