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Segmentation of tumors in brain MRI images is a challenging task, where most recent methods demand large volumes of data with pixel-level annotations, which are generally costly to obtain. In contrast, image-level annotations, where only…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Sergey Pavlov , Alexey Artemov , Maksim Sharaev , Alexander Bernstein , Evgeny Burnaev

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Clinical check-up reports are multimodal documents that combine page layouts, tables, numerical biomarkers, abnormality flags, imaging findings, and domain-specific terminology. Such heterogeneous evidence is difficult for laypersons to…

Computation and Language · Computer Science 2026-05-14 Sike Xiang , Shuang Chen , Kevin Qinghong Lin , Jialin Yu , Yijia Sun , Philip Torr , Amir Atapour-Abarghouei

Long-context audio reasoning is underserved in both training data and evaluation. Existing benchmarks target short-context tasks, and the open-ended generation tasks most relevant to long-context reasoning pose well-known challenges for…

Statistical inference on the cancer-site specificities of collective ultra-rare whole genome somatic mutations is an open problem. Traditional statistical methods cannot handle whole-genome mutation data due to their…

Methodology · Statistics 2023-01-02 Saptarshi Chakraborty , Zoe Guan , Colin B. Begg , Ronglai Shen

Skin cancer is one of the deadliest diseases and has a high mortality rate if left untreated. The diagnosis generally starts with visual screening and is followed by a biopsy or histopathological examination. Early detection can aid in…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Mahapara Khurshid , Mayank Vatsa , Richa Singh

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

This work is motivated by the scarcity of tools for accurate, unsupervised information extraction from unstructured clinical notes in computationally underrepresented languages, such as Czech. We introduce a stepping stone to a broad array…

Computation and Language · Computer Science 2023-11-17 Petr Zelina , Jana Halámková , Vít Nováček

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

Creating large-scale and well-annotated datasets to train AI algorithms is crucial for automated tumor detection and localization. However, with limited resources, it is challenging to determine the best type of annotations when annotating…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Yu-Cheng Chou , Bowen Li , Deng-Ping Fan , Alan Yuille , Zongwei Zhou

A growing body of work uses Natural Language Processing (NLP) methods to automatically generate medical notes from audio recordings of doctor-patient consultations. However, there are very few studies on how such systems could be used in…

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Accurate segmentation of Optical Coherence Tomography (OCT) images is crucial for diagnosing and monitoring retinal diseases. However, the labor-intensive nature of pixel-level annotation limits the scalability of supervised learning for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jiaqi Yang , Nitish Mehta , Xiaoling Hu , Chao Chen , Chia-Ling Tsai

Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Stefan M. Fischer , Johannes Kiechle , Daniel M. Lang , Jan C. Peeken , Julia A. Schnabel

The annotation of large scale histopathology image datasets remains a major bottleneck in developing robust deep learning models for clinically relevant tasks, such as mitotic figure classification. Folder-based annotation workflows are…

In clinical medicine, precise image segmentation can provide substantial support to clinicians. However, obtaining high-quality segmentation typically demands extensive pixel-level annotations, which are labor-intensive and expensive.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Tao Wang , Xinlin Zhang , Zhenxuan Zhang , Yuanbo Zhou , Yuanbin Chen , Longxuan Zhao , Chaohui Xu , Shun Chen , Guang Yang , Tong Tong

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Clinicians may rely on medical coding systems such as International Classification of Diseases (ICD) to identify patients with diseases from Electronic Health Records (EHRs). However, due to the lack of detail and specificity as well as a…

Computation and Language · Computer Science 2022-05-19 Jingqing Zhang , Atri Sharma , Luis Bolanos , Tong Li , Ashwani Tanwar , Vibhor Gupta , Yike Guo

The increasing availability of unstructured clinical narratives in electronic health records (EHRs) has created new opportunities for automated disease characterization, cohort identification, and clinical decision support. However,…

Computation and Language · Computer Science 2026-03-03 Fariba Afrin Irany , Sampson Akwafuo