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Accurate cell segmentation is critical for biological and medical imaging studies. Although recent deep learning models have advanced this task, most methods are limited to generic cell segmentation, lacking the ability to differentiate…

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

This paper addresses the semantic instance segmentation task in the open-set conditions, where input images can contain known and unknown object classes. The training process of existing semantic instance segmentation methods requires…

We transpose an optimal control technique to the image segmentation problem. The idea is to consider image segmentation as a parameter estimation problem. The parameter to estimate is the color of the pixels of the image. We use the…

Despite recent advances in data-independent and deep-learning algorithms, unstained live adherent cell instance segmentation remains a long-standing challenge in cell image processing. Adherent cells' inherent visual characteristics, such…

Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they…

An instance with a bad mask might make a composite image that uses it look fake. This encourages us to learn segmentation by generating realistic composite images. To achieve this, we propose a novel framework that exploits a new proposed…

In this work, we tackle the problem of instance segmentation, the task of simultaneously solving object detection and semantic segmentation. Towards this goal, we present a model, called MaskLab, which produces three outputs: box detection,…

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image colorization is the process of colorizing grayscale images or recoloring an already-color image. This image manipulation can be used for grayscale satellite, medical and historical images making them more expressive. With the help of…

We consider the problem of segmenting cell nuclei instances from Hematoxylin and Eosin (H&E) stains with weak supervision. While most recent works focus on improving the segmentation quality, this is usually insufficient for instance…

Images remain the largest data source in the field of healthcare. But at the same time, they are the most difficult to analyze. More than often, these images are analyzed by human experts such as pathologists and physicians. But due to…

We present a recurrent model for semantic instance segmentation that sequentially generates binary masks and their associated class probabilities for every object in an image. Our proposed system is trainable end-to-end from an input image…

Prevalent state-of-the-art instance segmentation methods fall into a query-based scheme, in which instance masks are derived by querying the image feature using a set of instance-aware embeddings. In this work, we devise a new training…

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Small sample instance segmentation is a very challenging task, and many existing methods follow the training strategy of meta-learning which pre-train models on support set and fine-tune on query set. The pre-training phase, which is highly…

We propose a new multiclass weighted loss function for instance segmentation of cluttered cells. We are primarily motivated by the need of developmental biologists to quantify and model the behavior of blood T-cells which might help us in…

Cell shape analysis is important in biomedical research. Deep learning methods may perform to segment individual cells if they use sufficient training data that the boundary of each cell is annotated. However, it is very time-consuming for…

Starting from a variational formulation, we present a model for image segmentation that employs both region statistics and edge information. This combination allows for improved flexibility, making the proposed model suitable to process a…

Weakly supervised instance segmentation has gained popularity because it reduces high annotation cost of pixel-level masks required for model training. Recent approaches for weakly supervised instance segmentation detect and segment objects…