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Generalizability is seen as one of the major challenges in deep learning, in particular in the domain of medical imaging, where a change of hospital or in imaging routines can lead to a complete failure of a model. To tackle this, we…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Birk Torpmann-Hagen , Vajira Thambawita , Kyrre Glette , Pål Halvorsen , Michael A. Riegler

Source-free test-time adaptation for medical image segmentation aims to enhance the adaptability of segmentation models to diverse and previously unseen test sets of the target domain, which contributes to the generalizability and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yanyu Ye , Zhenxi Zhang , Wei Wei , Chunna Tian

Domain generalization studies the problem of training a model with samples from several domains (or distributions) and then testing the model with samples from a new, unseen domain. In this paper, we propose a novel approach for domain…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Zeyi Huang , Andy Zhou , Zijian Lin , Mu Cai , Haohan Wang , Yong Jae Lee

State-of-the-art stereo matching (SM) models trained on synthetic data often fail to generalize to real data domains due to domain differences, such as color, illumination, contrast, and texture. To address this challenge, we leverage data…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Shuangli Du , Jing Wang , Minghua Zhao , Zhenyu Xu , Jie Li

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

While achieving remarkable success for medical image segmentation, deep convolution neural networks (DCNNs) often fail to maintain their robustness when confronting test data with the novel distribution. To address such a drawback, the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Yuxin Kang , Hansheng Li , Xuan Zhao , Dongqing Hu , Feihong Liu , Lei Cui , Jun Feng , Lin Yang

In this paper, we consider the problem of domain generalization in semantic segmentation, which aims to learn a robust model using only labeled synthetic (source) data. The model is expected to perform well on unseen real (target) domains.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Zhun Zhong , Yuyang Zhao , Gim Hee Lee , Nicu Sebe

Clinical machine learning models experience significantly degraded performance in datasets not seen during training, e.g., new hospitals or populations. Recent developments in domain generalization offer a promising solution to this problem…

Machine Learning · Computer Science 2021-04-16 Haoran Zhang , Natalie Dullerud , Laleh Seyyed-Kalantari , Quaid Morris , Shalmali Joshi , Marzyeh Ghassemi

To segment medical images with distribution shifts, domain generalization (DG) has emerged as a promising setting to train models on source domains that can generalize to unseen target domains. Existing DG methods are mainly based on CNN or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Zihan Cheng , Jintao Guo , Jian Zhang , Lei Qi , Luping Zhou , Yinghuan Shi , Yang Gao

Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Ju Xu , Mengzhang Li , Zhanxing Zhu

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Single domain generalization (SDG) aims to train a robust model against unknown target domain shifts using data from a single source domain. Data augmentation has been proven an effective approach to SDG. However, the utility of standard…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Guangtao Zheng , Mengdi Huai , Aidong Zhang

Generalization capability to unseen domains is crucial for machine learning models when deploying to real-world conditions. We investigate the challenging problem of domain generalization, i.e., training a model on multi-domain source data…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Qi Dou , Daniel C. Castro , Konstantinos Kamnitsas , Ben Glocker

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

Over the years, the paradigm of medical image analysis has shifted from manual expertise to automated systems, often using deep learning (DL) systems. The performance of deep learning algorithms is highly dependent on data quality.…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Sidra Aleem , Teerath Kumar , Suzanne Little , Malika Bendechache , Rob Brennan , Kevin McGuinness

The objective of domain generalization (DG) is to enable models to be robust against domain shift. DG is crucial for deploying vision-language models (VLMs) in real-world applications, yet most existing methods rely on domain labels that…

Machine Learning · Computer Science 2026-02-02 Zhixing Li , Arsham Gholamzadeh Khoee , Yinan Yu

Domain Generalization (DG) is a fundamental challenge for machine learning models, which aims to improve model generalization on various domains. Previous methods focus on generating domain invariant features from various source domains.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Daoan Zhang , Mingkai Chen , Chenming Li , Lingyun Huang , Jianguo Zhang

Deep learning (DL) has shown remarkable success in various medical imaging data analysis applications. However, it remains challenging for DL models to achieve good generalization, especially when the training and testing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Yuemeng Li , Yong Fan

Domain generalization (DG), aiming at models able to work on multiple unseen domains, is a must-have characteristic of general artificial intelligence. DG based on single source domain training data is more challenging due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Qingyue Yang , Hongjing Niu , Pengfei Xia , Wei Zhang , Bin Li

Data augmentation is one of the most effective techniques for regularizing deep learning models and improving their recognition performance in a variety of tasks and domains. However, this holds for standard in-domain settings, in which the…

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