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Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

Image registration is a crucial task in signal processing, but it often encounters issues with stability and efficiency. Non-learning registration approaches rely on optimizing similarity metrics between fixed and moving images, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zihao Wang , Hervé Delingette

Deep learning algorithms that rely on extensive training data are revolutionizing image recovery from ill-posed measurements. Training data is scarce in many imaging applications, including ultra-high-resolution imaging. The deep image…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Maneesh John , Hemant Kumar Aggarwal , Qing Zou , Mathews Jacob

Non-rigid 3D registration, which deforms a source 3D shape in a non-rigid way to align with a target 3D shape, is a classical problem in computer vision. Such problems can be challenging because of imperfect data (noise, outliers and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Yuxin Yao , Bailin Deng , Weiwei Xu , Juyong Zhang

Deformable medical image registration is a fundamental task in medical image analysis. While deep learning-based methods have demonstrated superior accuracy and computational efficiency compared to traditional techniques, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Longitudinal image registration is challenging and has not yet benefited from major performance improvements thanks to deep-learning. Inspired by Deep Image Prior, this paper introduces a different use of deep architectures as regularizers…

In recent years, deep learning methods have been extensively developed for inverse imaging problems (IIPs), encompassing supervised, self-supervised, and generative approaches. Most of these methods require large amounts of labeled or…

Image and Video Processing · Electrical Eng. & Systems 2025-12-04 Ismail Alkhouri , Evan Bell , Avrajit Ghosh , Shijun Liang , Rongrong Wang , Saiprasad Ravishankar

Deformable image registration, i.e., the task of aligning multiple images into one coordinate system by non-linear transformation, serves as an essential preprocessing step for neuroimaging data. Recent research on deformable image…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Yao Su , Xin Dai , Lifang He , Xiangnan Kong

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

Image registration under domain shift remains a fundamental challenge in computer vision and medical imaging: when source and target images exhibit systematic intensity differences, the brightness constancy assumption underlying…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Jiahao Qin , Yiwen Wang

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Recent developments in neural networks have improved deformable image registration (DIR) by amortizing iterative optimization, enabling fast and accurate DIR results. However, learning-based methods often face challenges with limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Hang Zhang , Yuxi Zhang , Jiazheng Wang , Xiang Chen , Renjiu Hu , Xin Tian , Gaolei Li , Min Liu

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Deformable image registration is one of the fundamental tasks in medical imaging. Classical registration algorithms usually require a high computational cost for iterative optimizations. Although deep-learning-based methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Boah Kim , Inhwa Han , Jong Chul Ye

Image denoising is often empowered by accurate prior information. In recent years, data-driven neural network priors have shown promising performance for RGB natural image denoising. Compared to classic handcrafted priors (e.g., sparsity…

Image and Video Processing · Electrical Eng. & Systems 2022-02-16 Yu-Chun Miao , Xi-Le Zhao , Xiao Fu , Jian-Li Wang , Yu-Bang Zheng

Deformable image registration is inherently a multi-objective optimization (MOO) problem, requiring a delicate balance between image similarity and deformation regularity. These conflicting objectives often lead to poor optimization…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yi Zhang , Yidong Zhao , Qian Tao

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen